Solution for infusions (in ampoules on 5 ml, in a cardboard pack of 10 ampoules; in a blister strip packaging on 5 ampoules, in a cardboard pack 1 or 2 packagings);
Concentrate for preparation of solution for infusions (in ampoules on 5 ml, in a cardboard pack of 10 ampoules; in a blister strip packaging on 10 ampoules, in a cardboard pack 1 or 2 packagings);
Tablets of 250 mg (on 10 pieces in a blister strip packaging, in a cardboard pack on 3 or 6 packagings; on 30 pieces in a blister strip packaging, in a cardboard pack 1 or 2 packagings);
Tablets of 750 mg (on 10 pieces in a blister strip packaging, in a cardboard pack of 3 or 5 packagings).

Active ingredient – arginine a glutamate:

1 ml of solution – 40 mg;
1 ml of a concentrate – 400 mg;
1 tablet – 250 mg, 750 mg.

Indications to use

Poisoning with hepatotropic poisons – chemicals, poison of a death angel, medicines;
Hepatitis of various genesis in an acute or chronic form;
Damage of a liver at a hay fever;
Cirrhosis;
Hepatic encephalopathy;
Condition of heavy and average degree of acute alcoholic poisoning, including alcoholic encephalopathy and coma;
The Postintoksikatsionny pathologies caused by alcohol intake;
Prekoma and a coma, against the background of a giperammoniyemiya.

Besides, use of tablets of 750 mg is shown for prevention of a drunkenness, a hungover syndrome.

Contraindications

Contraindications to Glutargin's use in the form of solution, a concentrate, tablets of 250 mg:

Feverish states;
Acute psychosis;
Heavy functional disturbances of kidneys;
Period of pregnancy and breastfeeding;
Hyperexcitability.

Experience of use of drug in the form of tablets at children is insufficient.

States at which it is forbidden to appoint tablets of 750 mg:

Pregnancy and period of a lactation (breastfeeding);
Age up to 18 years;
Hypersensitivity to drug components.

With care of a tablet of 750 mg apply at a hyperexcitability, heavy disturbances of filtrational function of kidneys, feverish states.

Route of administration and dosage

Solution and concentrate for preparation of solution for infusions: are applied in the way intravenous (in/in) introductions with a speed of 60-70 thaws a minute. Infusion solution prepares in a proportion: 2 g of drug / 150-250 ml of isotonic 0,9% of solution of sodium of chloride. Procedures are carried out by 2 times a day, the maximum daily dose – 8 g;
Tablets of 250 mg: appoint the adult patient orally 3 pieces 3 times a day, irrespective of meal. Course of treatment of 15-20 days. In difficult clinical situations the single dose can be increased to 8 pieces. The maximum daily dose – 32 pieces (8 g);
Tablets of 750 mg: one-time dosing and the period of treatment depend on severity of a disease and 3 times a day within 14-21 days can make from 1 to 3 pieces. Appointment at treatment of alcoholic poisoning – on 1-1,5 pieces 4 times a day every 1-2,5 hour in the first day and on 1 piece 2 times a day in the next 2-3 days. At treatment of heavy degree of alcoholic poisoning, a pill begins to be taken after a course in/in administrations of drug, appoint 1 piece 2 times a day within 20 days. For the purpose of prevention of a drunkenness it is recommended in 1-1,5 hours prior to alcohol intake to take 2,5 pill. Drug is accepted irrespective of meal.

Side effects

At use of tablets side effects in the form of temporary feeling of nausea and slight discomfort in intestines or a stomach right after administration of drug can sometimes be observed.

Special instructions

Patients with pathologies of function of closed glands have to consider ability of drug to slightly increase secretion of a growth hormone and insulin.

Use of tablets of 750 mg does not exert impact on ability to management of vehicles.