Noksprey

General characteristics. Structure:

Active ingredient: oxymetazoline; 1 ml of solution contains 0,5 mg of oxymetazoline of a hydrochloride; excipients: left menthol, camphor racemic, eucalyptole, sodium hydrophosphate and/or sodium dihydrophosphate, dinatrium эдетат (Trilonum of B), a benzalkoniya chloride, propylene glycol, the water purified.

Pharmacological properties:

Noksprey — α-адреномиметик, derivative imidazoline treats vasoconstrictors for topical administration. At hit in a nasal cavity drug narrows arterioles of a mucous membrane of a nasal cavity owing to what hypostasis decreases, the hyperemia, exudation, is recovered nasal breath, allocations from a nose decrease. Noksprey reduces also puffiness of a mucous membrane around an opening of an Eustachian tube, improving a drainage at an eustachitis and average otitis. The essential oils which are a part of drug promote elimination of irritation of a mucous membrane of a nose, protect it from excessive drying. Local vasoconstriction of a mucous membrane of a nose and adnexal bosoms arises in 5-10 minutes after Noksprey's injection in a nasal cavity and lasts for 10-12 hours.

Indications to use:

Acute rhinitis of an allergic or infectious and inflammatory etiology, sinusitis, congestion of a nose and the complicated nasal breath at catarrhal diseases, an eustachitis, average otitis. For simplification of carrying out a rinoskopiya and other manipulations in a nasal cavity.

Route of administration and doses:

To children aged from 6 up to 12 years apply on 1 injection in each nasal course 2 times a day, to children 12 years and the adult — on 1-2 injections in each nasal course 2 times a day are more senior. Duration of use should not exceed 7 days.

Features of use:

It is necessary to avoid prolonged use and overdose of drug. Prolonged use of antiedematouses can lead to decrease in their efficiency. Abuse of these means can cause a mucosal atrophy of a nasal cavity and a reactive hyperemia with medicamentous rhinitis.

Use during pregnancy or feeding by a breast. During pregnancy and feeding by a breast use of drug is possible in case the expected advantage for mother exceeds potential risk for a fruit.

Ability to influence speed of response at control of motor transport or work with other mechanisms. In the recommended doses drug does not influence the speed of psychomotor reactions.

Children. Noksprey apply to children of 6 years.

Appropriate precautionary measures. The tip of a nozzle of a bottle is entered into each nasal course and sharply pressed once a bottle. During injection air is involved by a nose. It is not necessary to reject the head back and to overturn a bottle at Noksprey's injection. For the prevention of spread of an infection several persons should not use one bottle. Duration of use of drug should not exceed 7 days.

Side effects:

Sometimes — a burning sensation or dryness of nasal covers, sneezing. In rare instances — a reactive hyperemia. The repeated overdose at topical nasal administration results in such system sympathomimetic effects as tachycardia, sleeplessness, concern, increase in arterial pressure, a headache, nausea. Extremely seldom at Noksprey's use development of heavy reactions of hypersensitivity, including a Quincke's edema is possible. In case of side effects use of drug it is necessary to stop and see a doctor.

Interaction with other medicines:

Noksprey it is not necessary to apply at the same time with other local vasoconstrictors and means to intranasal introduction, and also with tricyclic antidepressants and inhibitors of a monoaminooxidase.

Contraindications:

Hypersensitivity to drug components; atrophic rhinitis; the increased intraocular pressure, especially at closed-angle glaucoma; pheochromocytoma; severe forms of cardiovascular diseases (arterial hypertension, stenocardia); metabolic disturbances (hyperthyroidism, diabetes mellitus); children's age up to 6 years. Contraindicated simultaneous use of inhibitors of a monoaminooxidase and other drugs which promote increase in arterial pressure.

Overdose:

At considerable overdose or at accidental use such symptoms inside can be noted: miosis, nausea, vomiting, cyanosis, hyperthermia, tachycardia, arrhythmia, vascular insufficiency, arterial hypertension, respiratory frustration, fluid lungs, cardiac standstill, mental disorders. Extremely seldom — oppression of the TsNS functions with possible development of a coma. At overdose of drug wash out a stomach and carry out symptomatic therapy.

Storage conditions:

To store at  a temperature from 2 °C to 30 °C. To store in the place, unavailable to children.

Period of validity. 3 years. It is not necessary to use drug after the termination of the period of validity specified on packaging.

Issue conditions:

Without recipe

Packaging:

On 15 or 20 ml in polymeric containers with traffic jams sprayers and covers with control of the first opening in a cardboard pack.