Kanefron of N

Kanefron of N – the drug of a plant origin used at treatment of diseases of urinary tract and kidneys.

Form of release and structure

Kanefron N release in the following dosage forms:

• Dragee: orange, biconvex, round, with a smooth surface (on 20 pieces in blister strip packagings, on 3 or 6 packagings in a cardboard pack);
• Solution for intake: yellowish-brown, slightly muddy or transparent, with a fragrant smell; in the course of storage the small deposit can drop out (on 50 or 100 ml in bottles with the drop portioning device, on 1 bottle in a cardboard pack).

Active agents are a part of 1 dragee (in the form of the crushed medicinal vegetable raw materials):

• Centaury (grass) – 18 mg;
• Lyubistok medicinal (roots) – 18 mg;
• Rosemary (leaves) – 18 mg.

Auxiliary components: corn starch – 15 mg, povidone – 9 mg, monohydrate of lactose – 45 mg, colloid silicon dioxide – 5,5 mg.

Structure of a cover: ferrous oxide red – 0,049 mg, Riboflavinum of E 101 - 0,243 mg, calcium carbonate – 17,222 mg, a dextrose – 0,972 mg, corn starch – 2,5 mg, the modified corn starch – 2,14 mg, glycolic mountain wax – 0,075 mg, povidone – 0,103 mg, castor oil – 0,025 mg, sucrose – 57,182 mg, shellac – 0,615 mg, talc – 43,541 mg, titanium dioxide – 0,333 mg.

Active agents are a part of 100 mg of solution for intake (in the form of aqueous-alcoholic medicinal vegetable raw materials extract – 29 mg):

• Centaury (grass) – 0,6 mg;
• Lyubistok medicinal (roots) – 0,6 mg;
• Rosemary (leaves) – 0,6 mg.

Auxiliary component: the purified water – 71 mg.

Indications to use

Kanefron N appoint along with other drugs at treatment of the following diseases:

• Persistent infections of kidneys (pyelonephritis) and bladder (cystitis);
• Noninfectious chronic inflammations of kidneys (intersticial nephrite, glomerulonephritis).

Also drug is used as the means interfering formation of urinary stones (including states after removal of urinary stones).

Contraindications

• Peptic ulcer of a stomach and duodenum in an aggravation stage;
• Age till 1 year (solution for intake) or 6 years (dragee);
• Hypersensitivity to drug components.

Additional contraindications to Kanefron's use N are:

• Dragee: insufficiency of lactase, glyukozo-galaktozny malabsorption, lactose intolerance, intolerance of fructose, deficit of invertase/isomaltase;
• Solution for intake: alcoholism (including after antialcoholic therapy).

Because of the contained ethanol Kanefron the N in the form of solution for intake should be taken with caution the patient with liver diseases, craniocereberal injuries, brain diseases, and also to children (treatment is possible only after consultation with the doctor).

The reproaching and pregnant women Kanefron of N in any dosage form can accept in strict accordance with recommendations about use only on doctor's orders and after ratio assessment advantage/risk.

Route of administration and dosage

Kanefron N accept inside, – do not chew a dragee and wash down with water, – wash down solution for intake with water or part with a small amount of water (for mitigation of bitter taste children can dissolve drug with other liquids). Solution before reception should be shaken up.

As a rule, drug is appointed in a single dose:

• Adults: 2 dragees or 50 drops of solution;
• Children of school age: 1 dragees or 25 drops of solution;
• Children of preschool age (of 1 year): 15 drops of solution.

Frequency rate of reception – 3 times a day.

After weakening of symptoms of a disease therapy should be continued for 14-28 days.

During Kanefron's reception the N is recommended to drink liquid in bigger quantity.

Side effects

During Kanefron's reception N can arise the following side effects:

• Disorders of digestive tract (in the form of vomiting, nausea, diarrhea);
• Allergic reactions (at development of symptoms of allergic reaction administration of drug needs to be stopped).

Special instructions

At the hypostases connected with renal failures or hearts, the use of a large amount of liquid is contraindicated.

At functional disturbances of kidneys Kanefron the N should not appoint as monotherapy. At the inflammatory nature of diseases of kidneys it is necessary to see a doctor behind consultation.

In the presence of urodynias, blood in urine or at an acute ischuria should see a doctor urgently.

The acquired carbohydrates which are contained in 1 dragee make less than 0,04 "grain units" (GU).

At Kanefron's storage N in the form of solution for intake loss of an insignificant deposit or emergence of easy opacification is possible that does not influence efficiency of drug.

Content of alcohol in solution for intake in the volume relation makes 16-19,5%. During reception of this dosage form of Kanefron of N it is necessary to be careful at control of motor transport and when performing other potentially dangerous types of activity demanding high concentration of attention and bystry psychomotor reactions.

Medicinal interaction

Kanefron's combination of N in any dosage form with antibacterial drugs is possible and reasonable.

At the moment interactions with other medicines are unknown.

Terms and storage conditions

To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.

Period of validity – 3 years.

After opening of a bottle Kanefron's solution of N can be accepted within 6 months.