Disease Krone

Disease Krone call a chronic inflammatory disease of intestines of which formation of ulcerations on a mucous membrane of a gut is characteristic, on site which granulomas expand afterwards, commissures and strictures are formed that narrows a gleam of a gut and breaks its passability. Most often a disease the Krone affects a small intestine, namely an ileal colon (a terminal ileitis, a regional ileitis, a transmural ileitis), but can arise throughout intestines (granulematozny enteritis, granulematozny colitis, regional enteritis and so forth). Besides, at this disease there are multiple abenteric manifestations.

Disease the Krone at children has favourite localization in duodenal and to a jejunum, often completely strikes a small bowel (jejunoileitis).

Men and women to the same extent, average age of sick from 20 to 30 years are subject to a disease. The disease Krone at children is shown usually at teenage age – 12-12 years.

At the moment the disease is considered incurable, the purpose of treatment of a disease Krone – maintenance of intestines in a condition of long remission and relief of symptoms at an aggravation, and also prevention of complications.

Etiologies Krone

Disease origins Krone are still not clear. Researchers allocated several factors which are important in the mechanism of a chronic inflammation of intestines, however the starting moment in pathological process is not known. Treat the promoting factors:

• Failure in immune system of an organism. In the mechanism of maintenance of an inflammation the autoimmune component, that is pathological reaction of immune system to own body tissues, and also to those microorganisms of intestines which are not pathogenic plays an important role and are necessary for assimilation of food:
• Genetic predisposition. It is known that at people with a disease Krone often relatives have chronic inflammatory diseases of intestines, for example, of ulcer colitis;
• The damaging influence of external factors: unhealthy food, addictions, wrong way of life, infection.

Disease symptoms Krone

The triad of the main symptoms of a disease Krone includes an abdominal pain, chronic diarrhea and weight loss.

The abdominal pain (abdominal pain) is most often shown in the right lower part of ileal area (an ileitis Krone), has the stupid, aching character. Sometimes pain is absent, and in the lower right part of a stomach unpleasant weight and a raspiraniye is felt.

At a disease Krone appetite is often reduced, but even if it is not changed, weight loss, and often very considerable is all the same noted.

Approximately at 30% of patients disease symptoms Krone are disturbances from an anus and a rectum: rectal cracks, puffiness and irritation of an anus that can cause pain at defecation, and also mucifying and blood from an anus.

Disease the Krone at children has some features of a current. Strong loss of weight, loss, sometimes full, appetite, a delay in development is characteristic of children with this disease. The Krone at children is one of disease symptoms the rise in temperature to high figures which is often followed by joint pains.

Abenteric symptoms of a disease Krone can mislead at diagnosis. Treat them: arthritises, arthroses, zhelchekamenny and pochechnokamenny diseases, hepatitises, an inflammation of a mucous membrane of eyes and a mouth, and also skin manifestations – dermatitis, eczemas, rash and long not healing ulcers.

Diagnosis of a disease Krone

Diagnosis of a disease is carried out in the presence of characteristic symptoms of a disease Krone using the next researches:

• Endoscopy. The method consisting in introduction to intestines of the tool consisting of the flexible tube supplied with the video camera and a light source by means of which the mucous membrane of a direct and large intestine is investigated.
• Intestines roentgenoscopy. The techniques using a contrast agent allowing to find new growths, granulomas and sites of narrowing in a small intestine are used;
• Biopsy of a mucous membrane of intestines. Fabric for a histologic research undertakes during a kolonoskopiya. In vitro analyze changes in a mucous membrane;
• Laboratory methods of a research. Carry out the general and biochemical analyses of blood, urine, the analysis and бакпосев a calla, and also the developed blood immunoassay.

Treatment of a disease Krone

As it was already mentioned above, the disease Krone belongs to diseases incurable for today. However treatment of a disease Krone is not just necessary, and has to be consecutive and constant, for maintenance of normal quality of life of the patient. In case of lack of adequate treatment a disease the Krone always has the adverse forecast as leads to development of one or several heavy complications, and is frequent not only from intestines, many of which pose direct threat for life.

Treatment of a disease Krone conservative, at development of complications resort to an operative measure.

Drug treatment of a disease Krone in the period of an aggravation consists in use of anti-diarrheal means, antiinflammatory (hormonal therapy by corticosteroids), the antibacterial drugs and drugs suppressing excessive activity of immune system (immunodepressants).

During remission treatment of a disease the Krone comes down to observance of a diet and maintenance of a healthy lifestyle.

The diet at a disease Krone limits the use of the heavy, rough food rendering irritant action on a mucous membrane of intestines, and also fats and milk. The easily digested and easily acquired food, with the limited use of fermented milk products, sparing for digestive tract is recommended. It is extremely important that a diet at a disease the Krone was balanced as at this disease anemias and avitaminosis because of bad assimilation of food are frequent.

Gastroenterologists recommend individual selection of dishes: in the period of an aggravation rigidly limited diet of the first table, then gradual introduction of separate products and observation of reaction of an organism on them. The products causing an aggravation are excluded from a diet completely. The diet at a disease Krone has to be kept constantly, during all life. It is especially important to conform to these rules at a disease Krone at children, otherwise the disease can hard affect all physical development of the child.

Disease complications Krone

Disease the Krone can cause heavy complications which treat: fistulas, fistulas and diverticulums of intestines, cancer of intestines and biliary tract, intestinal impassability, peritonitis, intestines abscesses, perforation of intestines. The majority of these complications demand the acute surgical management.

Other group of complications are abenteric manifestations which can reach any severity.