Avekort

Avekort – outside drug with antiinflammatory and antiallergic action.

Form of release and structure

Avekort produce in the form of ointment for external use 0,1%: from color, white to white with a yellowish shade, has a slight specific smell (in aluminum tubas on 15 or 30 g, on 1 tuba in a cardboard pack).

Is a part of 100 mg of ointment:

• Active agent: furoate of a mometazon – 0,1 mg;
• Auxiliary components: propylene glycol – 12 mg, glyceryl monostearate – 2 mg, emulsion wax – 5 mg, vaseline – 77,9 mg, phosphoric acid – to рН 3,0-7,5, the purified water – 3 mg.

Indications to use

Avekort appoint at an inflammation and an itch of skin at a dermatosis (including psoriasis, atopic dermatitis) at which therapy is shown by glucocorticosteroids.

Contraindications

• Pink eels;
• Tuberculosis;
• Perioral dermatitis;
• Fungal, bacterial or virus (Herpes simplex, Herpes zoster) skin infection;
• Postvaccinal reactions;
• Syphilis;
• Pregnancy and the period of a lactation (long therapy, use on extensive sites of skin);
• Age up to 2 years;
• Hypersensitivity to drug components, and also to other glucocorticosteroids.

Relative contraindications (Avekort it is necessary to apply with care) are: use of occlusive bandages, drawing on the intertriginozny surface of skin and face skin, and also use of drug on extensive sites of skin and/or long therapy (in particular at children).

Route of administration and dosage

Avekort apply outwardly, applying with a thin layer on affected areas of skin.

Frequency rate of use – once a day.

Duration of a course depends on efficiency of therapy, and also portability of drug, existence and expressiveness of side effects. Duration of treatment averages 7-28 days.

Side effects

Probable side effects:

• Local reactions: an itch, burning, perioral dermatitis, paresthesias, acne rash, a folliculitis, maceration and an atrophy of skin, a hypertrichosis, hypopigmentation, allergic contact dermatitis, striya, accession of consecutive infection, a heat rash (the probability of their development increases at use of occlusive bandages);
• Systemic actions: long use of Avekort or putting ointment on extensive sites of skin (with a total area more than the area of palm the patient) or when using occlusive bandages, in particular at patients at children's and teenage age, can lead to development of side effects, characteristic of glucocorticosteroids, including an Icenco-Cushing syndrome and adrenal insufficiency.

Special instructions

If after Avekort's use for 14 days there is no effect, it is necessary to consult with the specialist and to specify the diagnosis.

Because of probability of development of systemic action of glucocorticosteroids at long therapeutic rates or putting drug on extensive sites of skin it is necessary to control function гипоталамо - pituitary and adrenal system.

The propylene glycol which is a part of drug can lead to emergence of irritation in a site of application. In this case it is necessary to stop Avekort's use and to appoint the corresponding therapy.

It is necessary to consider that glucocorticosteroids can change display of some skin diseases that can lead to difficulty of statement of the right diagnosis. Besides, Avekort can become the reason of a delay of healing of wounds.

At a long therapeutic course sudden phase-out of drug can lead to development of a syndrome of a ricochet which is shown as dermatitis with intensive erubescence and a burning sensation. In this regard drug withdrawal after a long course of treatment needs to be made gradually (it is recommended to pass to the intermittent scheme of treatment before completely to stop it).

Children are subject to bigger risk of development of an Icenco-Cushing syndrome and suppression of function гипоталамо - pituitary and adrenal system therefore at prolonged treatment disturbance of their growth and development is possible. Avekort's use for children a course longer was not studied than 3 weeks. Patients of children's age have to receive drug in the minimum doses sufficient for achievement of effect.

Medicinal interaction

Data on Avekort's interaction with other drugs / substances are not submitted.

Furoate of a mometazon on chemical properties is incompatible with alkalis.

Terms and storage conditions

To store in the place, dry, unavailable to children, at a temperature of 2-30 °C.

Period of validity – 3 years.