Charozetta

Charozetta – contraceptive tablets.

Structure and form of release

Drug is produced in the form of the round, biconvex tablets covered with a white film cover. One tablet contains active component – dezogestret 75 mkg.

Additional components: corn starch, colloid silicon dioxide, stearic acid, monohydrate of lactose, alpha tocopherol, povidone.

In blisters on 28 tablets.

Pharmacological action of Charozetta

Charozetta – an oral gestagensoderzhashchy contraceptive which active agent is dezogestret. Best of all Charozetta's reception is suitable when breastfeeding, and also for women who do not wish to accept estrogen. Or it is contraindicated to them to do it. The effect of contraceptive tablets of Charozett is reached preferential by suppression of an ovulation. Other effects consist in increase in viscosity of cervical slime.

Ovulation frequency at Charozetta's reception in the first 56 days does not exceed 1%. After the termination of 56-day use of drug the ovulation comes for the 7-30th day.

Indications to Charozetta's use

According to the instruction Charozetta is shown as contraceptive means.

Route of administration of Charozetta and mode of dosing

According to the instruction Charozetta is intended for intake. The dosage makes one tablet a day. Charozetta's reception should be carried out every day in identical time for 28 days of a cycle, starting with the first, in the order specified on packaging. Each following packaging should be begun at once after the termination previous, without doing a break.

Use is allowed drug from the 2-5th days of a cycle, however in this case is recommended to use additional barrier methods of contraception for the first seven days of administration of drug.

Contraindications

According to the instruction Charozett is not recommended to apply in the presence at least one of following states:

• the assumed or established hormonedependent tumors;
• the assumed or established pregnancy;
• existence in the anamnesis or at the moment serious illness of a liver;
• existence in the anamnesis or at the moment venous thromboembolism, including thromboembolism of a pulmonary artery, deep vein thrombosis;
• hypersensitivity to a dezogestrel or additional components of drug;
• existence in the anamnesis or at the moment renal failure;
• bleedings from a vagina for the obscure reasons.

In case of manifestation of above-mentioned symptoms at the time of use of drug it is recommended to stop its reception immediately.

According to reviews Charozett should appoint with care at:

• the steady hypertensia developing against the background of reception of tablets, or owing to inefficient anti-hypertensive therapy;
• to hloazma, in particular at women who at pregnancy had a hloazma in the anamnesis (during Charozett's reception women with tendency to a hloazma need to avoid sunshine);
• the long immobilization connected with a disease or an operative measure;
• at thromboembolic disturbances.

Side effects of Charozetta

Most often Charozetta according to reviews causes the following by-effects:

• acne;
• irregular bloody allocations;
• morbidity of mammary glands;
• nausea;
• differences of mood;
• increase in body weight.

Can arise less often:

• decrease in a libido;
• headache;
• intolerance of contact lenses;
• urticaria, skin rash, alopecia;
• dysmenorrhea, amenorrhea;
• oothecoma;
• allocations from mammary glands;
• knotty erythema;
• vaginitis;
• ectopic pregnancy;
• increased fatigue.

At Charozetta's combination to other oral contraceptives serious side effects in the form of arterial and venous thromboses, a hloazma and hormonedependent tumors can be observed.

Any reviews of Charozetta testimonial of emergence of serious symptoms of overdose, did not arrive. Most often the overdose by drug makes vomiting, sick and insignificant vaginal bleeding.

Charozetta's use during pregnancy and breastfeeding

Contraceptive tablets of Charozett are contraindicated during pregnancy. By results of the conducted researches high doses of a gestagen can cause a masculinization of a female fruit.

Drug does not influence quantity and quality of breast milk therefore it is resolved during breastfeeding.

Medicinal interaction

Interaction of drug with other medicines is resulted by probability of development of breakthrough bleeding and decrease in contraceptive efficiency.

At a concomitant use of drug with the medicines inducing microsomal enzymes (hydantoins, barbiturates, топирамат, окскарбазепин, carbamazepine, нелфинавир, рифабутин, ритонавир, rifampicin, Primidonum, фелбамат, and also drugs as a part of which there is a St. John's Wort which is made a hole), the clearance of sex hormones can increase. Therefore the women accepting any of these medicines should apply a barrier method of contraception in addition.

In combination with absorbent carbon absorption of a dezogestrel decreases that leads to decrease in contraceptive efficiency.

Charozetta storage conditions

Drug is stored in the dry place at the room temperature not longer than 36 months.

Special instructions

Before Charozetta's reception it is recommended to undergo medical examination which purpose is the exception of probable pregnancy. If the woman has disturbances in a menstrual cycle, it is recommended to establish their reason at first.

It is necessary to know that use of drug does not protect from HIV infection and from diseases, sexually transmitted.

Efficiency of a dezogestrel decreases against the background of reception of other medicines, gastrointestinal frustration, and also in case of the admission of reception of tablets.