Diklo-F

Diklo-F – non-steroidal anti-inflammatory drug (NPVS) for topical administration in ophthalmology.

Form of release and structure

Dosage form – eye drops of 0,1%: transparent solution from colourless till light yellow color (on 5 ml in dark glass bottles complete with a dropper or in bottles droppers, in a cardboard pack 1 bottle).

Active ingredient: sodium diclofenac, in 1 ml – 1 mg.

Additional substances: polioksit the 35th castor oil, boric acid, трометамин, dinatrium эдетат, water injection, a benzalkoniya chloride.

Indications to use

• Suppression of a miosis during surgical intervention concerning a cataract;
• Treatment of noninfectious conjunctivitis;
• Treatment and prevention of inflammatory processes after operations on an eyeglobe;
• Treatment and prevention of a posttraumatic inflammation at not getting and getting eyeglobe wounds (in a combination with local antibacterial drugs);
• Prevention of cystous hypostasis of a makula after surgical intervention concerning a cataract.

Contraindications

Absolute:

• Aggravation of erosive and ulcer process in digestive tract;
• Disturbance of a hemopoiesis of unspecified genesis;
• Hypersensitivity to drug components, acetylsalicylic acid or other NPVS.

Relative (diseases/states at which Diklo-F it is necessary to apply with care because of probability of development of complications):

• Epithelial herpetic keratitis, including in the anamnesis;
• The diseases causing blood coagulation disturbances (including tendency to bleedings, lengthening of a bleeding time, hemophilia);
• Advanced age.

Data on safety of use Diklo-F at children's age, during pregnancy and a lactation is not present therefore drug can be appointed only in cases when the estimated advantage exceeds possible risks.

Route of administration and dosage

Diklo-F it is necessary to drip in a conjunctival sac of the affected eye.

• Inhibition of an intraoperative miosis: dig in 4 times within 2 hours before bucketed operation of 30 minutes;
• Prevention of cystous hypostasis of a makula: on 1 drop 3-4 times a day within 2 weeks after surgical intervention;
• Other indications: on 1 drop 3-4 times a day depending on weight of a course of a disease. Duration of treatment is 1-2 weeks.

Side effects

• Organ of sight: seldom – an illegibility of visual perception (right after instillation), burning, an iritis, opacification of a cornea;
• Allergic reactions: a hyperemia, an itch in eyes, a fever, fever, a photosensitization, urticaria or other skin rash (including erythematic), a mnogoformny exudative erythema, a Quincke's disease of the person;
• Digestive tract: nausea, vomiting.

Special instructions

The patients using contact lenses need to remove them in 5 minutes prior to an instillation of drug and to establish not earlier than in 15 minutes.

During use Diklo-F it is necessary to be careful not to concern an eye pipette tip. After each instillation it is necessary to close a bottle densely.

During treatment it is recommended to refrain from control of vehicles and performance of potentially dangerous works requiring visual acuity, special attention and speed of reactions.

Medicinal interaction

• The methotrexate, diflunizat, sulphonylurea drugs, other NPVS, including acetylsalicylic acid in high doses (3 g and more in days): there is a risk of development of bleeding from digestive tract;
• Lithium drugs, indirect anticoagulants, digitoxin: their effect amplifies.

If necessary along with Diklo-F other medicines for topical administration in ophthalmology can be appointed (including glucocorticosteroids), however between instillations it is necessary to observe at least 5-minute intervals.

Terms and storage conditions

To store at a temperature no more than 30 °C in the place, unavailable to children, protected from light. Not to freeze.

Period of validity – 2 years, after the first opening of a bottle – 1 month.