Aminosol-Neo – the combined means for parenteral food filling shortage of amino acids and electrolytes in an optimum ratio.
Dosage form – solution for infusions of 10% or 15%: colourless or light yellow, or light brown liquid with transparent structure (on 500 or 1500 ml in glass bottles, in a cardboard pack of 1 or 10 bottles complete with the holder for a bottle).
Content of Aminosola-Neo active agents is 1000 ml of 10% or 15% of solution:
Energy value of solution: 10% – 400 kcal/l (1680 kJ/l), 15% – 600 kcal/l (2520 kJ/l), osmolarity 990 or 1505 ¼Äß¼/l respectively, pH – 5,5-6,5.
Auxiliary components: ice acetic acid, water for injections.
Besides, in 15% solution L-malic acid contains.
With care it is recommended to appoint Aminosol-Neo to patients with liver diseases, a diabetes mellitus, essential arterial hypertension, at sepsis.
Aminosol-Neo it is intended for intravenous (in/in) drop maintaining in one of the central veins.
The doctor appoints a dose individually, considering the patient's weight, weight of metabolic disturbance and the clinical need of an organism for amino acids.
It is necessary to apply only solution with transparent structure!
The recommended average daily dose for 10% of solution: from calculation for 10-20 ml on 1 kg of weight that corresponds to 1-2 g of amino acids on 1 kg of weight of the patient a day. Speed of infusion should not exceed 20-35 drops a minute that will provide receipt of 1 ml of solution on 1 kg of weight 60 minutes. The maximum daily dose – 20 ml on 1 kg of weight.
The recommended average daily dose for 15% of solution: on 6,7-13,3 ml on 1 kg of weight of the patient (1-2 g of amino acids on 1 kg a day). The maximum rate of administering – 0,67 ml on 1 kg of weight 60 minutes. The maximum daily dose – 13,3 ml on 1 kg.
As a rule, the daily dose for the patient weighing 70 kg has to correspond to 470-930 ml, and rate of administering – to 16 drops a minute.
Correction of a usual dose is recommended to patients with a renal failure: without dialysis – the dose of proteins on 1 kg of weight has to correspond to 0,6-1 g a day, at the patients who are on dialysis – on 1,2-2,7 g on 1 kg a day.
At a liver failure daily dosing has to be in limits of 0,8-1,1 g on 1 kg of weight.
Use of Aminosola-Neo can cause a lack of an organism of folic acid therefore the accompanying appointment is recommended to the patient of folates.
The arginine which is one of drug components can cause decrease in level of concentration of phosphorus and increase the content of potassium in plasma, especially at patients with a diabetes mellitus.
Not to allow development of a hyperpotassemia against the background of administration of arginine, the sick diabetes mellitus (1 and 2 types) and to patients in stressful states recommends to appoint administration of insulin along with Aminosolom-Neo.
Before administration of drug it is necessary to be convinced of tightness of a bottle!
Not to allow uncontrollable addition to Aminosolu-Neo of other medicines.
At simultaneous use of solution of drug:
Pharmaceutical we will combine with ampicillin, amikacin, tsefotaksimy, doxycycline, tseftriaksony, erythromycin, gentamycin, chloramphenicol, netilmitsiny, penicillin, tetracycline, clindamycin, piperatsilliny, Vancomycinum, Tobramycinum, cyclophosphamide, Aminophyllinum, Cimetidinum, Cytarabinum, dopamine, phytomenadionum, famotidine, ftoruratsily, folic acid, heparin, Chlorpromazinum, furosemide, insulin, metildopy, calcium a gluconate, lidocaine, Metoclopramidum, nizatidiny, a methotrexate, Methylprednisolonum, morphine, Norepinephrinum, ranitidine, propranolol, Riboflavinum, digoxin.
Because of availability of Aminosol-Neo arginine it is impossible to combine using sodium thiopental.
To store in the place protected from light at a temperature of 15-25 °C. To protect from children.
Period of validity – 2 years.
According to researches, the women drinking several glasses of beer or wine in a week have the increased risk to develop breast cancer.
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