Liver steatosis
Contents:
Description:
Liver steatosis (fatty hepatosis, fatty infiltration of a liver) — the most widespread hepatosis at which in hepatic cells there is a fat accumulation. Accumulation of fat can be reaction of a liver to various toxic influences, sometimes this process is connected with some diseases and morbid conditions of an organism.
Liver Steatosis symptoms:
Usually the steatosis is characterized by the stable, not progressing current. If inflammatory process joins fatty infiltration, that is develops steatogepatit, then the disease often progresses with formation of fibrosis of a liver (at 30-40% of patients) and cirrhosis (approximately at 10%). It should be noted a possibility of involution of not alcoholic fatty alcoholic disease against the background of weight reduction. At most of patients the symptoms characteristic of liver diseases, no. Sometimes there are complaints to weight and unpleasant feelings in the right upper quadrant of a stomach amplifying at the movement, fatigue, weakness, nausea. Quite often the disease is diagnosed accidentally, at ultrasound examination of a liver when its increase and hyper echogenicity or "brightness" of tissue of liver owing to diffusion fatty infiltration is found.
Liver Steatosis reasons:
Are the main reasons for a steatosis of a liver:
Disbolism — a diabetes mellitus 2 types, obesity, a gipertriglitseridemiya;
Action of toxic factors — alcohol, some toxic substances, medicines;
Unbalanced food (overeating, starvation, lack of protein of food);
Chronic diseases of the alimentary system with a syndrome of the broken absorption, etc.;
Cushing's syndrome;
myxedema.
The fatty infiltration of a liver which is not connected with effect of alcohol or other toxic substances is called primary or not alcoholic steatosis (not alcoholic fatty alcoholic disease of a liver). Thus, not always damage of a liver are connected with action of toxic factors (alcohol, medicines).
Today prevalence of not alcoholic fatty alcoholic disease of a liver is very considerable. Approximately at a quarter of the population of the developed countries the liver steatosis comes to light, and at 3,5-11% — not alcoholic steatogepatit, including cirrhosis. Not alcoholic fatty alcoholic disease of a liver is diagnosed for corpulent people much more more often than at persons with a normal weight.
Risk factors of a severe disease:
- the age is more senior than 45 years
- pathological obesity
- diabetes mellitus 2 types
- genetic factors
- female
Treatment of the Steatosis of a liver:
Treatment is directed first of all to the steatosis reason (an alcohol exception, regulation of carbohydrate metabolism, etc.). The mode of process has to be in full swing sparing (bed in the acute period, further — with restriction of exercise and mental stresses). During remissions the easy physical exercises increasing a metabolic cost lead to reduction of dystrophic changes. The leading value belongs to a dietotherapy. Food has to be full, contain enough proteins (100 — 120 g/days), vitamins and limited amount of fats. The products enriched with lipotropic factors (cottage cheese, buckwheat and oat porridges, yeast) are recommended; at the general obesity limit carbohydrates. Medicinal treatment includes long (up to 10 — 12 months) use of lipotropic means — methionine, lipocainum, B12 vitamin (100 — 200 mkg intramusculary), lipoic acid, lipamidum, Essentiale (inside and intravenously). Appoint also folic acid on 15 — 50 mg a day, anabolic steroids (methandrostenolone and retabolil). The initial daily dose of the methandrostenolone appointed inside has to make not less than 20 mg, retabolil is entered on 25 — 50 mg once into 2 — 3 weeks. Are shown Butamidum and глибутид (Adebitum), glycogen stocks stimulating synthesis of albumine and increasing in a liver. At aggravations treatment is carried out in a hospital, then it is out-patient.
