Fareston is issued in the form of round flat tablets (20 or 60 mg). One tablet of a medicine contains 20 (60) mg of a toremifen of citrate. Additional components: lactose, cellulose microcrystallic, krakhmalglikolit sodium, starch corn, povidone, magnesium stearate, silicon dioxide colloid anhydrous.

Pharmacological action of Fareston

Fareston possesses anti-oestrogenic and antineoplastic action. The main active ingredient of drug blocks estrogen synthesis, makes combined effect on oncogenous regulation, thereby suppressing reproduction of tumor cells and causing their death. Reviews of Farestona confirm that thanks to drug in treatment it is possible to liquidate a painful nagrubaniye of mammary glands, to liquidate or to considerably reduce the existing fibrous and/or cystous educations, and also to prevent formation of new pathologies. At administration of drug progesterone level in a blood plasma increases, and prolactin level gradually decreases that renders a favorable effect at therapy.

Some reviews of Farestona confirm possible efficiency of drug at treatment of locally-spread and metastatic cancer of kidney.

Indications to Fareston's use

According to the instruction Fareston apply in treatment of the following diseases:

gormonzavisimy metastatic breast cancer (in the post-menopausal period);
dishormonal hyperplasia of a mammary gland.

Contraindications

Contraindications to Fareston's use according to the instruction following:

endometria hyperplasia;
thromboembolism;
pregnancy and period of a lactation;
hypersensitivity to drug;
heavy liver failure.

According to the instruction Fareston is appointed with care at metastasises in a bone tissue, thrombocytopenia, a leukopenia and a hypercalcemia.

Fareston – the instruction to use

It is daily recommended to accept 60 mg of drug as a standard dose for the first line of hormonal treatment. At use of medicine for treatment of the second line of hormonal therapy the daily dose of medicine can be increased to 240 mg. At a renal failure the recommended dose does not need correction.

Side effect of Fareston

Judging by reviews of Farestona, drug is in most cases transferred well, however in some cases can cause the following side reactions: vaginal allocations or bleedings, dizziness, an itch in genitals, increased fatigue, a depression, inflows, the increased perspiration, nausea, sleeplessness.

Фарестон в таблетках The following side reactions are less often observed: short wind, headache, vision disorder (cataract, opacification of a cornea), hearing disorder, vein thrombosis, change of level of enzymes of a liver, embolism of a pulmonary artery. Seldom or never jaundice develops.

At drug overdose (reception more than 680 mg of drug a day) vomiting, faints, a headache, nausea was observed.

Special instructions

Before therapy all patients shall undergo gynecologic inspection. First of all it is necessary to undergo inspection of a mucous membrane of an endometria as risk of development of a hyperplasia, the polypose and endometrial cancer increases in connection with an oestrogenic promoting effect of Fareston.

Patients with cardiovascular diseases, and also with metastasises in a bone need more careful observation.

Interactions

According to the instruction Fareston is not applied with the following medicines:

with neuroleptics (fenotiaziny, Pimozidum, sertindoly, haloperidol, Sulpiridum);
with some antibacterial drugs (moksifloksatsiny, erythromycin, pentamidine, antimalarial means, especially galofantriny);
with some antihistamines (terfenadiny, astemizoly, mizolastiny);
with antiarrhytmic drugs of a class III (Amiodaronum, sotaloly, dofetilidy, ibutilidy);
with antiarrhytmic drugs of the class IA (kvinidiny, gidrokvinidiny, Disopyramidum);
with other drugs (tsizapridy, Vincaminum, bepridily, difemanily).

Simultaneous use of Fareston and thiazide diuretics promotes development of a hypercalcemia. The concomitant use of Fareston and varfarinopodobny anticoagulants can promote increase in duration of bleeding.

Fareston storage conditions

Drug should be stored at a temperature from 15 to 25 °C.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Fareston of a tablet 20 of mg of 30 pieces

1624 rub.

To buy

Apteka вер.ру, LLC

Fareston of a tablet 60 of mg of 60 pieces

4900 rub.

To buy

Apteka вер.ру, LLC

To look at all offers from drugstores

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