Application instruction:
Left thyroxine – the hormonal drug used for diagnosis, treatment and prevention of diseases of a thyroid gland.
Left thyroxine is produced in the form of tablets: ploskotsilindrichesky, white or white with a creamy shade of color (on 10 or 25 pieces in blister strip packagings, on 1, 2 or 5 packagings in a cardboard pack).
Is a part of 1 tablet:
Also Levotiroksin apply as diagnostic means at test of thyroid suppression.
Left thyroxine should be taken with caution in the presence of cardiovascular diseases: coronary heart disease (atherosclerosis, stenocardia, a myocardial infarction in the anamnesis), arrhythmias, arterial hypertension. It is also necessary to be careful at Levotiroksin's use by the patient with a diabetes mellitus, it is long the existing hypothyroidism with a heavy current, a sprue (dose adjustment can be required).
Therapy concerning a hypothyroidism during pregnancy has to continue. Simultaneous use from tireostatika is contraindicated. The feeding women need to take drug with caution under observation of the doctor, with strict observance of the appointed doses.
Left thyroxine is accepted inside, in the morning on an empty stomach (in 30 minutes prior to food), washing down with a small amount of liquid (1/2 glasses of water). It is not necessary to chew a tablet.
The daily dose of drug is defined individually on the basis of indications.
During performing replaceable treatment of a hypothyroidism to patients up to 55 years without cardiovascular diseases Levotiroksin appoint 1,6-1,8 mkg/kg of body weight in a daily dose; the patient of 55 years or in the presence of disturbances of cardiovascular system – 0,9 mkg/kg of body weight. Calculations of a dose at considerable obesity need to be made on "the ideal weight".
At the initial stage of performing replacement therapy at a hypothyroidism by the patient 55 years without cardiovascular diseases drug are younger appoint in the following daily doses:
In the presence of cardiovascular diseases or the patient aged from 55 years Levotiroksin appoint in an initial dose 25 mkg a day. To normalization of level of thyritropic hormone to blood of 1 times in 2 months carry out increase in a dose by 25 mkg. In case of development or deterioration in cardial symptoms it is necessary to carry out correction of cardial treatment.
At treatment of an inborn hypothyroidism Levotiroksin appoint depending on age (a daily dose / dose per body weight):
At other indications appoint the following mode of dosing:
Before test of thyroid suppression Levotiroksin appoint 75 mkg a day in 4 and 3 weeks prior to test, in 2 and 1 week – on 150-200 mkg a day.
Daily dose of Levotiroksin babies are given in 30 minutes before the first feeding in one step. The tablet should be dissolved in water to a condition of a thin suspension (prepare just before reception).
At patients with a severe form it is long the existing hypothyroidism therapy it is necessary to begin with extra care with small doses (12,5 mkg a day). Increase in a dose up to supporting is carried out through more long intervals of time – each 2 weeks on 12,5 mkg a day. Such patients need to determine more often the level of thyritropic hormone in blood.
Left thyroxine at a hypothyroidism is accepted, as a rule, throughout all life. At a thyrotoxicosis drug should be used along with tireostatika after achievement of an euthyroid state.
In all cases duration of therapy is defined by the doctor.
At the correct use of Levotiroksin side effects, as a rule, do not develop.
In case of existence of hypersensitivity to components of drug there can be allergic reactions.
At the hypothyroidism caused by damage of a hypophysis it is necessary to find out whether insufficiency of bark of adrenal glands accompanies a disease. In this case, to avoid development of acute adrenal insufficiency, replacement therapy by glucocorticosteroids needs to be begun prior to therapy of a hypothyroidism with thyroid hormones.
At simultaneous use of Levotiroksin with some medicines there can be following effects:
To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.
Period of validity – 2 years.
The stomach of the person not bad copes with foreign objects and without medical intervention. It is known that the gastric juice is capable to dissolve even coins.
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