Betadin

Pharmacological action

Betadin is an antiseptic agent for the topical administration, representing a combination of iodine and connecting it polyvinylpirrolidone.

The complex of these substances is called povidone-iodine, also the international unlicensed name of Betadin sounds. This drug renders bactericidal, antiseptic, antiviral, antiprotozoan (influences the elementary), antifungal and disinfecting action. The iodine which is Betadin's part at contact with skin or mucous membranes is released from a complex with polyvinylpirrolidone and damages cells of pathogenic microorganisms. Drug begins to work within 15-30 seconds after use, and for 1 minute there is a full death of microorganisms. Color of iodine which after contact with microbes, mushrooms, protozoa and viruses begins to weaken testifies to Betadin's efficiency.

Prolonged topical administration of Betadin causes considerable absorption of iodine, especially when processing extensive wound surfaces, however after the last use of drug within 1-2 weeks concentration of iodine is returned to blood to an initial indicator. Clinical trials and Betadin responses demonstrate that this drug works longer, than usual spirit solutions of iodine, and also does not render irritant action.

Indications to use

Betadin is issued in the form of an aerosol, a concentrate for preparation of solution, ointment, suppository and solution, each of forms has the indications to use.

Ointment Betadin is appointed in the following cases:

• prevention of infection at small grazes, cuts, burns, small surgical interventions;
• treatment of the infected decubituses or trophic ulcers;
• treatment of the fungal, bacterial and mixed skin infections.

According to the instruction to Betadin, drug in the form of solution is used at:

• to antiseptic processing of burn wounds;
• antiseptic processing of mucous membranes or skin before procedures and operations;
• hygienic or surgical disinfection of hands;
• bladder catheterization, carrying out punctures, injections, capture of a biopsy;
• pollution of mucous membranes or skin the infected material as first aid.

Betadin it is reasonable to use candles at:

• acute and persistent infections of a vagina: bacterial vaginosis, genital herpes, mecotic infection and others;
• as a part of a combination therapy at a trichomoniasis;
• to the processing accompanying diagnostic and obstetric procedures, and also transvaginal surgeries;
• fungal infections of a vagina which were provoked by therapy by antibacterial and steroid medicines.

Application instruction of Betadin

Ointment Betadin is used locally. Before putting drug the wound surface should be cleared and dried up. Ointment Betadin is applied by a thin layer then it is possible to apply an aseptic bandage. Infectious wounds are processed 1-2 times a day within two weeks. For prevention at pollution ointment Betadin is usually used 1 time in three days to those a time, the desirable effect will not be reached yet.

Betadin solution can be applied in not divorced or divorced water look:

• for processing of small grazes, wounds, burns the solution concentrated 10% is used;
• pustulous diseases of skin and acne rash, according to the instruction to Betadin, are wiped with a tampon with the solution concentrated 10% or 5% (1 part of solution and 2 parts of water);
• disinfection of healthy sites of skin before various medical manipulations (blood capture, a puncture, infusion, a biopsy, a transfusion) is made by means of strong solution within 1-2 minutes;
• for disinfection of mucous membranes and skin before operative measures Betadin's solution for two minutes two times is used; rubdown of the patient before operation is carried out by the sponge moistened in 0,1% - 0,05% solution which turns out by dilution of one part of 10% of solution 100 and 200 parts of water respectively;
• effects of invasive manipulations are treated by means of 10% or 5% of solution;
• for aseptic maintaining wounds and treatment of complications use 5% solution or without cultivation;
• treatment of burns can be made 10%, 5% or 1% (1 part of Betadin and 10 parts of water) by solution depending on a condition of a burn surface;
• for washing of a cavity of joints and serous cavities – 1% - 0,1% solution;
• in ophthalmology and transplantology – 1% - 5% solution;
• at surgical treatment of cysts of parenchymatous bodies, when carrying out small gynecologic operations, strong solution of Betadin is applied to processing of patrimonial ways;
• for processing of skin of newborns use 0,1% solution, for an umbilical wound – 10% solution, and for prevention of conjunctivitis at babies – on 2-3 drops in eyes of 2,5% - 5% of solution;
• at bacterial or fungal dermatitis – 1% solution;

• papillomas and herpetic rashes on skin are processed by strong solution of Betadin.

Betadin it is necessary to wet candles before use a little. It is recommended to use before going to bed to 1 suppository which needs to be entered deeply into a vagina. Betadin candles can be used during periods. The course of treatment usually makes 1 week, however in case of incomplete efficiency Betadin of candles a course of use can be prolonged. Also on doctor's orders the single dose can be increased to two suppository. In comments on Betadin there are recommendations concerning use of hygienic laying during treatment by this drug.

Side effects

Comments on Betadin confirm good tolerance of drug, however confirm that the hyperemia, an itch, hypersensitivity reaction are in some cases possible.

Predisposed patients can face the hyperthyroidism (the increased production of hormones of a thyroid gland) caused by iodine. The instruction to Betadin warns about probability of emergence of anaphylactic reactions (suffocation, hypotension), and also dermatitis with development of psoriazopodobny elements.

Betadin's use on extensive sites can provoke increase in level of sodium in blood, disturbance of functions of kidneys, a metabolic acidosis.

Contraindications

According to the instruction, Betadin is not appointed at:

• disturbance of functions or adenoma of a thyroid gland;
• hyperthyroidism;
• herpetiform dermatitis of Dyuringa;
• renal failure;
• hypersensitivity to iodine.

Betadin's use is contraindicated to children till 1 year, to pregnant women and the feeding women, and also before and after introduction of a radioiodine.

Additional information

It is necessary to store drug in the dark, dry and cool place. Ointment storage Betadin is admissible at a temperature which is not exceeding ^250C and it is no more than 75% of humidity.

The period of validity of solution and ointment makes 3 years, Betadin of candles – 2 years.