Application instruction:
Diwine – anticlimacteric drug.
The difault is released in the form of tablets of two types (on 21 pieces in the blister, on 1 or 3 blisters in a cardboard pack with a calendar scale):
Active agent is a part of 1 tablet of white color: oestradiol valerate – 2 mg.
Active agents are a part of 1 tablet of blue color: oestradiol valerate – 2 mg; acetate of a medroksiprogesteron – 10 mg.
Auxiliary components: коллидон 25, monohydrate of lactose, corn starch, magnesium stearate, gelatin, indigo carmine (E132), talc, the purified water.
The difault is appointed to women in a climacteric for stopping of the symptoms arising because of deficit of progesterone and estrogen.
Also drug is shown to women in a postmenopause for prevention of osteoporosis.
The difault should be accepted inside, more preferably in the evening.
Drug for 21 days is accepted on 1 tablet a day. After that within 7 days do a break. During this period there has to come menstrualnopodobny bleeding.
The first 11 days it is necessary to take a pill of white color (with the content of estrogen), then during the next 10 days – the tablets of blue color containing 2 components (estrogen and progesterone).
In cases when the normal menstrual cycle stopped or it became irregular, Divina's reception can be begun at any time. Also therapy can be begun for the fifth day of periods.
At the admission of reception of a dose, it needs to be accepted within the next few 12 hours. Further drug is accepted according to the usual scheme.
During therapy development of disturbances from some systems of an organism is in rare instances possible:
Because in a climacteric duration of a menstrual cycle can be various, bleeding at some women can begin even during reception of blue tablets. In this case it is necessary to stop temporarily Divina's reception, and after the termination of bleeding to resume reception of white tablets.
The difault can reduce efficiency of peroral hypoglycemic drugs, peroral anticoagulants and anti-hypertensive means.
At simultaneous use anticonvulsant drugs, barbiturates, rifampicin and tetracyclines lower Divina's effect.
To store in the place, unavailable to children, at the room temperature (15-25 °C).
Period of validity – 5 years.
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