Hyoxysonum

General characteristics. Structure:

Active ingredient: 1 g of Hydrocortisoni acetas, 3 g of Oxytetracyclinum of a hydrochloride.

Excipients: нипагин (methylparahydroxybenzoate), liquid paraffin, vaseline.

Pharmacological properties:

Pharmacodynamics. The combined drug, oppresses development of inflammatory reactions of skin, especially allergic origin complicated by a bacterial infection as a result of total action of the components which are a part of drug.

Oxytetracyclinum - an antibiotic from group of tetracyclines, has bacteriostatic action. It is active concerning gram-positive and gram-negative bacteria, Rickettsia spp., Treponema spp., Chlamydia spp., Mycoplasma spp.

The hydrocortisone - a glucocorticosteroid, renders antiinflammatory, antiallergic, anti-exudative and antipruritic effects. Slows down phagocytosis. Reduces formation of arachidonic acid from phospholipids of cellular covers due to oppression of activity of a phospholipase of A2. Release of the interleykin and other cytokines possessing antiinflammatory action oppresses; slows down release of a histamine and emergence of local allergic reactions. Reduces protein synthesis and adjournment of collagen in skin, interferes with development of connecting fabric, weakens proliferative processes.

Indications to use:

Dermatitis of newborns (violent and exfoliative), the infected intertrigo, folliculites, a furunculosis, an anthrax, impetigo, an erysipelatous inflammation; the infected eczemas and wounds, erosion; small tortoiseshell of the newborn; simple and allergic dermatitis, seborrhea; solar erythema; multiformny exudative erythema; stings of insects; allergic and purulent diseases of outside acoustical pass; varicose ulcers of a shin, burns, freezing injuries.

Route of administration and doses:

Outwardly. 1-3 times a day apply 0,5-1 g on affected areas or on a sterile gauze with which cover skin with a thin layer, having tied up bandage. Duration of treatment is individual and depends on extent of defeat and localization.

The course of treatment should not exceed 2 weeks. At use of drug on face skin it is necessary to apply ointment 1 time a day a thin layer or pointwise on elements, at the same time the course of treatment should not exceed 7-10 days.

Features of use:

During treatment it is not necessary to carry out by glucocorticosteroids vaccination against smallpox and to plan other types of immunization during treatment (in connection with immunodepressive effect of glucocorticosteroids).

In need of use of drug on face skin, treatment has to be short, in connection with the increased absorption and a possibility of emergence of side effect.

Side effects:

Irritation of skin, itch, rash; superinfection, allergic reactions. At use on face skin: telangiectasias, an atrophy of hypodermic cellulose in a mouth.

At prolonged use and/or drawing on big surfaces - system pobochnyeeffekta of glucocorticosteroids.

Contraindications:

Hypersensitivity, tuberculosis cutis, skin tumors, precancerous states, mycosis, viral diseases of skin (herpes, chicken pox); pregnancy, the lactation period (at use on the extensive centers of defeat).

Storage conditions:

List B. In the dry place, at a temperature from 12 to 15 °C. To store in the place, unavailable to children. Not to use drug after the date specified on packaging. A period of validity - 3 years.

Issue conditions:

According to the recipe

Packaging:

On 10 g in a tuba aluminum. Each tuba together with the application instruction is placed in a pack from a cardboard.