Gepatrombin

Pharmacological action

Gepatrombin is the combined drug for external use possessing antitrombotichesky, regenerating, anticoagulating (slows down a blood coagulation), antiedematous and antiinflammatory properties.

Are Gepatrombin's part heparin sodium, дексапантенол and cordianine.

Heparin is anticoagulant of direct action that is explained by its oppressing impact directly on coagulation factors. This substance is extracted from lungs of cattle. Heparin inhibits reactions which cause blood coagulation and formation of blood clots, improves blood supply, promotes washing away of a congestive intercellular lymph and the harmful products formed as a result of substance exchange.

Two other components of Gepatrombin strengthen effect of heparin, improve its penetration, and also protect skin.

Gepatrombin represents antihemorrhoidal means.

Are a part of this drug heparin, Prednisolonum acetate and полидоканол.

Heparin causes antitrombotichesky, antiinflammatory and antiexudative (removes the liquid formed in the place of an inflammation) Gepatrombin G. action.

Heparin prevents blood coagulation in hemorrhoidal nodes, participates in regeneration of connecting fabric. Prednisolonum which is contained in Gepatrombin strengthens effect of heparin, and also reduces inflammatory process, feeling of pain, burning and an itch in anorectal area. Thanks to a polidoknol Gepatrombin promotes a sklerozirovaniye of hemorrhoidal nodes (pasting of walls of a node with the subsequent its drying) and has mestnoanesteziruyushchy effect.

Indications to use

Gepatrombin the instruction recommends drug use at:

• to fibrinferment (formation of clots in a gleam of vessels);
• thrombophlebitis (thrombosis with formation of the blood clot closing a vein gleam);
• varicosity;
• trophic ulcers of a shin;
• tendovaginitis (inflammation of connective tissue covers of a sinew);
• inflammatory infiltrates (accumulation of cellular elements with impurity of a lymph and blood in body tissues);
• to limfagnita (inflammation of lymph nodes);
• mastitis (inflammation of a mammary gland);
• furuncle (an acute inflammation of a hair sack and surrounding its fabrics)
• anthrax (it is purulent - a necrotic inflammation around group of hair sacks).

As clinical trials and responses testify, Gepatrombin is effective also at sports injuries.

Gepatrombin is appointed at outside and internal hemorrhoids; eczema, fistulas (channels with the emitted liquid) and an itch in the field of an anus; thrombophlebitises of veins of an anus; anus cracks.

Application instruction of Gepatrombin

Gepatrombin is issued in the form of gel and ointment which are intended for external use.

Ointment Gepatrombin is applied in the form of a column (about 5 cm) from 1 to 3 times a day directly on affected areas. At diseases of veins ointment Gepatrombin is applied by means of a bandage. Treatment of trophic ulcers provides putting ointment in the form of a ring with a diameter about 4 centimeters. At treatment of veins of the lower extremities drug should be rubbed in the direction from below up the easy movements, at the same time the instruction to Gepatrombin recommends a single dose to put in the separate portions. At treatment of furuncles and anthrax, according to comments on Gepatrombin, the bigger effect gives use of gauze compresses with ointment, than usual putting drug.

Unlike ointment, Gepatrombin in the form of gel it is necessary to apply only on the unimpaired sites of skin.

Gel is recommended to be used several times a day, rubbing from below up the massing movements. Drug in the form of gel, just as ointment Gepatrombin, at thromboses and thrombophlebitises it is necessary to apply without rubbing in and massaging.

Gepatrombin can be applied in the form of ointment or rectal suppository. It is necessary to apply ointment a thin layer 2-4 times a day on affected areas. After painful feelings disappear, drug is used within a week once a day. Candles Gepatrombin are entered into proctal pass after defecation 1-2 times a day. For administration of ointment it is necessary to use the enclosed tip which facilitates drug use process.

Gepatrombin is longer not recommended to apply ointment and candles than two weeks as long use of this drug can provoke development of system side reactions.

Side effects

Comments on Gepatrombin confirm its good tolerance, however allergic reactions (urticaria, skin rash, a Quincke's disease) to drug use are in some cases possible.

Gepatrombin can also be an origin of a dermahemia or allergic reactions.

Contraindications

Before use of ointment or gel of Gepatrombin the instruction has to be attentively studied as in some cases this drug is contraindicated:

• hypersensitivity to active ingredients of drug;
• disturbance of integrity of skin (when using gel);
• the infected damages of skin;
• thrombocytopenia (reduction of concentration of thrombocytes in blood);
• the raised bleeding (hemorrhagic diathesis);
• hemophilia (the hereditary disease which is characterized by the raised bleeding).

Gepatrombin's use by pregnant women and the feeding women perhaps only according to strict indications after consultation of the doctor.

Ointment and candles Gepatrombin cannot be used at:

• hypersensitivity;
• virus, bacterial or fungal infections of skin;
• tuberculosis;
• syphilis;
• skin tumors;
• predispositions to bleedings;
• reactions to introduction of vaccines;
• pregnancies (I trimester).

Additional information

According to the instruction, Gepatrombin and Gepatrombin it is necessary to store at a temperature corresponding ^15-250C. A period of validity of drugs – 3 years.