Diffusion toxic craw

Diffusion toxic craw (Greyvs's disease, Bazedova a disease) – the disease which is followed by increase in sizes of a thyroid gland and excess production of hormones therefore there is a disturbance of all types of energy and a metabolism in an organism, and also functions of various bodies and systems.

Origins of a diffusion toxic craw

The reason of development of the Bazedovy disease is precisely unknown. The leading role is assigned to disturbance of immune system.

Most often the disease develops as a result of autoimmune processes in an organism when in addition to normal cells of a healthy organism the immune system synthesizes the specific antibodies injuring healthy cells. So, at Greyvs's disease there is a synthesis of abnormal protein which provokes a thyroid gland to hard work.

The disease is followed by a syndrome of the thyrotoxicosis caused by long and resistant excessive quantity in an organism of hormones of thyroxine and triiodothyronine.

It is possible to meet a diffusion toxic craw at women, approximately by 8 times more often more often than at men. Preferential the disease develops in the middle age (30-50 years), but occurs also at teenagers and young people, during pregnancy and a menopause.

Degrees of a diffusion toxic craw

On weight of a course of a thyrotoxicosis distinguish three degrees of a diffusion toxic craw: easy, average and heavy. And on degree of an enlargement of the thyroid gland the disease is divided into 5 stages:

• 1 stage – a thyroid gland is practically not palpated;
• 2 stage – when swallowing a thyroid gland clearly are visible;
• 3 stage – the craw is swept up by a naked eye;
• 4 stage – sharply expressed craw;
• 5 stage – a craw of very big sizes.

Symptoms of a diffusion toxic craw

At easy degree of a diffusion toxic craw are noted the increased nervous irritability, decrease in working capacity, tachycardia (to 100 beats per minute), decrease in body weight (for 10-15% from initial).

At a moderately severe disease the increased nervous irritability belongs to characteristic symptoms of a diffusion toxic craw significantly, tachycardia makes up to 120 beats per minute, working capacity is practically lost, the person grows thin for 20% and more from initial body weight.

The heavy thyrotoxicosis is characterized by strong weight loss (50% of body weight), severe tachycardia (more than 120 beats per minute), heavy nervous irritability. The ciliary arrhythmia, psychoses, heart failure, thyrocardiac damage of a liver is also characteristic of patients with a heavy thyrotoxicosis.

Besides, symptoms of a diffusion toxic craw are expressed by the following manifestations which are classified as:

• Eye symptoms. At the Bazedovy disease it is often possible to observe uniform expansion of a palpebral fissure that makes an impression of an amazed look (protruding eyes). At severe forms of a disease the inflammation of a cornea, a helcoma which create threat to sight is possible.
• Cardiovascular symptoms. The most common symptom – tachycardia. Pulse rate can fluctuate from 90 to 120 and more beats per minute. Development of cardiovascular insufficiency is characteristic of Greyvs's disease that is followed by the expressed hypostases of extremities, cutaneous dropsies, ascites.
• Dermatological symptoms. At the Bazedovy disease the increased perspiration, an erythema, destruction of nails, hypostases standing is observed.
• Symptoms from the alimentary system. Essential increase in appetite is noted. It is connected with acceleration of a metabolism. Because of increase in motility of intestines patients quite often have a diarrhea. Disturbance of work of a liver is observed, up to development of cirrhosis.
• Endocrine symptoms. Depression of function of bark of adrenal glands and gonads is observed, the diabetes mellitus can develop. At women of childbearing age reduction of frequency and quantity of periods is observed.
• Neurologic symptoms. The most common symptoms of a diffusion toxic craw are the increased fussiness, reactivity, excitability, the general motive concern. Trembling of fingers, muscular weakness, a headache is characteristic of patients.
• Dental symptoms. Often the disease is followed by multiple caries, sometimes periodontosis.

Complications of a diffusion toxic craw

The heaviest complication of a disease is thyrocardiac crisis. Its emergence is promoted by the following factors:

• lack of adequate treatment of the Bazedovy disease throughout a long span;
• the strengthened exercise stress;
• the difficult situation which caused a severe stress or a mental injury;
• any operative measures;
• treatment of a craw by means of a radioiodine, and also surgical treatment of a craw without preliminary medicamentous compensation;
• infectious diseases.

At thyrocardiac crisis the excessive amount of thyroid hormones comes to blood that causes extremely severe defeats of cardiovascular and nervous systems, a liver and adrenal glands.

Diagnosis of a diffusion toxic craw

To define a disease does not present special difficulty. Confirm the diagnosis by means of laboratory blood analyses on the level of content of thyroid hormones. Also in blood the increased concentration of iodine and reduced amount of cholesterol is observed.

If in the presence of thyrotoxicosis symptoms the thyroid gland is not probed, its atypical arrangement is probable. However it is necessary to know that symptoms of a thyrotoxicosis can be shown also at other diseases: the mixed and nodal craw, a thyroiditis, cancer and a tumor of a thyroid gland.

Treatment of a diffusion toxic craw

For performing effective therapy it is extremely important to provide to the patient quiet conditions and to adjust a healthy sleep. Food has to be full, with the increased content of vitamins and proteins. Treatment of a diffusion toxic craw can be medicamentous or using a radioiodine. At severe forms of a disease the surgical method of treatment is preferable.

Drug treatment of a diffusion toxic craw, as a rule, quite long. The doctor appoints anti-thyroid drugs, the potassium drugs derivative of thiouracil and an imidazole, iodine drugs, demulcents. The minimum duration of therapy makes half a year. Generally the patient accepts medicines for 1 - 1,5. If medicamentous therapy does not yield positive takes, it is necessary to consider other methods of treatment.

Radioyodoterapiya – quite effective method of treatment which has, however, a set of contraindications which the peptic ulcer, tuberculosis, mental disorders, pregnancy and the period of feeding by a breast are among.

Surgical treatment of a diffusion toxic craw is preferable in the presence of allergic reactions, too big increase in a craw (the 3rd degree above), and also at too expressed symptoms of cardiovascular insufficiency.