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Aponil

Таблетки АпонилAponil – the medicine from the NPVS group having febrifugal, analgeziruyushchy and antiinflammatory effect.

Form of release and structure

Drug is produced in tablets a dosage of 100 mg. The main active ingredient – Nimesulide.

Indications to use

  • Pain syndrome of various etiology (tooth, head, postoperative, posttraumatic pain, альгодисменорея);
  • Fever;
  • Inflammatory diseases of a musculoskeletal system (miositis, arthritis, osteoarthritis, bursitis, tendovaginitis).

Contraindications

  • Ulcer and erosive damages of a GIT in the period of an aggravation;
  • Aspirinovy asthma;
  • Gastrointestinal bleeding;
  • Heavy disturbances of functions of a liver and kidneys;
  • Pregnancy in the III trimester;
  • Lactation period;
  • The age is younger than 12 years;
  • Hypersensitivity to medicine components.

Route of administration and dosage

Aponil accept 2 times a day after food, washing down with water.

For adults the dose of drug makes from 50 to 200 mg at one time, on average – 100 mg.

For children of 12 years drug is appointed at the rate of 1,5 mg/kg of body weight, but by no more than 100 mg.

The most admissible daily dose of medicine makes 400 mg for the adult and 5 mg/kg of body weight for the child.

Side effects

  • From bodies of the alimentary system: pains in a stomach, ulcers on a mucous membrane of a GIT, nausea and vomiting, heartburn, diarrhea;
  • From a nervous system: drowsiness, headache, dizziness;
  • From urinary tract: seldom – hypostases, a delay in a liquid organism, blood in urine, an oliguria (reduction of amount of urine);
  • From the hemopoietic system: anemia, agranulocytosis, leukopenia, thrombocytopenia;
  • Allergic reactions: urticaria, rash; in rare instances – an acute anaphylaxis.

At exceeding of a dose emergence of nausea and vomiting is possible. At overdose carry out a gastric lavage and reception of adsorbents. In case of need apply infusional therapy, appoint osmotic diuretics, carry out a symptomatic treatment.

Special instructions

Aponil it is necessary to appoint with care with the increased arterial pressure, heart failure and a diabetes mellitus of the second type.

At an abnormal liver function and kidneys, at stomach ulcer and a duodenum, a lupus erythematosus, at co-administration with diuretic drugs and anticoagulants it is necessary to accept drug in low doses.

With care medicine is appointed to elderly people.

Analogs

Drugs belong to structural analogs of Aponil: Nayz, Nipulid, Auronim, Flolid, Kokstral, Aktasulid, Nimika, Nimesulide, Prolid, Ameolin, Nimiesang.

Conditions and periods of storage

To store at a temperature not above 25 °C.

Period of validity – 3 years.

 
 
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