Fungoterbin

Structure

Fungoterbin of a tablet: each tablet contains 250 mg of a terbinafin. The used excipients: the benzoic acid, cellulose microcrystallic, aerosil, коллидон CL-M, magnesium stearate, коллидон 30.

Fungoterbin cream: 1 g of cream contains 0,01g a terbinafin of a hydrochloride.

The used excipients: the benzoic acid, cellulose microcrystallic, magnesium stearate, коллидон CL-M, aerosil, коллидон 30.

Pharmacological properties

Active agent of drug - тербинафин which is to derivatives of allylamine and has broad antifungal action. Drug is active in relation to dermatophytes: Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, Microsporum canis, Trichophyton rubrum, Trichophyton verrucosum, Trichophyton violaceum. Renders fungicidal effect concerning mold mushrooms (Aspergillus, Scopulariopsis brevicaulis Cladosporium), and also some species of dimorphous mushrooms.

As well as the majority of analogs Fungoterbin does not influence synthesis of hormones.

Indications to Fungoterbin's use

• onychomycoses;

• therapy of dermatomycoses of extremities and trunk;

• mycoses (microsporia, trichophytosis);

• the candidiases of mucous membranes and skin caused by mushrooms of a type of Candida.

Fungoterbin's dosage and application instruction

Duration of a therapeutic course and dosage are established individually, according to indications of weight of course of a disease and extent of localization of process.

To adult patients about 1 tablet (250 mg) after food, is appointed once a day. In the presence of a renal or liver failure the dosage makes 1/2 tablets, once a day.

At mycoses of integuments, the course of treatment recommended by Fungoterbin's instruction makes 2-6 weeks.

At onychomycoses: The recommended course of therapy makes 6-12 weeks.

The stable clinical effect is fixed after several months after completion of therapy.

Cream Fungoterbin is applied on a skin surface 1-2 times a day. It is necessary to clear the site of the affected skin before putting drug on it. Cream is applied on an affected area with a thin layer with easy rubbing in.

Average duration of therapy:

• At a dermotoksikoza of shins or trunks: Put 1 time within 1 week;

• At a dermatomycosis: Put 1 time within one week;

• At multi-colored herpes: 1-2 times a day within 2 weeks;

• At skin candidiasis: 1-2 times a day within 1-2 weeks.

Drug use, for children since two years is admissible. At body weight less than 20 kilograms – 1/4 таб., from 20 kg to 40 kg – 1/2 таб., over 40 kg – one tablet a day. About use by patients Fungoterbina of responses is younger than 2 years it was not received.

Fungoterbin's contraindications

Individual intolerance of a terbinafin or any other auxiliary drug of Fungoterbin who is a part.

It is necessary to take Fungoterbin with caution, at:

• alcoholism;

• tumors;

• blood diseases;

• pathologies of vessels;

• age up to 2 years;

• the diseases connected with a metabolism.

Special instructions

At irregular use or the early end of therapy, there is a risk of development of a recurrence. If after 2 weeks of treatment Fungoterbin's analogs do not observe positive dynamics, it is necessary to carry out the analysis of definition of an infestant repeatedly.

According to clinical responses фунготербин it is not effective at multi-colored herpes. During therapy and on the end of treatment it is necessary to carry out anti-fungal processing of footwear and a sock.

Pregnancy and lactation

Enough reviews of Fungoterbin's use at pregnancy therefore use of drug for pregnant women is not recommended was not received. It was established that there is a hit of drug in breast milk therefore at Fungoterbin's appointment of the nursing mother it is necessary to stop chest feeding.

Side effects of Fungoterbin

Possible side effects of Fungoterbin have slight character and last short time. At oral administration the following side effects can be observed:

• dyspepsia, loss of appetite, abdominal pain, diarrhea, nausea;

• joint pains, muscle pains;

• neutropenia, thrombocytopenia, lymphopenia.

Manifestations of allergic reactions are possible: skin rash in the form of blisters, spots, a toxic epidermal necrolysis, anaphylactoid reactions.

Storage

To store in protected from light, the place dry, unavailable to children.

Period of storage of Fungoterbin

2 years.