Phenibutum

Phenibutum - nootropic medicine with anxiolytic activity.

Structure and form of release

Drug is produced in the form of tablets. One tablet contains active agent – Phenibutum of 250 mg.

In packaging on 10, 20 or 50 tablets.

Pharmacological action

According to the instruction Phenibutum is the nootropic drug representing gamma amino - beta fenimaslyanoy acids a hydrochloride.

Use of Phenibutum makes direct impact on GABA receptors, and also renders antiagregantny, tranquilizing, antioxidant and psychogogic action.

Phenibutum influences cerebral circulation, normalizes metabolism of fabrics that improves a functional condition of a brain (increases the linear and volume speed of a blood-groove, reduces a tone of vessels of a brain, makes antiagregantny impact on a brain, improves microcirculation). According to reviews Phenibutum promotes disappearance or the maximum reduction of feeling of alarm, fear and concern, has anticonvulsant effect and favorably influences a dream.

Drug does not exert impact on adreno-and holinoretseptor. Reduces expressiveness and duration of a nystagmus, extends stage of latency. Positively Phenibutum influences psychological indicators (memory, attention, accuracy and speed of sensory-motor reactions). Reduces manifestations of an adynamy, promotes improvement of intellectual working capacity, minimizes vazovegetativny symptoms (a headache, sleep disorders, emotional lability, irritability, heavy feeling in the head).

Course use of Phenibutum promotes improvement of intellectual and physical effeciency, normalizes a dream and improves memory. According to reviews Phenibutum considerably improves a condition of patients with speech and motive disturbances. Patients with an adynamy feel improvement from the first days of administration of drug, the motivation to activity increases. Drug has no exciting or sedative effect.

At such indications to Phenibutum as neurogenic damages of a stomach and heart, it stabilizes processes of a peroksidation of lipids. Does not cause excessive slackness in elderly patients, and the weakening after-effect is absent. In tissues of an eye improves microcirculation, reduces the oppressing impact of ethanol on TsNS.

Indications to use

According to the instruction Phenibutum is shown at:

• alarming and neurotic and asthenic states, fear, neurosis, the increased uneasiness, psychopathy, persuasive states;
• enuresis, tics and stutter at children;
• sleeplessness and nightmares at elderly people;
• to ischuria against the background of myelodisplasias;
• to primary open angle glaucoma (in a combination with other medicines);
• Menyer's disease and dizzinesses caused by dysfunctions of a vestibular mechanism of various etiology (including at traumatic and vascular disorders, an otogenic labyrinthitis);
• treatment of alcoholism, for stopping of somatovegetativny and psychopathological frustration at an abstinence syndrome;
• treatment of delirious and predeliriozny states at alcoholism (as a part of a combination therapy).

The indication to Phenibutum is the uneasiness prevention arising before carrying out surgeries or painful diagnostic testings and also prevention of motion deseases at kinetoza.

Contraindications

Phenibutum is contraindicated at hypersensitivity to the operating component.

With care it is necessary to appoint drug at a liver failure and erosive язвеных gastrointestinal tract diseases.

Route of administration of Phenibutum and mode of dosing

According to the instruction Phenibutum is accepted inside, irrespective of meal. The dosage, frequency rate of reception and duration of therapy depends on portability, age of the patient and indications to Phenibutum.

As a rule, the one-time dosage for children varies within 20-250 mg a day, for adults – 20-750 mg a day.

Side effects of Phenibutum

According to reviews Phenibutum can cause the following by-effects:

• System of digestion: nausea, in particular at the first receptions.
• Central nervous system: excitement, irritability strengthening, drowsiness, headache, dizziness.
• Allergies: itch, skin rash.

Use of Phenibutum during pregnancy and breastfeeding

During pregnancy and a lactation Phenibutum can be applied, but only at a ratio of advantage and risk for mother and the child.

Medicinal interaction of Phenibutum

Phenibutum strengthens action of narcotic analgetics, somnolent, protivoparkinsonichesky, antipsychotic and antiepileptic medicines.

Special instructions

According to reviews Phenibutum influences ability to drive the car and other means demanding the increased concentration of attention.

At the expressed phenomena of a motion desease, such as severe dizziness and pernicious vomiting, drug is ineffective.