Sumamigren

Sumamigren – the antimigrenozny drug used at treatment of diseases of a nervous system.

Pharmacological action of Sumamigren

Active ingredient of tablets Sumamigren – суматриптан, is a specific selection agonist of vascular 5-gidroksitriptamin-1-receptors which has no influence on other subtypes of 5HT-serotoninovy receptors. Receptors of 5-gidroksitriptamin-1-receptors, thanks to the stimulation and an arrangement in brain blood vessels, lead to narrowing of these vessels.

Release form

According to the instruction Sumamigren release in a look:

• tablets of 50 mg, film coated, biconvex, oblong, light pink and white on break, with dividing risky on one of the parties, on 2 pieces in blisters, in cardboard packs;
• film coated, biconvex, oblong, white tablets of 100 mg, on 2 pieces in blisters in cardboard packs.

One tablet of Sumamigren contains 70 mg or 140 mg of a sumatriptan of succinate, 100 mg or 200 mg of cellulose of microcrystallic, 123,5 mg or 247 mg of lactose of monohydrate, 1,5 mg or 3 mg of croscarmellose sodium, 3 mg or 6 mg of magnesium of stearate, 1,5 mg or 3 mg of talc and 500 mkg or 1 mg of silicon of dioxide colloid.

Sumamigren is a part of a film cover of tablets 3,07 mg or 4,1 mg of a gipromelloza, 1,2 mg or 1,6 mg of a macrogoal 6000, 1,31 mg or 1,8 mg of talc, 900 mkg or 1,2 mg of titanium of dioxide, 980 mkg or 1,3 mg of triethyl citrate and 40 mkg of dye crimson (for tablets of light pink color).

Sumamigren's analogs

Sumamigren's analogs on active ingredient are drugs:

• Amigrenin;
• Imigran;
• Migrepam;
• Sumatriptan;
• Sumatriptan Adifarm;
• Sumatriptan Pfayzer;
• Сумиг;
• Sumitran;
• Trimigren;
• Sumatriptan-Teva;
• Ramimed;
• Sumarin.

On the mechanism of action and belonging to one pharmacological group carry medicines to Sumamigren's analogs:

• Зомиг;
• Zomig Rapimelt;
• Нарамиг;
• Релпакс;
• Frovamigran.

Indications to Sumamigren's use

Tablets Sumamigren are appointed when stopping attacks of migraine with aura or without it.

Sumamigren route of administration

According to the instruction, Sumamigren accept inside, without chewing and plentifully washing down with water. The recommended Sumamigren's dose makes one tablet 50 mg or 100 mg.

Contraindications

According to the instruction Sumamigren's use is contraindicated at hypersensitivity to drug components, basilar, hemiplegic and ophthalmoplegic forms of migraine, a stroke, coronary heart disease, occlusal diseases of peripheral vessels, uncontrollable arterial hypertension and the expressed abnormal liver function or kidneys. Also Sumamigren's use is contraindicated at pregnancy and in the period of a lactation, aged up to 18 years and more than 65 years.

With care Sumamigren appoint at controlled arterial hypertension, epilepsy and hypersensitivity to streptocides.

Side effects of Sumamigren

Sumamigren's use, according to reviews, causes side effects from various systems of an organism, namely:

• Bradycardia, spasm of coronary arteries, lowering of arterial pressure, tachycardia, disturbances of a cordial rhythm, myocardial infarction and development of a syndrome of Reynaud (cardiovascular system);
• Nausea, ischemic colitis, vomiting, dysphagy, sensation of discomfort in a stomach (digestive tract);
• Convulsive attacks, dizziness, diplopia, nystagmus, flashing before eyes, partial passing loss of sight, scotoma and decrease in visual acuity (the central nervous system and sense bodys).

Also Sumamigren, according to reviews, causes minor change of activity of hepatic transaminases, an erythema, rash, an itch, urticaria, pain, inflows, feeling of heat, weakness or pricking, dizziness, feeling of a prelum, fatigue or weight and drowsiness.

Storage conditions

According to the instruction, Sumamigren it is necessary to store in the unavailable to children and protected from light hit dry place, at the room temperature up to 25 °C. The medicine period of storage at observance of recommendations makes 5 years.