Tavanik

Tavanik – the synthetic antibacterial medicine applied at treatment of a wide range of diseases.

Pharmacological action of Tavanik

Active component of Tavanik – levofloxacin (from group of ftorkhinolon), has antibacterial effect of a wide range and shows activity concerning the majority of strains of microorganisms.

At use Tavanik causes considerable morphological changes both in cytoplasm, and in membranes and cell walls of microbic cells.

Cross resistance between drug Tavanik and other antimicrobic means usually is not observed that it is connected with features of the mechanism of effect of active component.

Release form

Drug Tavanik is produced in a look:

• The oblong light pink tablets containing 250 and 500 mg of a levofloksatsin. On 3, 5, 7 and 10 pieces in blisters;
• Chartreuse transparent solution for infusions, in bottles on 100 ml containing 500 mg of a levofloksatsin.

Tavanik's analogs

Medicines belong to Tavanik's analogs containing the same active ingredient: Glevo, Ivatsin, Levotek, Levofloksatsin, Maklevo, Signitsef, Tanflomed, Lebel, Fleksid, Remedia, Elefloks.

Besides, there is a number of the analogs of Tavanik having similar therapeutic effect. Drugs in various dosage forms concern to them: Abaktal, Basidzhen, Zanotsin, Zofloks, Ifitsipro, Kvintor, Dzheofloks, Normaks, Lofoks, Ofloks, Ofloksatsin, Pefloksabol, Factive and some other.

Indications to Tavanik's use

Tavanik according to the instruction appoint at treatment of the bacterial infections caused by microorganisms, sensitive to active component (levofloksatsin), namely at:

• Exacerbation of chronic bronchitis;
• Infections of an abdominal cavity;
• Acute sinusitis;
• Uncomplicated infections of urinary tract;
• Infections of integuments and soft tissues;
• Community-acquired pneumonia;
• Chronic bacterial prostatitis;
• The complicated infections of urinary tract, including pyelonephritis.

Besides, Tavanik's use is effective as a part of complex treatment of tuberculosis (in drug resistant forms).

Contraindications

According to the instruction Tavanik it is contraindicated to apply in the following cases:

• At children's and teenage age up to 18 years (that is connected with the continuing growth of a skeleton);
• At damage of the sinews tied with reception of ftorkhinolon in the anamnesis;
• At epilepsy;
• In the period of a lactation;
• At pregnancy;
• At hypersensitivity to a levofloksatsin or auxiliary components of Tavanik.

As a rule, Tavanik appoint with care:

• At predisposition to development of spasms;
• At a pseudoparalytic myasthenia;
• At deficit glyukozo-6-fosfatdegidrogenazy (to avoid risk of development of hemolitic reactions);
• Against the background of a diabetes mellitus;
• At renal failures;
• To people at advanced age.

Tavanik route of administration

As a rule, Tavanik (depending on a dosage form) accept inside or enter intravenously up to two times a day on 250 or 500 mg.

As meal does not influence Tavanik's efficiency, it is possible to accept drug as between meals at any time, and during food. However at combined use of Tavanik with antiacid drugs it is necessary to observe an interval not less than 2 hours between them.

Duration of treatment and the accepted Tavanik's dosage according to the instruction depend on a disease.

At treatment of acute sinusitis and community-acquired pneumonia take 1 pill of Tavanik (500 mg) from 10 to 14 days once a day.

Tavanik's use at an exacerbation of chronic bronchitis is shown in the same dosage, however duration of treatment makes from a week to 10 days.

For treatment of uncomplicated infections of urinary tract appoint for three days on 250 mg of drug. At the complicated infections treatment longer (up to 10 days).

Treatment of prostatitis it is necessary to spend not less than 28 days in the dosage of 500 mg accepted in one or two receptions.

At treatment of infections of integuments and soft tissues, an abdominal cavity and bacteremia Tavanik's use is shown for 1-2 weeks on 500 mg. At the same time treatment of infections of an abdominal cavity should be carried out along with reception of the antibacterial agents having effect on anaerobic flora.

At antitubercular therapy (in drug resistant forms of a disease) 0,5-1 g of Tavanik accept for three months.

The most probable symptoms of overdose by Tavanik according to the instruction are:

• Dizziness;
• Consciousness disturbances (in certain cases – confusion of consciousness);
• Spasms.

Medicinal interaction of Tavanik

Extra care should be observed at simultaneous use of Tavanik with:

• The drugs containing bivalent or trivalent cations (for example, antiacid means which contain magnesium or aluminum, iron salts);
• Sukralfat;
• Indirect anticoagulants;
• The medicines breaking renal canalicular secretion of a levofloksatsin (for example, пробеницид and Cimetidinum);
• Drugs which extend QT interval (for example, tricyclic antidepressants, antiarrhythmic drugs of the class IA and III, macroleads);
• Glucocorticosteroids.

Side effects of Tavanik

Most often at Tavanik's reception the following undesirable effects according to reviews develop:

• Sleeplessness;
• Headache;
• Diarrhea, nausea and vomiting;
• Dizziness.

Slightly less often Tavanik according to reviews leads to development:

• Leukopenias, eosinophilias;
• Drowsiness, tremor, dysgeusia;
• Vertigo;
• Feelings of concern, confusion of consciousness;
• To asthma;
• Abdominal pains, dyspepsias;
• To rash, itch and urticaria;
• Arthralgias, mialgiya;
• Anorexias.

Seldom and extremely seldom at the carried-out therapy Tavanik according to reviews causes:

• Sinus tachycardia, lowering of arterial pressure;
• Neutropenia, thrombocytopenia;
• Paresthesia, spasms;
• Vision disorder;
• Ring in ears;
• Mental disturbances, nightmares, depression, agitation, sleep disorders;
• Damages of sinews, muscular weakness;
• Hypoglycemia;
• Pyrexia.

Also according to reviews Tavanik can lead to disturbances from a liver, an urinary system and biliary tract.

Storage conditions

Tavanik treats antibacterial agents with a period of storage of 5 years.