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Препарат Акридерм® . ОАО "Химико-фармацевтический комбинат "АКРИХИН" Россия

Producer: JSC Chemical and Pharmaceutical Plant AKRIKHIN Russia

Code of automatic telephone exchange: D07AC01

Release form: Soft dosage forms. Cream.

Indications to use: Seborrheal dermatitis. Atopic dermatitis. Neurodermatitis. Skin itch. Eczema. Solar dermatitis. Disgidrotichesky dermatitis (Помфоликс). Psoriasis. Contact dermatitis.

General characteristics. Structure:

Active ingredient: 0,64 mg of betamethasone of Dipropionas.

Excipients: methylparahydroxybenzoate (нипагин), paraffin, vaseline, propylene glycol, a liquid paraffin, the wax emulsifying dinatrium эдетат (Trilonum of B), sulfite sodium heptahydrate, the water purified.

Pharmacological properties:

Pharmacodynamics. The betamethasone corticosteroid Dipropionas renders antiinflammatory, antiallergic, anti-exudative, antiedematous and antipruritic action. Slows down accumulation of leukocytes, release of lizosomalny enzymes and antiinflammatory mediators in the inflammation center, phagocytosis oppresses, reduces vascular and fabric permeability, interferes with formation of inflammatory hypostasis.

Indications to use:

- allergic diseases of skin (including acute, subacute and chronic contact dermatitis, professional dermatitis, seborrheal dermatitis, atopic dermatitis, solar dermatitis, neurodermatitis, skin itch, disgidrotichesky dermatitis, eczema);
- acute and chronic forms of not allergic dermatitis;
- psoriasis.

Route of administration and doses:

Outwardly. Акридерм® apply with a thin layer on an affected area of skin 2 times a day - in the morning and in the evening. Other frequency of use can be established by the doctor, proceeding from disease severity. In mild cases cream is enough to be applied, as a rule, once a day; at more severe defeats more frequent use can be necessary.

Duration of treatment depends on efficiency and portability of therapy and makes 2-4 weeks.

If clinical improvement does not occur, it is necessary to specify the diagnosis.

Features of use:

If the signs of hypersensitivity or irritation of skin connected using drug are noted it is necessary to stop treatment and to pick up to the patient adequate therapy. At long treatment, when putting drug on the extensive surfaces of skin, when using occlusive bandages, and also at children system absorption of glucocorticosteroids is possible.

To children since 1 drug is appointed only according to strict indications and under medical control as development of the system side effects connected with betamethasone is possible. At use of drug on extensive surfaces and/or under an occlusive bandage function suppression гипоталамо - pituitary and adrenal system and development of symptoms of a hypercorticoidism is possible, decrease in excretion of a growth hormone, increase in intracranial pressure can be observed.

On face skin more often than on other body surfaces, after prolonged treatment atrophic changes can be shown by glucocorticosteroids of local action; the course of treatment in this case should not exceed 5 days.

Акридерм® cream is not intended for use in ophthalmology. To avoid hit of drug in eyes.

At long use of drug its cancellation should be carried out gradually.

Use at pregnancy and in the period of a lactation. Safety of topical administration of glucocorticosteroids at pregnant women is not established; prescription of medicines of this group during pregnancy is justified only if the potential advantage exceeds possible risk. During pregnancy drugs of this group should not be used in high doses or a long time. It is not established whether topical administration of glucocorticosteroids the reason of emergence them in mother's milk therefore it is necessary to resolve an issue of the breastfeeding termination can become.

Side effects:

At topical administration of glucocorticosteroids can be observed: burning, irritation, xeroderma, folliculitis, hypertrichosis, aknepodobny rashes, skin itch, striya, heat rash, hypopigmentation, perioral dermatitis. At prolonged use, and also use of occlusive bandages — maceration of skin, consecutive infection, a skin atrophy, a heat rash, a purpura, a local hirsutism, a teleangiectasia.

When drawing on extensive body surfaces, generally at children emergence of system side effects of glucocorticosteroids (gastritis, an ulceration of a mucous membrane of a GIT, a hyperglycemia, a glucosuria, reversible oppression of function of bark of adrenal glands, manifestation of a syndrome of Cushing) is possible.

At emergence of the side reactions which are not described in the instruction it is necessary to see a doctor.

Interaction with other medicines:

Interaction of drug with other medicines is not revealed.


Hypersensitivity to any of drug components, bacterial, fungus skin diseases, a tuberculosis cutis, skin displays of syphilis, chicken pox, a herpes simplex, skin postvaccinal reactions, open wounds, trophic ulcers of a shin, a rozatse, vulgar eels, a carcinoma cutaneum, nevus, atheroma, a melanoma, a hemangioma, xanthoma, sarcoma, the period of a lactation and children's age till 1 year.


The acute overdose is improbable, however, at excessive or prolonged use of drug the chronic overdose which is followed by hypercorticoidism signs is possible: hyperglycemia, glucosuria, reversible oppression of function of bark of adrenal glands, manifestation of a syndrome of Cushing.

Treatment. The corresponding symptomatic treatment is shown. In case of chronic toxic action gradual drug withdrawal is recommended.

Storage conditions:

Drug cannot be used after the expiry date specified on packaging. At a temperature from 15 to 25 °C in the place, unavailable to children. A period of validity - 4 years.

Issue conditions:

Without recipe


Cream for external use of 0,064%. On 15 g or 30 g in a tuba aluminum. Each tuba together with the instruction on a medical use is placed in a pack from a cardboard.

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