Ornisid

Ornisid – medicine of antiprotozoan action with antibacterial resistance.

Form of release and structure

• Tablets, coated, 0,25 g: biconvex, round, with risky on one of the parties, a cover from almost white till white color (on 10 pieces in blisters, 2 blisters in a pack cardboard);
• Tablets vaginal 0,5 g: biconvex, oval, with the pointed end, from almost white till white color (on 3 pieces in blisters, 1 blister in a pack cardboard).

Contains in 1 tablet:

• Active ingredient: орнидазол – 0,25 g;
• Auxiliary components: potato starch, magnesium stearate, hydroxymethylethyl cellulose, cellulose microcrystallic;
• Cover: talc, gipromelloz, titanium dioxide.

Contains in 1 vaginal tablet:

• Active ingredient: орнидазол – 0,5 g;
• Auxiliary components: lactose, calcium dihydrophosphate, citric acid anhydrous, magnesium stearate, polyvinylpirrolidone, starch corn, starch gelated.

Indications to use

Tablets, coated

• Lambliasis;
• Amebiasis, abenteric amebiasis (including amoebic abscess of a liver), amoebic dysentery;
• Trichomoniasis;
• Prevention of anaerobic infections at surgery in gynecology and operative measures on a colon.

Tablets are vaginal

• Urogenital trichomoniasis;
• The nonspecific vaginita of various etiology confirmed with data of clinical and microbiological trials.

Contraindications

• Organic lesions of the central nervous system, including epilepsy;
• Pregnancy (I trimester);
• Period of breastfeeding (lactation);
• Hypersensitivity to Ornisid's components and derivatives of a nitroimidazole.

Additional contraindications for vaginal tablets:

• Leukopenia;
• The broken coordination of movements;
• Liver failure (at purpose of high doses).

It is required to apply with care of a tablet vaginal in the presence in the anamnesis of data on a leukopenia, and also to pregnant women in II and III trimesters.

Route of administration and dosage

Tablets, coated
Pill is taken inside.

The recommended dosing depending on a disease:

• Trichomoniasis: adult – 0,5 g 2 times a day, a course – 5 days; to children – 0,025 g/kg of body weight of 1 times a day, once;
• Mephitic gangrenes: To 0,5 g there are each 12 hours;
• Amoebic dysentery: to adults and children with the body weight of 35-60 kg – 1,5 g of 1 times a day, with body weight ≥ 60 kg – 2 g a day, to children with body weight ≤ 35 kg – 0,04 g/kg of the body weight (daily dose); a course – 3 days;
• Amebiasis (other forms): adults and children are later 12 years old – 0,5 g, children are 7-12 years old – 0,375 g, children are 1-6 years old – 0,25 g, to children till 1 year – 0,125 g; the daily dose is divided into 2 receptions (in the morning and in the evening), a course – 5-10 days;
• Lambliasis: to adults and children with body weight ≥ 35 kg – 1,5 g of 1 times a day, to children with body weight ≤ 35 kg – 0,04 g/kg a day; a course – 1-2 days;
• Prevention of mephitic gangrenes: before operation – 0,5-1 g once; after operation – 0,5 g 2 times a day, a course – 3-5 days.

Tablets are vaginal
Tablets apply intravaginalno.

The vaginal tablet taken from packaging needs to be entered deeply into a vagina after the corresponding hygienic processing of genitalias.

For therapy of trichomoniasis apply for the night 0,5 g (1 tablet) intravaginalno in a combination with Ornisid's reception orally (tablets to intake) in a dose of 1 g of 1 times a day or on 0,5 g 2 times a day (in the morning and in the evening), a course – 5 days.

Side effects

• Central and peripheral nervous system: dizziness, an incoordination of movements, a headache, spasms, consciousness disturbance, rigidity, a tremor, a peripheral neuropathy touch or mixed;
• Alimentary system: diarrhea, nausea, vomiting.

Overdose symptoms tablets Ornisid for oral administration are: "a depressive triad", epileptiform spasms, peripheral neuritis. Performing symptomatic therapy is recommended, at epileptiform spasms use diazepam.

Special instructions

During passing of a course of therapy by Ornisid it is required to refrain from sexual contacts.

At treatment of the vaginitis caused by a vulval trichomonad (Trichomonas vaginalis), passing of a simultaneous course of therapy which is reasonable to carrying out by tablets Ornisid for intake is recommended to the sexual partner.

Due to the risk of development of a leukopenia at combined use of peroral and intravaginalny forms of drug, especially in case of repeated therapy, it is necessary to control a pattern of peripheral blood.

Medicinal interaction

• Anticoagulants of a coumarinic row – орнидазол their effect strengthens;
• Vekuroniya bromide – is prolonged its myorelaxation action;
• Ethanol – орнидазол does not inhibit an atsetaldegiddegidrogenaza.

Terms and storage conditions

To store in unavailable to children, the dark, dry place at a temperature up to 30 °C.

Period of validity – 2 years.