Пиобактериофаг polyvalent cleared

General characteristics. Structure:

Active ingredient: 10 ml of mix of sterile filtrates of fagolizat of stafilokokk, streptococci, enterococci, a protea, клебсиелл (pneumonia and oxycurrent), pyocyanic and intestinal sticks in 1 bottle.

Preservative: 8 hydroxyquinolines of 0.0001 g/ml or 8 hydroxyquinolines sulfate - 0.0001 g/ml (in the form of sulfate hydroxyquinoline monohydrate).

Pharmacological properties:

Pharmacodynamics. Drug has ability to lyse specifically bacteria of Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli.

Indications to use:

Treatment and prevention of various forms of the pyoinflammatory and enteral diseases caused by bacteria of Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli:

— gastrointestinal diseases (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis);

— inflammatory diseases of newborns and children of early age (gastroenterocolitis, intestinal dysbiosis, omphalitis, pempigus, pyoderma, septicaemia and septicopyemia of various localization);

— surgical infections (suppurations of wounds, purulent damages of skin, burns, peritonitis, pleurisy, mastitis, osteomyelitis);

— urogenital infections (cystitis, pyelonephritis, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis);

— pyoinflammatory diseases of an ear, throat, nose, bosoms of a nose, oral cavity, throat, throat, lungs and pleura (otitis, quinsy, pharyngitis, stomatitis, periodontal disease, antritis, frontal sinusitis, pneumonia, pleurisy);

— posttraumatic conjunctivitis, keratoconjunctivitis, purulent helcoma and iridocyclitis;

— prevention of the intrahospital infections caused by bacteria of Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli.

Important condition of an effective phagotherapy is preliminary definition of a phagosensitivity of the activator.

Route of administration and doses:

Before use the bottle with a bacteriophage needs to be shaken up and seen. Drug has to be transparent and not contain a deposit.

Attention! At opacification not to use drug! Owing to the content in drug of a medium in which bacteria from the environment can develop, causing drug opacification, it is necessary to follow the following rules when opening a bottle:

— to carefully wash hands;

— to process a cap alcohol-containing solution; to remove a cap, without opening a stopper;

— not to put a stopper an internal surface on a table or other objects;

— not to leave a bottle open;

— to store the opened bottle only in the refrigerator.

When using small doses (2-8 drops) drug needs to be selected the sterile syringe of 0.5-1 ml.

Drug from the opened bottle at observance of storage conditions, above-mentioned rules and lack of opacification can be used during all period of validity.

Drug is used for intake (through a mouth), in the form of enemas, applications, irrigations, by introductions to cavities of wounds, vaginas, a uterus, a nose, nose bosoms, and also in the trained cavities: abscesses, belly, pleural, bladder, renal pelvis.

Inside drug is accepted on an empty stomach in 0.5-1 hour prior to meal.

The recommended drug dosages:

Treatment of pyoinflammatory diseases with the localized defeats has to be carried out at the same time as locally, and administration of drug inside.

In case of processing of a cavity of a suppurative focus chemical antiseptic agents before use of a bacteriophage it has to be washed out sterile 0.9% by chloride sodium solution.

At treatment of quinsy, pharyngitis, laryngitis drug 3 times a day on 10-20 ml use for rinsings of an oral cavity and throat, a course of treatment of 7-10 days.

At treatment of bronchitis, pneumonia drug is accepted inside by 3 times a day on 10-20 ml, and also apply in the form of aerosols and inhalations (without heating and use of ultrasound), a course of treatment of 15-20 days.

At treatment of otitis drug is used for washing and introduction to a tympanic cavity on 2-5 ml by 1-3 times a day. Course of treatment of 7-15 days.

At treatment of an inflammation of bosoms of a nose drug is used for washing of a nasal cavity, a nasopharynx and bosoms of a nose in a dose of 5-10 ml and by introductions to bosoms of 2-3 ml. The procedure is repeated daily once within 7-10 days. Besides, the drug is administered in a nasal cavity in the form of the turundas moistened with a bacteriophage in turn in each nasal course and left within 0,5-1 hours. The procedure 3 times a day repeat, a course of treatment of 7-15 days.

