Акридерм® SK

General characteristics. Structure:

Active ingredients: 0,64 mg of betamethasone of Dipropionas and 30 mg of salicylic acid.

Excipients: vaseline, liquid paraffin.

The combined drug for external use rendering antiinflammatory, antiallergic, antiseptic, keratolytic action.

Pharmacological properties:

Pharmacodynamics. Betamethasone Dipropionas — the glucocorticosteroid, renders antiinflammatory, antiallergic, anti-exudative, antiedematous and antipruritic action. Slows down accumulation of leukocytes, release of lizosomalny enzymes and pro-inflammatory mediators in the inflammation center, phagocytosis oppresses, reduces vascular and fabric permeability, interferes with formation of inflammatory hypostasis.

Salicylic acid provides keratolytic, antimicrobic action, eliminates horn stratifications and promotes deeper penetration of a glucocorticosteroid.

Indications to use:

Topical treatment of the dermatosis which is followed by a hyperkeratosis: psoriasis, limited and diffusion neurodermatitis, red flat deprive, eczema, disgidrotichesky dermatitis, an ichthyosis and ikhtiozoformny changes.

Route of administration and doses:

Outwardly. Акридерм® SK apply with a thin layer on an affected area of skin 2 times a day — in the morning and in the evening. Other frequency of use can be established by the doctor, proceeding from disease severity.

In mild cases ointment is enough to be applied, as a rule, once a day; at more severe defeats more frequent use can be necessary.

Features of use:

If the signs of hypersensitivity or irritation of skin connected using drug are noted it is necessary to stop treatment and to pick up to the patient adequate therapy.

At long treatment, when putting drug on the extensive surfaces of skin, when using occlusive bandages, and also at children system absorption of glucocorticosteroids is possible.

To children since 1 drug is appointed only according to strict indications and under medical control as development of the system side effects connected with betamethasone is possible. At use of drug on extensive surfaces and/or under an occlusive bandage function suppression гипоталамо - pituitary and adrenal system and development of symptoms of a hypercorticoidism is possible, decrease in excretion of a growth hormone, increase in intracranial pressure can be observed.

On face skin more often than on other body surfaces, after prolonged treatment atrophic changes can be shown by glucocorticosteroids of local action; the course of treatment in this case should not exceed 5 days.

Акридерм® SK ointment is not intended for use in ophthalmology. To avoid hit of drug in eyes. At long use of drug its cancellation should be carried out gradually.

At pregnancy and in the period of a lactation. Safety of topical administration of glucocorticosteroids at pregnant women is not established; prescription of medicines of this group during pregnancy is justified only if the potential advantage exceeds possible risk. During pregnancy drugs of this group should not be used in high doses or a long time. It is not established whether topical administration of glucocorticosteroids the reason of emergence them in mother's milk therefore it is necessary to resolve an issue of the breastfeeding termination can become.

Side effects:

At topical administration of glucocorticosteroids can be observed: burning, irritation, xeroderma, folliculitis, hypertrichosis, aknepodobny rashes, hypopigmentation, perioral dermatitis, allergic contact dermatitis. At prolonged use, and also use of occlusive bandages — maceration of skin, consecutive infection, a skin atrophy, a heat rash, a purpura.

When drawing on extensive body surfaces, generally at children, emergence of system side effects of glucocorticosteroids and salicylates is possible.

At emergence of the side reactions which are not described in the instruction it is necessary to see a doctor.

Interaction with other medicines:

Interaction with other medicines is not revealed.

Contraindications:

Hypersensitivity to any of drug components, a tuberculosis cutis, perioral dermatitis, pink eels (rozatsea), trophic ulcers against the background of chronic venous insufficiency, a skin tumor (a carcinoma cutaneum, a nevus, an atheroma, an epithelioma, a melanoma, a hemangioma, a xanthoma, sarcoma); skin displays of syphilis, chicken pox, a herpes simplex, skin postvaccinal reactions, open wounds, the lactation period, children's age till 1 year.

Overdose:

The acute overdose is improbable, however, at excessive or prolonged use of drug the chronic overdose which is followed by hypercorticoidism signs is possible: hyperglycemia, glucosuria, reversible oppression of function of bark of adrenal glands, manifestation of a syndrome of Cushing.

Treatment. The corresponding symptomatic treatment is shown. In case of chronic toxic action gradual drug withdrawal is recommended.

Storage conditions:

At a temperature from 15 °C to 25 °C. To store in the place, unavailable to children. Not to apply after a period of validity. A period of validity - 3 years.

Issue conditions:

Without recipe

Packaging:

Ointment for external use. On 15 g and 30 g in a tuba aluminum. Each tuba together with the application instruction is placed in a pack from the card