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Adiuretin SD

Adiuretin SD – vazopressinopodobny means.

Form of release and structure

  • Solution for injections (on 1 ml in ampoules, in packaging of 5 ampoules);
  • Drops nasal (on 5 ml in bottles droppers, in packaging 1 bottle).

Active ingredient: desmopressin acetate:

  • 1 ml of solution for injections – 4 mkg;
  • 1 ml of drops nasal – 100 mkg (in 1 drop – 5 mkg).

Indications to use

For injection solution:

  • Not diabetes mellitus (diagnosis and treatment);
  • Angiohemophilia;
  • Hemophilia;
  • Acute polyuria after hypophysis operations.

For nasal drops:

  • Bed wetting;
  • Not diabetes mellitus;
  • Research of concentration ability of kidneys.



  • Anury;
  • Delay of liquid of various etiology, including at chronic heart failure;
  • The states which are followed by the lowered relative osmotic density of a blood plasma including a psychogenic and usual polydipsia;
  • Hypersensitivity to drug components.

Route of administration and dosage

Solution for injections
In this dosage form Adiuretin SD enter subcutaneously, intramusculary or intravenously.

The recommended doses:

  • Not diabetes mellitus – on 0,025 mkg/kg (2000-4000 mkg for adults and 400 mkg for children) 2 times a day (in the morning and in the evening). Solution doses enter more than 1 ml in the form of slow intravenous drop infusion;
  • Hemophilia And yes angiohemophilia: adults and children are more senior than 11 months – on 0,3 mkg/kg in the form of intravenous infusion (in 50 ml of solution of sodium of chloride of 0,9%) within 15-30 min. To children to 11-month age at these diseases drug is not appointed.

At not diabetes mellitus in the form of solution for injections Adiuretin appoint in case of impossibility of intranasal use of drug.

Drops are nasal
In this dosage form Adiuretin is applied intranazalno.

The recommended doses:

  • Bed wetting: till 2-10 drops for the night;
  • Not diabetes mellitus: on 1-3 drops 2-3 times a day;
  • Acute central polyuria: on 2 drops. If within 1 hour normalization of balance (intake of liquid in the form of infusion and a diuresis) does not happen, it is recommended to transfer the patient to injection administration of drug (more often intravenous);
  • At a research of concentration ability of kidneys: the usual dose – 3 drops (15 mkg), to children is more senior than 1 year – on 2-3 drops (10-15 mkg) before test. Right after a drug instillation the patient needs to empty a bladder, and during test and within 4 hours after its termination (in total about 8 hours) to limit receipt in a liquid organism. Within the next 4 hours of use of drug urine samples for osmolarity definition collect each hour. Testing needs to be repeated if in test result decrease in concentration ability of kidneys is established.

Side effects

At Adiuretin's use SD is possible development of the following side effects: a headache, spastic abdominal pains, nausea, vomiting, the increased perspiration, the complicated urination, and also irritation of a mucous membrane of a nose (at use of drops nasal).

Special instructions

The nephrologist has to conduct a research of concentration ability of kidneys.

At children 1 years the test with Adiuretin's use are younger SD carry out in exceptional cases. It is caused by the fact that the drug used in high doses at this age can lead to development of spasms and other mental and neurologic symptoms.

In case of test at children till 1 year during time of collecting urine it is necessary to exclude liquid reception completely.

Medicinal interaction

At simultaneous use of a dopamine mutual strengthening of pressor effect is noted. In need of purpose of this combination treatment should be carried out under careful control of a condition of the patient.

Terms and storage conditions

To store in protected from light, the place, unavailable to children, at a temperature of 5-15 ºС.

Period of validity – 2 years.

Whether you know that:

The liver is the heaviest body in our body. Its average weight makes 1,5 kg.