The prices in Internet drugstores:
from 4406 rub.
Amdoal – drug with antipsychotic, antipsychotic action.
Amdoal release in the form of tablets: almost white or white color, round, biconvex, on one party an engraving (depending on a dosage of 10/15/20/30 mg) "N74", "N75", "N76" or "N77" (on 15 pieces in blister strip packagings, on 1-2 packagings in a cardboard pack).
Structure of 1 tablet:
Relative (Amdoal appoint with care in the presence of the following diseases / states):
Amdoal accept inside. Does not accord meal on efficiency of drug of influence.
Frequency rate of reception – once a day.
The recommended mode of dosing (daily dose):
The patient with a renal/liver failure, and also to patients of advanced age the mode of dosing is not adjusted.
At a renal failure in heavy degree it is necessary to appoint a daily dose of 30 mg with care.
When carrying out a combination therapy it is necessary to consider:
At purpose of several medicines inhibiting isoenzymes of CYP2D6 and CYP3A4 it is necessary to consider the possibility of reduction of a daily dose of Amdoal.
Nausea and akathisia belong to number of the most often registered side effects (at more than 3% of patients).
Other possible disturbances (> 10% – are very frequent;> 1% and <10% – is frequent;> 0,1% and <1% – infrequently;> 0,01% and <0,1% – are rare; <0,01% – are very rare):
At treatment of schizophrenia, maniacal episodes and bipolar disorder of the I type by Amdoal the frequency of emergence of extrapyramidal symptoms (EPS) is less, than at the patients receiving a haloperidol, and same, as at the patients receiving olanzapine. Frequency of development of EPS in the patients receiving арипипразол at therapy of bipolar disorder of the I type and maniacal episodes is higher in comparison with group of treatment with use of drugs of lithium.
By results of carrying out post-marketing observations the following side reactions were recorded (with an unspecified frequency of development):
Improvement of a state at Amdoal's use can demand several days in this connection patients have to be under fixed observation.
Tendency, characteristic of psychoses, to suicide attempts / thoughts can arise in short terms after the beginning of therapy or change of drug. The condition of such patients demands careful observation.
In the presence of disturbances from cardiovascular system performing therapy demands care. Because of probability of development of vein thromboses, at the contributing factors to developing of a thrombembolia of veins before Amdoal's appointment it is necessary to conduct careful examination of patients, and also to carry out preventive measures during therapy. In the presence of instructions in the family anamnesis on lengthening of an interval of QT it is necessary to be careful.
The probability of developing of late dyskinesia increases with the drug use duration therefore at emergence during therapy of symptoms of late dyskinesia it is necessary to lower a dose or to cancel treatment. After Amdoal's cancellation these symptoms can is passing to amplify or even for the first time to appear.
At treatment by Amdoal the life-threatening malignant antipsychotic syndrome can develop (the main symptoms: disturbances of mentality, muscular rigidity, a hyper pyrexia, instability of the autonomic nervous system, including instability of arterial pressure / pulse, arrhythmia, perspiration, tachycardia). At emergence of signs of a malignant antipsychotic syndrome or inexplicable fever therapy is cancelled.
At Amdoal's appointment patients in the anamnesis or in the presence of frustration at which they can develop need to be careful with convulsive attacks.
It is not necessary to use drug at treatment of neurosis tardas as at the same time the risk of development of cerebrovascular complications and mortality increases.
Patients with a diabetes mellitus during therapy need to define regularly concentration of glucose in blood. With risk factors of development of a diabetes mellitus (the diabetes mellitus in the family anamnesis, obesity) should be defined concentration of glucose in blood at the beginning of a course, and also periodically in the course of Amdoal's reception. During treatment it is necessary to control constantly hyperglycemia symptoms, including weakness, the speeded-up urination, the increased thirst, a polyphagia.
Administration of drug can lead to aspiration and disturbance of motility of a gullet. With risk of development of aspiration pneumonia Amdoal appoint with care.
During therapy it is necessary to be careful when working, demanding from sick bystry psychomotor reactions and high concentration of attention.
At the combined use of Amdoal with some medicinal means / substances the following effects can be observed:
To store in protected from light, the place, dry, unavailable to children, at a temperature up to 30 °C.
Period of validity – 3 years.
Name of drug
Amdoal of 10 mg of n30 таб.
Amdoal of a tablet 15 of mg of 30 pieces
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