At treatment of stomatitis and a chronic periodontal disease drug 3-4 times a day in a dose use in the form of rinsings of an oral cavity 10-20 ml, and also introduction to paradontalny pockets of the turundas impregnated with a bacteriophage for 5-10 min., a course of treatment of 7-10 days.

At conjunctivitis and a keratoconjunctivitis drug is used on 2-3 drops of 4-5 times a day, a course of treatment of 5-7 days; at a purulent helcoma - on 4-5 drops a day within 7-10 days, at a purulent iridocyclitis - on 6-8 drops each 3 hours in combination with intake in therapeutic dosages within 7-10 days.

At abscess after opening and removal of purulent contents the drug is administered in quantity smaller, than the volume of remote pus daily once, a course of treatment of 7-10 days.

At peritonitis and pleurisy the drug is administered in the trained cavities - belly and pleural through drainage tubes daily once 20-70 ml, a course of treatment of 10-15 days.

At osteomyelitis the drug is administered in a wound cavity through turundas, drainages in number of 10-30 ml daily once, a course of treatment of 15-20 days.

At treatment of mastitis, suppurations of wounds and burns, drug is used in the form of irrigation, applications, bandages, by introductions to a drainage in a dose of 5-50 ml depending on the defeat center not less once a day, a course of treatment of 10-15 days.

At treatment of pyoinflammatory gynecologic diseases (suppurations of wounds, an endometritis, a vulvitis, bartholinitis, colpitis, salpingo-oophoritis) drug is used for irrigations, applications, enter into cavities of wounds, vaginas, a uterus 5-20 ml within 7-10 days once a day.

At cystitis, pyelonephritis, an urethritis drug is accepted inside in a therapeutic dose by 3 times a day in 1 hour prior to food within 10-20 days. If the cavity of a bladder or a renal pelvis are trained, the drug is administered through tsistosty or nefrosty 1-3 once a day on 20-50 ml in a bladder and 5-7 ml in a renal pelvis, a course of treatment of 7-15 days.

At a gastroenterocolitis, pancreatitis, cholecystitis, and also an intestinal dysbiosis the bacteriophage is accepted inside in age dosages by 3 times a day in 1 hour prior to food within 7-15 days (according to clinical indications). At pernicious vomiting drug is used in the form of high enemas by 2-3 times a day on 20-40 ml. At an intestinal dysbiosis drug can be used with drugs normoflor.

For prevention of vnutribolnichiy surgical infections drug use for processing of postoperative and svezheinfitsirovanny wounds in a dose 5-50 ml depending on the defeat center daily once within 5-7 days.

Use of drug for children till 1 year (including premature children). At a gastroenterocolitis, pneumonia and sepsis of newborns drug is used through a mouth by 2-3 times a day on 3-5 ml in 30 minutes prior to feeding. In cases of pernicious vomiting drug is used in the form of high enemas (through a colonic tube or a catheter) daily once in a dose of 5-10 ml. The combination rectal (in the form of high enemas) and oral administration of drug is possible. A course of treatment of 7-15 days (according to clinical indications). At the recurrent course of a disease perhaps repeated carrying out courses of treatment.

At treatment of an omphalitis, pyoderma, contaminated wounds the bacteriophage is applied in the form of applications on 5-10 ml by 2-3 times a day (the gauze napkin is moistened with a bacteriophage and impose on an umbilical wound or an affected area of skin) within 7-15 days.

For the purpose of prevention of developing of an intrahospital infection at newborn children the bacteriophage is applied according to epidemic indications inside on 3-5 ml by 3 times a day in 30 minutes prior to feeding during all term of stay in a hospital.

Features of use:

Use for children is possible according to the dosing mode.

Side effects:

Are not established.

Interaction with other medicines:

Use of drug does not exclude use of other antibacterial and antiinflammatory drugs.

Contraindications:

No.

Storage conditions:

Drug is stored (in the place, unavailable to children) and transported according to the joint venture 3.3.2.1248-03 at a temperature from 2 to 8 °C. Transportation is allowed at a temperature from 8 to 25 °C no more than 1 month. A period of validity - 2 years.

Issue conditions:

Without recipe

Packaging:

10 ml - bottles glass (4) - packs cardboard.
10 ml - bottles glass (10) - packs cardboard.
10 ml - bottles glass (4) - planimetric strip packagings (1) - packs cardboard.