Sedal M

Sedal M – the combined medicine with analgeziruyushchy action.

Pharmacological action Sedal M

The active components which are a part Sedal M have febrifugal and analgeziruyushchy effect, and also eliminate symptoms of flu and ORZ:

• Metamizol sodium has analgesic effect, and also has the expressed spasmolytic effect on smooth muscles of bilious and urinary tract;
• The phenobarbital which is a part Sedal M possesses spasmolytic and sedative action;
• Codeine improves portability of pain and strengthens analgeziruyushchy effect;
• Paracetamol has febrifugal and analgeziruyushchy effect;
• Caffeine, having all-tonic effect, increases arterial pressure at arterial hypotension and physical effeciency, reduces feeling of fatigue and drowsiness, increases heart rate;

Release form

Drug is produced in the form of tablets of white color with a smooth surface. The following active agents are a part Sedal M:

• 300 mg of paracetamol;
• 15 mg of phenobarbital;
• 150 mg metamizole sodium;
• 10 mg of Codeini phosphas;
• 50 mg of caffeine.

The excipients which are a part Sedal M – magnesium stearate, lactose, sodium carboxymethylstarch, starch corn, глицерол, K25 povidone.

On 10 or 20 pieces in packaging.

Analogs Sedal M on active ingredient are drugs Kvintalgin, Pentalginum Nova, Sedalgin-Neo, Pentalgin-ICN and Santoperalgin.

Indications to use Sedal M

According to the instruction Sedal M is applied to stopping moderately or poorly expressed pain syndrome in the following cases:

• Headache;
• Migraine;
• Neuralgia;
• Radiculitis;
• Dentagra;
• Muscle and joints pains;
• Traumatic and postoperative pain;
• Painful periods.

Besides, Sedal M is shown to use at fever and a pain syndrome at acute inflammatory diseases of upper respiratory tracts, flu and other infectious and inflammatory diseases.

Contraindications

It is contraindicated to apply sedal M at:

• The expressed renal failures and liver;
• Bronchospasm;
• Blood diseases, including a leukopenia and hemolitic anemias;
• Craniocereberal injuries;
• Pregnancies and during breastfeeding;
• Arrhythmias;
• Deficit glyukozo-6-fosfatdegidrogenazy;
• Peptic ulcer of a stomach and duodenum, especially in an aggravation phase;
• States which are followed by respiratory depression;
• The increased intracranial pressure;
• Acute myocardial infarction;
• Arterial hypertension;
• Conditions of alcoholic intoxication;
• Hypersensitivity to the Sedal M components.

Also Sedal M according to the instruction is not appointed aged up to 12 years, and at advanced age drug should be taken with caution.

Route of administration Sedal M

Sedal M according to the instruction is accepted to four times a day on 1-2 tablets, but by no more than six in days.

At administration of drug as analgeziruyushchy means duration of a course should not be longer than 5 days. If Sedal M is accepted as an antipyretic, duration of reception makes 3 days.

At overdose Sedal M can lead to oppression of the central nervous system with the following symptoms:

• Dizziness;
• Delay of reflexes;
• Respiratory depression;
• Loss of consciousness;
• Drowsiness;
• Dryness in a mouth;
• Considerable weakness.

For treatment of overdose artificial vomiting, reception of absorbent carbon, a gastric lavage by water and symptomatic therapy is shown.

The concomitant use can lead Sedal M with some drugs to development of undesirable actions:

• At reception with other not opioid analgetics toxic effects can amplify;
• Action Sedal M is weakened by barbiturates and phenylbutazone;
• Toxicity of metamizole sodium is increased by contraceptives and tricyclic antidepressants;
• Tranquilizers and sedatives strengthen analgeziruyushchy action Sedal - M.

Side effects

Sedal M according to the instruction can cause disturbances from some systems and cause the following side effects:

• Drowsiness, dizziness, reduction in the rate of psychomotor reactions;
• Granulocytopenia, leukopenia, agranulocytosis;
• Rash, urticaria, itch;
• Heart consciousness;
• Vomiting, nausea, lock.

At long reception Sedal M in high doses it is possible:

• Easing of analgeziruyushchy effect;
• Abnormal liver function and kidneys;
• Medicinal dependence.

Storage conditions Sedal M

Sedal M according to indications can be bought without recipe. It is not necessary to store tablets more than 36 months (the recommended storage temperature – to 25 °C).