Bisacodyl

General characteristics. Structure:

Active ingredient: 5 mg of bisacodyl in 1 tablet.

Excipients: lactose (sugar milk), sucrose (sugar), hypro rod (hydroxypropyl cellulose), calcium stearate, starch prezhelatinizirovanny, potato starch, methacrylic acid and ethyl acrylate copolymer [1:1] (Kollikut MAY of P100), povidone (Kollidon 30), polysorbate (twin 80), silicone emulsion, macrogoal 6000 (polyethyleneglycol 6000), ferrous oxide yellow, talc, titanium dioxide.

The medicine possessing aperient action. It is applied also by preparation of a large intestine for x-ray and endoscopic inspection.

Pharmacological properties:

Pharmacodynamics. Purgative. Causes irritation of the receptor device of a gut, exerts direct impact on a mucous membrane of intestines, strengthening its peristaltics and increasing secretion of slime in a large intestine.

Action comes in 6 h at intake (at reception before going to bed - in 8-12 h) and within the first hour at rectal administration.

Pharmacokinetics. It is not soaked up in intestines. Is pro-medicine, in the alkaline environment there is a hydrolysis to formation of the metabolite rendering irritant action on a mucous membrane of digestive tract.

Indications to use:

Hypotonic and atonic locks (including locks at elderly; locks after operations and childbirth). Regulation calla (hemorrhoids, proctitis, anal fissures). Preparation for surgeries, tool and X-ray inspections.

Route of administration and doses:

Inside, before going to bed or in 30 min. prior to a breakfast, to adults and children 14 years - 5-15 mg are more senior; 8-14 years - 5-10 mg; children are 3-7 years old - 5 mg.

Tablets are swallowed, without chewing and washing down with a small amount of water.

Features of use:

Not to apply for a long time.

Side effects:

Intestinal colic, diarrhea (dehydration, disturbance of water and electrolytic exchange, muscular weakness, spasms, lowering of arterial pressure), abdominal pain, meteorism, allergic reactions.

Interaction with other medicines:

Combined use with antacids can lead to premature dissolution of its cover and irritation of a stomach and duodenum.

It is not recommended to accept along with milk and alkaline mineral water.

Contraindications:

Hypersensitivity, intestinal impassability, the restrained hernia, acute inflammatory diseases of abdominal organs, peritonitis, bleedings from digestive tract, a metrorrhagia, cystitis, spastic locks, an acute proctitis, acute hemorrhoids, children's age up to 3 years, a hereditary lactose intolerance, deficit of lactase, a glucose/galactose sprue.

With care: pregnancy, lactation period, liver and/or renal failure.

Overdose:

Symptoms: diarrhea, dehydration, disturbance of water and electrolytic balance, hypopotassemia, atony of a large intestine.

Treatment: symptomatic.

Storage conditions:

In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 2 years. Not to use after the period of validity specified on packaging.

Issue conditions:

Without recipe

Packaging:

The tablets covered with a kishechnorastvorimy cover on 5 mg. On 10 or 20 tablets in a blister strip packaging. On 1, 2, 3 or 4 blister strip packagings with the application instruction in a pack from a cardboard.