The Kapsulovidny tablets covered with a light yellow cover. One tablet contains active agent – thioctic acid of 600 mg. Auxiliary components: talc, microcrystallic cellulose, colloid silicon dioxide, macrogoal 6000, симетикон, sodium lauryl sulfate, magnesium stearate, lactose, monohydrate of lactose, gipromelloz, sodium carboxymethylcellulose. In blisters on 10 tablets.
Light yellow transparent solution for infusions. 1 ml contains active agent – thioctic acid of 12 mg. Auxiliary components: a macrogoal 300, Megluminum, water for injections. In bottles on 50 ml.
Yellowish-green transparent concentrate for preparation of solution for infusions. 1 ml contains active agent – thioctic acid of 30 mg. Auxiliary components: Megluminum, water for injections, a macrogoal 300. In ampoules on 20 ml.

Tiogamma's analogs are the following medicines: Alpha lipoic acid, Berliton, Lipamidum, Lipoic acid, Lipotiokson, Neyrolipon, Oktolipen, Tioctacidum, Tiolepta Tiolipon, Espa-lipon.

Pharmacological action of Tiogamma

According to the instruction Thioscale is metabolic drug. Alpha and lipoic (thioctic) acid is the endogenous antioxidant connecting free radicals. Acid in an organism are synthesized by means of oxidizing decarboxylation of alpha ketonic acids.

Tiogamma's use reduces glucose level in blood, and in a liver increases the maintenance of a glycogen, promotes overcoming insulin resistance.

According to reviews Thioscale in the nature of biochemical influence is similar to group B vitamins. Thioctic acid stimulates cholesterol exchange, regulates carbohydrate and lipidic metabolism, normalizes function of a liver. Drug renders hypoglycemic, hypolipidemic, hepatoprotective and gipokholesterinemichesky action.

Indications to Tiogamma's use

According to the instruction Thioscale is shown at a diabetic polyneuropathy.

Contraindications

In the instruction to Tiogamma the following contraindications are specified:

hypersensitivity;
children's age as safety and efficiency of use are not established;
period of pregnancy and breastfeeding.

During administration of drug or Tiogamma's analog it is necessary to refrain from the use of alcoholic beverages.

Route of administration of Tiogamma and mode of dosing

According to the instruction Thioscale a pill is taken inside, Тиогамма в капсулах without chewing, washing down with a large amount of water. As a rule, inside appoint 300-600 mg a day.

Also administer the drug intravenously in a dosage of 600 mg a day.

At the beginning of therapy it is recommended to enter drug or Tiogamma's analog intravenously for two-four weeks. Later it is possible to pass to tablets in a dosage 300-600 mg a day.

Side effects

According to reviews Thioscale at intake can cause the following by-effects:

system reactions (up to development of an acute anaphylaxis), a small tortoiseshell;
hypoglycemia;
dyspepsia.

According to reviews Thioscale at intravenous administration can cause:

spasms and diplopia;
breath difficulty;
thrombocytopenia, dot hemorrhages in skin, mucous membranes, thrombophlebitis, a purpura.

Overdose

The overdose by Tiogamma according to reviews causes the following symptoms: headache, vomiting, nausea. In this case it is necessary to carry out symptomatic therapy.

Medicinal interaction

At simultaneous use of Tiogamma for intravenous infusions reduces action of Cisplatinum.

In a combination with ethanol efficiency of drug or Tiogamma's analog decreases.

Tiogamma's use during pregnancy and a lactation

According to the instruction Thioscale is contraindicated during pregnancy and breastfeeding.

Tiogamma storage conditions

Drug is stored in the dry place at the room temperature.

The tablets Thioscale should be stored not longer than three years. The concentrate and solution for preparation of infusions can be stored not longer than five years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Thioscale solution for инф. 1,2% 50 ml фл n1 (p)

172 rub.

To buy