Not OVIR
Application instruction:
Not OVIR – an immunostimulator.
Form of release and structure
Is issued in the form of solution for intramuscular introduction: transparent, chartreuse color (on 2 ml in ampoules from dark glass, on 5 ampoules in blister strip packagings, in a pack cardboard 1 packaging).
Composition of solution:
- Active ingredient: oxodihydroacridinylsodium acetate, in 1 ml – 125 mg;
- Excipients: water for injections, citric acid, sodium citrate.
Indications to use
Not OVIR is applied as a part of a combination therapy of the following diseases:
- Radiation immunodeficiency;
- Cytomegaloviral infection at patients with an immunodeficiency;
- Acute and chronic hepatitises B and C;
- Encephalomyelitis and encephalitis of a virus etiology;
- Oncological diseases;
- Venereal lymphogranuloma;
- Epididymites, uretrita, prostatitises, salpingites and tservitsita of a Chlamidia etiology;
- HIV infection;
- Multiple sclerosis;
- The infections caused by a virus of a herpes simplex of type 1 and 2, and also a virus Varitsella-Zoster (including at patients with disturbances of immune system);
- Candidiasis of skin and mucous membranes;
- Flu and other acute respiratory diseases, including at persons with immunodeficiency (treatment and prevention).
Contraindications
- Autoimmune diseases;
- Heavy renal failure (clearance of creatinine less than 30 ml/minute);
- Children's age;
- Pregnancy;
- Lactation;
- Hypersensitivity to drug components.
Extra care during treatment should be observed to patients of advanced age.
Route of administration and dosage
Not OVIR is intended for intramuscular introduction.
The single dose makes 250 mg (1 ampoule) or 4-6 mg/kg of body weight. In need of it increase, but no more than to 500 mg.
If the doctor other is not offered, the course of treatment consists of 5-7 injections with an interval of 48 hours and makes 8-12 days. The general course dose depends on a clinical picture of a disease.
At prolonged and preventive use the drug is administered 1 time in 3-7 days.
At HIV infections Not OVIR is appointed as a part of complex therapy. The course of treatment in this case consists of 10 injections on 250 bucketed mg of 48 hours. The quantity of courses is unlimited on condition of observance of 2-month breaks between courses.
Side effects
- Local reactions: the fast-passing morbidity in an injection site;
- Others: allergic reactions, subfebrile temperature.
Special instructions
At morbidity in an injection site or bad portability of drug Not OVIR is recommended to be entered together with 0,25-0,5% novocaine solution (2 ml).
In case of disturbance of storage conditions of drug opacification of solution till milky-white color is possible. It is impossible to apply it in such look!
Medicinal interaction
Information on physical and chemical incompatibility oxodihydroacridinylsodium acetate with other medicines is absent.
During clinical trials and practice of use of drug any case of incompatibility and potentiation of effects at simultaneous use of Not OVIR with other medicines was not registered.
Terms and storage conditions
To store in the place, unavailable to children, protected from a sunlight and moisture at a temperature of 15-25 ˚С.
Period of validity – 3 years.
Name of drug
Price
Drugstore
Not OVIR solution for инъ 12.5% of amp of 2 ml No. 5, Kardio NPK
1264 rub.
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