Chronic prostatitis

Description:

Chronic prostatitis is to a prostate with a long current, it can be the bacterial and not bacterial nature (a syndrome of chronic pelvic pain).

Symptoms of Chronic prostatitis:

The symptomatology of chronic not bacterial prostatitis can come to light in two options:
    * An inflammatory chronic pelvic pain syndrome (in a prostate secret, urine and an ejaculate leukocytes are defined).
    * A noninflammatory chronic pelvic pain syndrome at which signs of an inflammation are absent.
Chronic prostatitis (syndrome of chronic pelvic pain) is one of the most widespread diseases and makes 90-95% of all forms of prostatitis. This disease can develop at any age, but most often affects men at the age of about 30 years. Criteria of diagnosis of this disease are:
    * Long (not less than 3 months) existence of pains in a small pelvis, a crotch and generative organs.
    * Lack of signs of an inflammation in a prostate secret, urine and an ejaculate.
    * Negative takes 2nd stakanny test of Nickel
Symptomless chronic prostatitis. Current of this form of prostatitis, as a rule, asymptomatically. A persistent bacteriuria and a leukocyturia which are the main signs in diagnosis of this pathology can be the only symptoms of a disease.

Reasons of Chronic prostatitis:

Infectious theory.
According to this theory bacterial damage of tissues of prostate gland is an origin of a syndrome of chronic pelvic pain. As agents capable to strike tissues of a prostate such microorganisms as are considered: Trichomonas vaginalis, Chlamydia trachomatis, Ureaplasma urealiticum, koagulazo-negative staphylococcus, causative agent of gonorrhea (Neisseria gonorrhoeae), tubercular stick (Mycobacterium tuberculosis) and viruses (Herpes simplex, Cytomegalovirus). This theory is spoken well by detection by means of special methods of traces of a bacterial invasion in samples of tissues of prostate and a secret.
Theory of a chemical inflammation.
According to this theory the inflammation of tissues of prostate gland occurs under the influence of an intraprostatichesky uric reflux (urine penetration deep into of prostate tissue).
The following conditions are necessary for emergence of an inflammation of tissues of prostate under the influence of components of urine: high pressure of urine at an urination (arises in case of existence of obstacles in the lower urinary tract, for example, after an ejaculation and stagnation of the remains of sperm in urinary tract), existence of certain changes from prostatic channels, total absence of bacteria in urine, absence in an urethra of pathogenic bacteriums. Authors of this theory — B. E. Person and G. Ronquist (1996), consider that process of an aseptic inflammation is started by chemical — the urate getting to canals of a prostate together with urine.
Immune theory.
The theory of the immune nature of chronic not bacterial prostatitis is based on the assumption that tissues of a prostate gland are surprised in response to adjournment in tissues of a prostate of various antigens or owing to autoimmune process. Genetic predisposition and a persistention in a prostate of bacterial antigens can be the factors contributing to development of autoimmune process. An opportunity experimental reproduction of autoimmune prostatitis supports this theory.
Neurogenic theory.
Main issue of this theory is the neurogenic inflammation which arises in bodies of the urinogenital highway under the influence of biologically active agents emitted by nerve terminations (substance P). Release of biologically active agents nerve terminations is a consequence of peripheral pelvic neuropathy. Similar neurogenic inflammatory process in the field of urinogenital bodies can be experimentally reproduced on animals who are exposed to various stressful influences.

Treatment of Chronic prostatitis:

In treatment of chronic prostatitis apply various methods:
  1. Antibacterial therapy — provides use of antibiotics (for example Norfloksatsin, Ofloksatsin, Doksitsiklin, Eritromitsin) and is directed to suppression of the infectious factor playing a significant role in a disease pathogeny.
  2. Alpha adrenoblockers (Terazozin, Doksazozin, Tamsulozin) — influence specific adrenergic receptors of a prostate and facilitate disease symptoms.
  3. Antiinflammatory drugs (preferential TsOG-2 blockers: An ibuprofen, Diclofenac, Indometacin, Tselekoksib) — influencing local inflammatory process.
  4. Phytodrugs. As means  for treatment of problems with a prostate use drugs of a plant origin. At treatment of prostatitis Likoprofit who contains lycopene - a carotinoid, vitamins, microelements and extracts of useful plants is often applied. Drug selectively collects in prostate tissues, reduces the inflammation phenomena, promotes strengthening of protective functions, protects cells from defeat by free radicals and controls process of excessive growth of tissues of prostate gland. At administration of drug improvement of quality of an ejaculate and increase in quantity of active forms of spermatozoa is noted, and also the antimicrobic effect increases. At the expense of the complex and balanced composition of drug at prostatitis there is an elimination of the difficulties connected with an urination,  weakening of a pain syndrome
  5. Hormonal therapy

Drug treatment of chronic prostatitis / syndrome of chronic pelvic pain is carried out for 2-4 weeks. In parallel with drug treatment use also such methods as:
    * Massage of a prostate
    * Physical therapy
    * Exercises on a relaxation
    * Acupuncture
    * Surgical methods of treatment

Forecast. Treatment of chronic prostatitis is a complex problem. Often, despite the made therapeutic efforts quite modest results are observed. So, 50%-ti decrease in intensity of symptoms are considered good result of the undertaken treatment.
Therapy of chronic aseptic prostatitis includes purpose of antimicrobic and antiinflammatory drugs. It should be noted that in certain cases the prostate cancer has a clinical picture similar to chronic asymptomatic prostatitis. For differential diagnosis these two disease appoint definition of the DOG (PSA) (prostates a specific antigen) which concentration considerably increases in case of prostate tumors.