medicalmeds.eu Medicines The means influencing the alimentary system and metabolic processes. Ascorbic acid таб. 0,025 No. 10, 50,100

Ascorbic acid таб. 0,025 No. 10, 50,100

Producer: CJSC Lekhim-Kharkiv Ukraine

Code of automatic telephone exchange: A11GA01

Release form: Firm dosage forms. Tablets.

Indications to use: Deficit of vitamin C. Uterine bleeding. Nasal bleeding. Addison's disease. Fracture of bones. Dystrophy.

General characteristics. Structure:

Active ingredient: ascorbic acid; structure: 1 tablet contains ascorbic acid – 0,025 g; excipients: granulated sugar, potato starch or starch corn, povidone 25, fragrance orange powdery, magnesium stearate.

Pharmacological properties:

Water-soluble vitamin, eliminates deficit of ascorbic acid in an organism. Activates activity of hemadens, regulates all types of exchange, fibrillation, an angenesis, formation of steroid hormones, synthesis of collagen, procollagen, maintains normal permeability of capillaries. Regulates cholesterol contents in blood, promotes accumulation in a glycogen liver. Due to activation of respiratory enzymes in a liver amplifies its detoksikatsionny and belkovoobrazuyushchy functions, synthesis of a prothrombin increases.

Promotes absorption of iron in intestines and takes part in hemoglobin synthesis. Ascorbic acid, showing the stimulating influence on an organism in general, raises its adaptation opportunities, resistance to infections.

Indications to use:

Diseases at which additional administration of vitamin C is required: for prevention and treatment of deficit of vitamin C in an organism, at bleedings (the uterine, pulmonary, nasal, hemorrhagic diathesis, bleedings arising at a radial illness), at various intoxications and infectious diseases, a nephropathy of pregnant women, Addison's disease, overdose of anticoagulants, fractures of bones it is also long not healing wounds, dystrophy, observance of reducing diets, in the period of reconvalescence, pregnancy and feeding by a breast, at the raised intellectual and exercise stresses, and also for nonspecific prevention of infectious diseases.

Cautions at use. Before an initiation of treatment consult to the doctor!

With caution patients should take drug with hypercoagulation.

At an urolithiasis the daily dose of ascorbic acid should not exceed 1 g. When using ascorbic acid in high doses control of function of kidneys and level of arterial pressure, and also function of a pancreas is necessary. The lack of vitamin C of a diet of pregnant women can be dangerous to a fruit, however its use in high doses during pregnancy can also negatively affect fetation. Ascorbic acid gets into breast milk therefore during feeding by a breast vitamin C should be accepted under control of the doctor.

Ascorbic acid as a reducer can change results of different laboratory tests (content in blood of glucose, bilirubin, activity of transaminases, lactate dehydrogenases).

Route of administration and doses:

Ascorbic acid is appointed inside after food. Tablets are chewed and washed down with a small amount of water.

Medical doses for adults – on 0,05 - 0,1 g of 3 - 5 times a day within 2 weeks. To children from 3 to 18 years, depending on age and the nature of a disease, appoint on 0,05 - 0,1 g a day 2 - 3 receptions. A course of treatment – 2 weeks.

With the preventive purpose ascorbic acid is appointed the adult in a daily dose of 0,1 g, to children from 3rd to 11 years – on 0,025 g 2 times a day, from 11 to 14 years – on 0,025 g 3 times a day.

During pregnancy and feeding by a breast the daily dose makes 0,3 g (300 mg) at reception within 10 - 15 days, further – on 0,1 g (100 mg). Duration of treatment is defined by the nature of pathological process and efficiency of therapy (mono-or complex).

Side effects:

At prolonged use in high doses negative influence on a digestive tract (nausea, vomiting, heartburn, ponosa) and an urinary system - formation of urinary, tsistinovy and oxalic stones, a headache is not excluded. With a lack of glyukozo-6-fosfatdegidrogenazy blood cells can cause hemolysis of erythrocytes in patients. Irritation of a mucous membrane of a stomach, hypertensia, hyperglycemia, thrombocytosis, leukocytosis. Hyperexcitability, sleep disorder, emergence of mikroangiopatiya, erythrocytopenia, allergic reactions.

In case of any unusual reactions consult to the doctor of rather further use of drug.

Interaction with other medicines:

If you accept any other medicines, surely consult with the doctor about a possibility of use of drug!

Absorption of Ascorbic acid decreases at simultaneous use of peroral contraceptive means, the use of fresh fruit or vegetable juice, alkaline drinks. Ascorbic acid at oral administration increases absorption of penicillin, iron, reduces efficiency of heparin and indirect anticoagulants, increases risk of development of a crystalluria at treatment by salicylates.

Reduces anticoagulating effect of derivatives of coumarin. Improves absorption in intestines of iron preparations. Increases the general clearance of alcohol. Drugs of a quinolinic row, Calcii chloridum, salicylates, corticosteroids at prolonged use reduce reserves of ascorbic acid.

The concomitant use of Ascorbic acid and Deferoxaminum increases fabric toxicity of iron, especially in a cardiac muscle that can lead to a blood circulatory system decompensation. It can be accepted only in 2 h after Deferoxaminum injection. Long reception of high doses of vitamin C at persons who are treated by Disulfiramum slows down reaction Disulfiramum alcohol. High doses of drug reduce efficiency of tricyclic antidepressants.

Contraindications:

Hypersensitivity (allergy) to ascorbic acid and other components of drug; thromboses, thrombophlebitises. Children up to 3 years.

Overdose:

Symptoms: nausea, vomiting, dizziness, headache. In case of side effect it is necessary to stop administration of drug and to see a doctor. Therapy is symptomatic.