Ribomunil
Application instruction:
Ribomunil – medicine of a bacterial origin, a stimulator of nonspecific and specific immunity.
Form of release and structure
Dosage forms:
- Tablets: a round biconvex form, almost white or white color, inodorous (on 12 or 4 pieces in blisters, in a cardboard pack 1 blister);
- Granules for preparation of solution for intake: white color, inodorous (on 1 dose in a bag, in a cardboard pack 4 bags).
The operating Ribomunil's components:
- The bacterial ribosomes titrated to 70% of RNA (including 3,5 shares of ribosomes of Klebsiella pneumoniae, 3 shares of ribosomes of Streptococcus pneumoniae, 3 shares of ribosomes of Streptococcus pyogenes, 0,5 shares of ribosomes of Haemophilus influenzae): in 1 tablet – 0,25 mg or 0,75 mg, in 1 bag – 0,75 mg;
- Proteoglycans of a membrane part (including 15 shares of Klebsiella pneumoniae): in 1 tablet – 0,375 mg or 1,125 mg, in 1 bag – 1,125 mg.
Excipients:
- Tablets: silicon colloid hydrophobic, magnesium stearate, sorbitol;
- Granules: silicon, поливидон, magnesium stearate, D-mannitol, sorbitol.
Indications to use
Ribomunil's use is shown for prevention and/or treatment of recurrent infections of an ear, a nose, a throat and respiratory tracts, including at patients of risk groups:
- Otitis;
- Rhinitis, sinusitis;
- Laryngitis, pharyngitis, quinsy;
- Chronic bronchitis;
- Infectious and dependent bronchial asthma;
- Pneumonia;
- Tracheitis.
Contraindications
- Age up to 6 months;
- Autoimmune pathologies;
- Individual intolerance of components of drug.
Use during pregnancy and breastfeeding is possible if the estimated effect of therapy for mother is higher than potential risk for a fruit or the child.
Route of administration and dosage
Tablets and granules are intended for intake, in the morning, till a breakfast, 1 times a day.
Before reception of a granule it is necessary to dissolve in boiled water of room temperature. It is reasonable to appoint granules to children of early age.
The single dose for patients of all age categories makes 0,75 mg that corresponds to 3 tablets on 0,25 mg, or 1 tablet on 0,75 mg, or 1 bag of granules.
For treatment and/or prevention Ribomunil accept: within three weeks of the first month of therapy – 4 days in a row a week, then 5 months – in the first 4 days of every month.
Side effects
- Allergic reactions: seldom – a small tortoiseshell, a Quincke's disease;
- Others: seldom – diarrhea, nausea, vomiting, at the beginning of use – passing increase in secretion of sialadens (hypersalivation).
Special instructions
Ribomunil's use can cause tranzitorny temperature increase within two-three days therefore patients should be warned about such manifestation of therapeutic effect of drug. Besides, development of passing insignificant symptoms of infections of otorhinolaryngological bodies is possible. Usually these states do not demand the treatment termination.
Treat risk group it is long also often ill patients from 6-month-old till advanced age, including with chronic pathologies of respiratory bodies. Preventive administration of drug is carried out prior to the beginning of an autumn and winter season, especially in regions with adverse ecology.
Purpose of immunomodulator as a part of complex therapy promotes increase in efficiency and reduction of duration of treatment, considerably reduces the need for use of antibiotics, bronchial spasmolytics, prolongs the remission period.
Medicinal interaction
Clinically significant medicinal interaction of Ribomunil it is not established.
Simultaneous use of anti-inflammatory and broncholitic drugs, antibiotics is shown.
Terms and storage conditions
To store at a temperature of 15-25 °C. To protect from children.
Period of validity: tablets on 0,75 mg and granules – 3 years, tablets on 0,25 mg – 5 years.
Statistically, on Mondays the risk of getting injured of a back increases by 25%, and risk of heart attack – for 33%. Be careful.
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