Bifidumbacterium

General characteristics. Structure:

Active ingredient: not less than 500 million colony-forming units (^5х108, WHICH) bifidobacteria.

Excipients: lactoses monohydrate.

Pharmacological properties:

Pharmacodynamics. Medicinal properties of drug define the lyophilized bifidobacteria (Bifidobacterium bifidum) inherent in the person which are contained in it live about the births having antagonistic activity against a wide range of pathogenic and conditionally pathogenic microorganisms.

High quantitative level of bifidobacteria in drug allows to normalize intestinal microflora and by that to improve activity of digestive tract, exchange processes, pristenochny digestion, to increase nonspecific resistance of an organism.

Indications to use:

Intestinal dysbioses of various etiology.

As a part of complex therapy: intestinal dysfunctions of an unspecified etiology; acute intestinal infections (dysentery, salmonellosis, эшерихиоз, иерсиниоз, rotavirusny infection, unspecified etiology); convalescents after acute intestinal infections; chronic diseases of the digestive system with intestinal microflora disturbance; children (including newborn and premature) at pneumonia, sepsis and others it is purulent - infectious diseases, and also at anemia, a hypotrophy, rickets for decrease in complications and increase in efficiency of the main treatment; allergic diseases; disbioz and inflammatory processes of female genitalias (bacterial vaginoses, including at pregnant women, bacterial colpitises, and also senile colpitises of the hormonal nature).

For prevention of dysbacterioses at reception of antibacterial drugs (including antibiotics), the glucocorticosteroids, drugs having ulcerogenic effect on digestive tract (including NPVP); at beam and chemotherapy; at a stressful situation and stay in extreme conditions; at often ill children of all age; to children with the burdened premorbidal state, been born prematurely or with prematurity signs, receiving antibiotics in the early neonatal period; to children whose mothers had heavy toxicoses, extragenital diseases had the long anhydrous period, had лактостаз, nipple cracks also resumed feeding by a breast after recovery from mastitis; to children of chest age at their early transfer into artificial feeding and feeding by donor milk.

For the purpose of prevention of mastitis for local processing of mammary glands of nursing mothers of group of "risk" (at women with the pulled-in flat nipple, decrease in its erection, existence of cracks).

Route of administration and doses:

• to children up to 6 months on 1 package 2-3 times a day, about 2-3 days if necessary frequency rate of administration of drug it is possible to increase to 4-6 times a day,
• to children 6 months and up to 3 years on 1 package 3-4 times a day are more senior,
• to children from 3 to 7 years on 1 package of 3-5 times a day,
• to children 7 years on 2 packages 3-4 times a day are more senior,
• the adult on 2 packages 3-4 times a day.

If necessary it is possible to increase frequency rate of administration of drug to 6 times a day. Course of treatment 3-4 weeks. If necessary it is possible to repeat a course of treatment 2-3 times, each course – in a month.

During the acute period at a severe disease with the expressed dysbacteriosis the daily dose of drug can be increased only to destination the attending physician. At use of drug in complex treatment of acute intestinal infections the course of treatment makes 7-10 days.

With the preventive purposes:

• to children up to 6 months on 1 package once a day,
• to children 6 months on 1 package 1-2 times a day are more senior,
• to children since 3 years on 2 packages 1-2 times a day,
• the adult on 2 packages 1-2 times a day.

A preventive course is conducted within 2-3 weeks 2-3 times a year.

Bifidumbacterium is accepted during meal, if necessary irrespective of meal. Drug before the use is mixed with liquid food, it is desirable fermented milk product, the newborn and to children of chest age – with maternal milk or mix for artificial feeding. It is possible to mix drug from 30-50 ml of boiled water of room temperature, at the same time poorly opalescent suspension of whitish or grayish color is formed. The received water suspension should be drunk, without trying to obtain full dissolution.

For topical administration:

- for processing of a mammary gland of the woman in childbirth 1 package of drug is poured out in 10-15 ml of boiled water of room temperature, impregnate with the received suspension a sterile tampon and process them area of a nipple and an areola in 20-30 minutes prior to each feeding of the child a breast, the tampon is left on the surface of a mammary gland prior to feeding, such processing to spend not less than 5 days,

- in gynecologic practice – contents of 2 packages of drug need to be poured out in 15-20 ml of boiled water of room temperature, to plentifully impregnate with the received suspension a tampon and to enter it into a vagina for 2-3 hours in the morning and in the evening, a course of treatment of 8-10 days,

- at chronic diseases of intestines the drug can be administered in the form of a medicinal enema: To pour out 2-3 packages in 30-40 ml of boiled water of room temperature and by means of a cylinder pear to enter the received suspension into a rectum in 30-40 minutes after a cleansing enema once a day, a course of 10 days.

Features of use:

There are no precautionary measures.

Drug is allowed for use to women during the periods of pregnancy and breastfeeding. There are no special conditions of reception.

Drug does not influence ability to manage vehicles, mechanisms.

Side effects:

Are not established.

Interaction with other medicines:

At a concomitant use of Bifidumbacterium with vitamins (especially groups B) effect of drug amplifies. At reception of antibiotics the recommended interval between reception of an antibiotic and the drug Bifidumbacterium makes 3 – 4 hours.

Contraindications:

Inborn insufficiency of lactase. Glucose galactose absorption disturbance.

Overdose:

Cases of overdose were not observed.

Storage conditions:

Period of validity - 1 year. Drug is not suitable for use after a period of validity, at outward change, at absence or indistinct marking on primary packaging, at disturbance of tightness of primary packaging. To store at a temperature not above 10 °C. The lower bound of temperature is not limited. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Powder in a package from multilayer metalpolymeric material. On 10 or 30 packages on 5 doses of the application instruction in a pack from a cardboard.