Элефлокс

Элефлокс – drug of group of ftorkhinolon, antimicrobic means.

Pharmacological action of Elefloks

The main operating component of list of Elefloks is levofloxacin which promotes blocking DNK-girazy and topoisomerases IV of bacteria, suppressing synthesis of DNA and causing morphological changes in their cytoplasm, membranes and a cell wall. Thanks to it bactericidal and antimicrobic impact on the patient's organism is carried out.

Release form

Drug of Elefloks is produced in two forms:

• tablets weighing 250 and 500 mg. Tablets are biconvex, have flesh-colored color, an oval form, are covered with a film cover. On one of the parties an engraving "250" or "500" depending on the mass of active agent. Tablets are packed into blisters on 5 pieces. One pack contains 1 or 2 blisters;
• transparent solution for infusions, possesses in chartreuse color. The bottle contains 100 ml of medicine.

Indications to Elefloks's use

The instruction to Elefloks orders use of drug at the infectious and inflammatory diseases caused by microorganisms, sensitive to effect of drug. Treat those:

• exacerbation of chronic bronchitis;
• diseases of ENT organs;
• acute sinusitis;
• community-acquired pneumonia;
• the complicated and uncomplicated infections of urinary tract (including pyelonephritis);
• infections of soft tissues and skin (abscess, the suppurated atheromas, furunculosis);
• bacterial prostatitis;
• bacteremia, septicaemia;
• intraabdominal infection;
• drug resistant form of tuberculosis (as an element of complex therapy).

Elefloks's contraindications

Medical reviews of Elefloksa allowed to reveal a number of contraindications. Medicine is not recommended to use if the patient gets to one of described below categories:

• epilepsy;
• hypersensitivity to a levofloksatsin or other types of hinolon;
• the damage of sinews caused by earlier carried out therapy on the basis of hinolon;
• age up to 18 years;
• period of pregnancy and lactation.

Drug is allowed to use to elderly people, patients with deficit glyukozo-6-fosfatdegidrogenazy, and also to patients with an impaired renal function only in cases when medical observation can be guaranteed to them.

Application instruction of Elefloks

It is recommended to accept Elefloks before food or in breaks between acceptances of food. Not to chew, wash down plentifully with water. The instruction recommends the following dosages depending on a disease for Elefloks:

• at sinusitis to take 500 mg medicine inside once within a day; at an aggravation of a chronic form of bronchitis – also once a day on 250-500 mg;
• at pneumonia it is necessary to take a pill of Elefloks one or two times a day on 250-500 mg; at in introduction the recommended dose is formed 500 mg 1 or 2 times a day;
• at infectious damages of urinary tract a dosage for in/in and peroral introduction same: once on 250 mg a day;
• at infections of soft tissues and integuments of Elefloks accept inside one or two times a day in number of 250-500 mg.

Side effects

Drug is capable to cause a number of by-effects, however probability of their emergence, judging by reviews of Elefloksa, is small. The following belongs to possible side reactions:

• vomiting, diarrhea, nausea, abdominal pain, loss of appetite, dysbacteriosis, pseudomembranous coloenteritis, hyperbilirubinemia;
• tachycardia, vascular collapse, decrease in the ABP;
• dizziness, weakness, headache, sleeplessness, paresthesias, fear, uneasiness, confusion of consciousness, depression, spasms;
• disturbances of sense of smell, hearing, sight, tactile and flavoring sensitivity;
• myasthenia, arthralgia, rupture of sinews, mialgiya, tendinitis;
• intersticial nephrite, giperkreatininemiya;
• hemolitic anemia, leukopenia, eozonofiliya, agranulocytosis, neutropenia, thrombocytopenia, hemorrhages, pancytopenia;
• allergy in the form of an itch, a photosensitization, hypostasis of mucous membranes and skin, a small tortoiseshell, an exudative erythema, suffocation, an acute anaphylaxis, a vasculitis, an allergic pneumonitis;
• рабдомиолиз, aggravation of a porphyria, superinfection, persistent fever.

Overdose

Elefloks's use and medicine analogs in the doses exceeding recommended is capable to cause emergence of overdose which symptoms are as follows: confusion of consciousness, attacks of spasms as epileptic, dizzinesses, nausea, erosive defeats mucous a GIT.

Treatment is recommended symptomatic since the specific antidote is absent.

Drug analogs

There is a number of the drugs similar on structure and an image of action to Elefloks, their list is given below:

• Glevo;
• Lebel;
• Ivatsin;
• Левофлекс;
• Levofloxacin;
• Леобэг;
• Maklevo, etc.

Storage conditions

Элефлокс it is stored up to 2 years at a temperature which is not exceeding a mark of 25 °C. It is recommended to protect drug from access for children.