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Tubulointerstitsialny nephrite

Tubulointerstitsialny nephrite is the disease of kidneys proceeding with preferential defeat of intersticial fabric and renal tubules. In addition in inflammatory process at this disease there are involved also all other structures of tissue of kidneys. Tubulointerstitsialny nephrite can be acute and chronic. Тубулоинтерстициальный нефрит - острое или хроническое заболевание почек

Reasons

The reasons of this disease can be various, but most often connect developing of acute tubulointerstitsialny nephrite using some medicines (antibiotics, non-steroidal anti-inflammatory drugs, diuretics, etc.). Other reasons leading to development of acute tubulointerstitsialny nephrite are some immune diseases, poisonings with heavy metals, ethanol, ethylene glycol.

Chronic tubulointerstitsialny nephrite can be an outcome of an acute form of a disease. But most often arises without the previous acute tubulointerstitsialny nephrite. Are the reasons of its emergence:

Household, production or medicamentous intoxications;
Influence of the ionizing radiation;
Metabolic disturbances;
Infections;
Immune shifts.

Quite often chronic tubulointerstitsialny nephrite arises at the people abusing non-steroidal anti-inflammatory drugs.

Tubulointerstitsialny nephrite: symptoms

At acute tubulointerstitsialny nephrite patients complain of fervescence, pruritic skin rashes, pains in lumbar area, the increased weakness and fatigue. At an acute form of tubulointerstitsialny nephrite symptoms of an acute renal failure very quickly begin to join the symptoms described above also: increase in arterial pressure, nocturia, polyuria or oligoanuriya.

At early stages of a chronic form of tubulointerstitsialny nephrite symptoms most often are absent. They appear only when inflammatory process leads to considerable disturbance of concentration function of kidneys and development of a chronic renal failure.

Tubulointerstitsialny nephrite at children

Диетический стол №7 - составляющая лечения тубулоинтерстициального нефрита Tubulointerstitsialny nephrite at children is rather often met pathology. Most of researchers considers that this disease has an immunoallergic origin since usually arises at the children and teenagers having genetic predisposition to disturbances of functions of the macrophagic englobing system and unresponsiveness changes.

Very often tubulointerstitsialny nephrite at children arises against the background of various dismetabolichesky nefropatiya (in 14% of cases). In addition, developing of this disease at children is promoted by frequent and sometimes uncontrolled treatment by their sulfanamide drugs and beta лактамными antibiotics (ampicillin, penicillin, cefazolin, etc.).

For prevention of emergence at children of tubulointerstitsialny nephrite it is very important not to self-medicate, accept any medicines only on doctor's orders and in the presence to them accurate indications. In addition, it is necessary to reveal timely at children and to treat any infectious, allergic, immune diseases, and also disbolism.

Tubulointerstitsialny nephrite: treatment

Main objective of treatment of tubulointerstitsialny nephrite is identification and elimination of the reason which led to development of a disease. At tubulointerstitsialny nephrite use by short courses of glucocorticoid therapy and/or tsitostatik is possible. Correction of disturbances of water and electrolytic balance is surely carried out. Important value in treatment of tubulointerstitsialny nephrite is allocated also for a dietotherapy (table No. 7). At development of an end-stage of a chronic renal failure carrying out a hemodialysis and transplantation of a kidney is shown.

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