Application instruction:
Fraksiparin (the international name – Nadroparin of calcium) treats group of direct anticoagulants which have antitrombotichesky effect. Drug improves blood circulation and normalizes the content of cholesterol.
Fraksiparin was widely used as effective drug for treatment of a thromboembolism and its complications.
The main active ingredient – надропарин calcium 5700-9500 ME.
Auxiliary components: calcium hydroxide, chlorous acid, the purified water.
Fraksiparin is issued in the form of solution for injections of hypodermic introduction, in ampoules on 1 ml.
Fraksiparin is created on the basis of the low-molecular heparin created in the course of a depolymerization. Drug strengthens effect of antithrombin and accelerates process of transition of a prothrombin to thrombin.
Fraksiparin has good responses as medicine with bystry and long medical action. Drug normalizes the maintenance of lipoproteins in blood, has an antiinflammatory and immunodepressive effect.
After administration of solution of Fraksiparin within 3-4 hours 100% absorbability are reached. In a liver several metabolites of inactive action are formed. Drug is removed from an organism through kidneys with urine.
Before an initiation of treatment it is necessary to carry out diagnosis of functioning of a liver and kidneys, to check the content of cholesterol and level of coagulability of blood. For elderly patients (of 70 years) drug has to be appointed in the minimum dosage.
Fraksiparin is appointed for treatment of disturbances of coagulability of blood, a thromboembolism, stenocardia, a myocardial infarction, blood circulation disturbances.
Fraksiparin received positive reviews as effective drug for prevention of tromboembolic episodes (respiratory insufficiency, infections, heart failure) after operations (the general and orthopedic surgery).
Contraindications to Fraksiparin's appointment are hypersensitivity and intolerance of components of drug, internal bleedings, a pericardis, pregnancy and the period of breastfeeding, a vasculitis, a hypertension, comas, diseases of a nervous system, a peptic ulcer, the period after a spinal puncture, a serious illness of the alimentary system.
With care drug is appointed at a liver and renal failure, a diabetes mellitus and at advanced age.
According to the instruction Fraksiparin enter into hypodermic cellulose in a stomach and support a skin fold during the entire period of administration of solution. The drug is administered to the patient who is in a prone position, holding a needle perpendicularly.
At a thromboembolism the drug is administered on 0,3-0,5 ml of 1 times a day. Before carrying out surgical intervention enter 0,4 ml of solution.
The course of treatment makes 10-14 days during which 2 times a day enter 0,5 ml of Fraksiparin.
According to Fraksiparin's instruction the dosage when carrying out orthopedic operation depends on the body weight of the patient:
After end of a course of treatment by Fraksiparin (according to the recommendation of the attending physician) preventive therapy can be appointed peroral anticoagulants.
Fraksiparin can cause internal bleedings and hemorrhages, disturbances of functioning of adrenal glands, thrombocytopenia, anaphylactic reactions.
At a long course of treatment allergic reactions – skin rash, a small tortoiseshell, asthma, a skin necrosis, fever can appear.
Name of drug
Price
Drugstore
Fraksiparin solution for инъ 2.85tys. ME 0.3ml шпр No. 10, Glaxo Wellcome Production
2719 rub.
Fraksiparin solution for инъ 5,7tys. ME 0,6ml шпр No. 10, Glaxo Wellcome Production
4292 rub.
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