Application instruction:
Zirtek – a blocker histamine H1 receptors, antiallergic drug with antipruritic and anti-exudative action.
Active ingredient – a tsetirizina dihydrochloride:
Excipients of tablets: silicon dioxide colloid, lactoses monohydrate, magnesium stearate, cellulose microcrystallic, Opadray of Y-1-7000 (titanium dioxide (E171), gipromelloz (E464), macrogoal 400).
Excipients of drops: the methylparabenevils, пропилпарабензол, propylene glycol, sodium acetate, глицерол, glacial acetic acid, sodium saccharinate, the water purified.
Absolute:
Relative:
Zirtek accept inside.
The recommended doses:
In certain cases to adults and children 6 years for achievement of therapeutic effect enough 5 mg a day are more senior.
To people of advanced age and patients with a renal failure the dose is adjusted depending on the clearance of creatinine (CC) which is calculated as follows:
The recommended Zirtek's doses for patients with a liver and renal failure:
At an end-stage of a renal failure drug is contraindicated.
Dose adjustment is not required to patients for whom only abnormal liver functions are diagnosed.
Zirtek, as a rule, is well had, in rare instances there are following side effects:
At Zirtek's reception in the recommended dose the negative impact on the speed of reactions and ability to concentration of attention was not revealed. Nevertheless, during treatment it is recommended to refrain from driving of vehicles and performance of potentially dangerous types of activity.
Undesirable medicinal interaction of a tsetirizin with glipizidy, erythromycin, ketokonazoly, azithromycin, diazepam, Cimetidinum, pseudoephedrine is not revealed.
At simultaneous use of theophylline (in a daily dose of 400 mg) the general clearance of a tsetirizin decreases by 16%, the theophylline kinetics at the same time does not change.
Data on Zirtek's interaction with alcohol are not obtained, however patients are recommended to refrain from the use of alcoholic beverages during treatment by drug to avoid oppression of activity of the central nervous system.
To store in the place, unavailable to children, at a temperature: tablets – to 30 ºС, drops – to 25 ºС.
Period of validity – 5 years.
Name of drug
Price
Drugstore
Zirtek тбл п / about 10 mg No. 7 *, UCB Farchim
211 rub.
Zirtek of a drop of 1% фл 10 ml, UCB Farchim
319 rub.
In the aspiration to pull out the patient, doctors often go too far. So, for example, a certain Charles Janszen during the period from 1954 to 1994 endured more than 900 operations on removal of new growths.
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