UPSA aspirin

UPSA aspirin – the non-steroidal anti-inflammatory drug used for stopping of a pain syndrome and decrease in body temperature at inflammatory or infectious diseases.

Form of release and structure

UPSA aspirin is produced in the form of flat sparkling tablets of white color (on 4 tablets in a strip).

Contains in 1 tablet:

• Acetylsalicylic acid – 500 mg;
• Excipients: sodium carbonate anhydrous, citric acid anhydrous, sodium citrate anhydrous, Natrii hydrocarbonas, кросповидон, aspartame, fragrance orange natural, povidone.

Indications to use

UPSA aspirin has analgeziruyushchy, antiinflammatory and febrifugal effect. Advantage of a soluble form of drug in comparison with traditional acetylsalicylic acid is fuller and bystry absorption of active ingredient and its best portability. Also drug reduces a thrombogenesis and aggregation of thrombocytes, at the same time the antiagregantny effect remains within a week after a single dose.

UPSA aspirin is applied:

• Moderately or poorly expressed pain syndrome of various origin, including head and a dentagra, muscular and joint pains, neuralgia, migraine, a chest radicular syndrome, альгодисменорею;
• The increased temperature at catarrhal or other infectious and inflammatory diseases.

Contraindications

• Digestive tract erosive cankers in an aggravation phase, gastrointestinal bleeding;
• Portal hypertensia;
• "Aspirinovy" asthma;
• The stratified aortic aneurysm;
• Fenilketonuriya;
• Hemorrhagic diathesis, including hemophilia, a teleangiectasia, an angiohemophilia, thrombocytopenia, a prothrombinopenia, a Werlhof's disease;
• Deficit glyukozo-6-fosfatdegidrogenazy;
• Hypersensitivity to components of UPSA Aspirin or other non-steroidal anti-inflammatory drugs;
• The expressed abnormal liver functions and kidneys;
• Deficit of vitamin K.

It is authorized to accept drug only in the II trimester of pregnancy, at inclusion in the lactation period breastfeeding is recommended to be stopped. UPSA aspirin is not applied at children's age up to 15 years because of risk of development of a syndrome to Reja.

Medicine should be taken with caution at an uratny nephrolithiasis, a hyperuricemia, dekompensirovanny heart failure and a peptic ulcer of a stomach and duodenum in the anamnesis. At use of UPSA Aspirin it is necessary to consider that it can become the reason of a bad attack of gout at the existing predisposition.

Route of administration and dosage

Children can take UPSA aspirin 15 years and the adult on 1 tablet to 6 times a day with an interval between receptions not less than 4 hours are more senior. Before use the tablet should be dissolved in a glass of water or juice of room temperature.

At the beginning of a disease at severe pains and high temperature it is possible to accept 2 tablets at the same time, but no more than 6 pieces a day, to elderly people – no more than 4. As an antipyretic UPSA Aspirin is taken by 3 days as analgeziruyushchy – up to 5 days.

At overdose at first symptoms of excitement of the central nervous system, vomiting, a severe headache, dizziness, nausea, decrease in auditory acuity, a vision disorder and strengthening of breath then respiratory insufficiency, oppression of consciousness can develop up to a coma and disturbance of water and electrolytic exchange can be shown.

It is necessary to be careful at combined use of UPSA Aspirin with glucocorticoid means and ethanol as the last increase effect of acetylsalicylic acid by a mucous membrane of digestive tract, increasing thereby risk of development of gastrointestinal bleedings.

Side effects

In the recommended doses UPSA Aspirin usually is transferred well. Seldom at administration of drug the following disturbances can develop:

• Skin rash, "aspirinovy triad", bronchospasm and Quincke's edema;
• Renal failure;
• Nasal bleeding, increase in time of coagulability of blood, bleeding of gums;
• Nausea, loss of appetite, vomiting, gastrointestinal bleedings, pains in epigastric area, diarrhea;
• Thrombocytopenia, leukopenia, anemia, hyperbilirubinemia.

At emergence of undesirable effects reception of UPSA Aspirin should be stopped.

Special instructions

During treatment it is necessary to consider that the acetylsalicylic acid which is a part of drug increases toxicity of a methotrexate, and also effects of other non-steroidal anti-inflammatory drugs, opioid analgetics, peroral hypoglycemic drugs, indirect anticoagulants, heparin, streptocides, trombolitik and inhibitors of aggregation of thrombocytes, triiodothyronine.

Analogs

Analogs of UPSA Aspirin are:

• On active agent: Taspir, Aspinat, Aspitrin, Fluspirin, Atssbirin, Aspivatrin, Aspirin, Asprovit, Acetylsalicylic acid, Nekstrim Fast, Upsarin Upsa;
• On the action mechanism: Aspagel, Kofitsil-plus, Akvatsitramon, Salicylamidum, Tsitrapak, Aspivit, Atselizin, Citramonum P, Alka-Zelttser, Alka-prim, Parkotset, Atsepar, Angrikaps.

Terms and storage conditions

Drug is released without recipe of the doctor. To store at a temperature up to 30 °C.

Period of validity – 3 years.