Diclofenac, gel of 5% 40 G
Producer: JSC Krasnaya zvezda Ukraine
Code of automatic telephone exchange: M02A A15
Release form: Soft dosage forms. Gel.
General characteristics. Structure:
Indications to use:
Symptomatic treatment of pain, inflammation and hypostasis: at damage of soft tissues: injuries of sinews, sheaves, muscles and joints (for example, owing to dislocation, stretching, bruises); sports injuries; at the localized forms of rheumatism of soft tissues: tendinitis (including "a tennis elbow"), bursitis, humeral syndrome and periartropatiya; at the localized forms of degenerative rheumatism (an osteoarthritis of peripheral joints and the ridge).
Route of administration and doses:
Usually 2–4 g of Diclofenac (a strip of gel of 4-8 cm) apply on affected areas of a body 2–3 times a day with a thin layer and slightly rub.
Diclofenac can be applied in combination with an ionophoresis. This form of an electrotherapy allows to increase extent of penetration of drug through skin. Diclofenac has to be applied under a negative pole (cathode). Treatment duration – 10–14 days.
Assessment of side reactions is presented on the frequency of manifestations: very widespread (≥ 1/10), extended (≥ 1/100, ≤ 1/10), not widespread (≥ 1/1000, ≤ 1/100), seldom widespread (≥ 1/10 000), very seldom widespread (≤ 1/10 000).
From skin: not widespread – an itch, reddening, a dieback, burning, emergence of hypostases and vesicles, papules, pustules, a peeling and a xeroderma, dermatitis (including contact dermatitis); seldom widespread – violent dermatitis; very seldom widespread – reactions of a photosensitivity, generalized skin rashes, eczema.
From immune system: very seldom widespread – hypersensitivity reactions (a Quincke's disease of the person), an asthma.
From respiratory system: very seldom widespread – bronchial asthma.
From a digestive tract: side reactions arise very seldom after topical administration of the drugs containing diclofenac.
At use of gel in high doses or its drawings on big sites of skin it is impossible to exclude a possibility of emergence of system side reactions, and also reactions of hypersensitivity in the form of an angioedema, dispny.
Interaction with other medicines:
Diclofenac can strengthen effect of the drugs causing a fotosensobilization. Clinically significant interaction with other medicines is not described.
Hypersensitivity to diclofenac or to other non-steroidal anti-inflammatory drugs, to propylene glycol or to other components of drug. Existence in the anamnesis of attacks of bronchial asthma, small tortoiseshell or acute rhinitis, nasal polyps, angioedema, especially at patients with hypersensitivity to all types of analgetics and antirheumatic means. A peptic ulcer of a stomach and duodenum in an aggravation stage. Pregnancy period (last trimester). Children's age up to 12 years.
Tuba, 40 g