Peyroni's disease represents fibroplastic disturbance of position of a penis with the subsequent its curvature, and also existence of progressive fibrous changes. The disease carries the name of the famous surgeon F. Zhigo de Peyroni who opened it and began researches on treatment in 1743.
Heredity and genetic changes is the main reason for a disease of Peyroni, but injuries can become a push to a course of a disease. Scientific research showed that a number of general diseases and pathological changes influences Peyroni course of a disease.
The first symptoms of a disease can be poorly expressed and not cause fears, but within several weeks or months they amplify. Symptoms of a disease of Peyroni are disturbances of an erection and pain at it, and also the generative organ gets the bent form and becomes shorter, cicatricial fabric expands, plaques are formed, and the penis from two parties is deformed. As a result at patients erectile dysfunction and vasospasms of a generative organ is observed.
Penis injuries, including micro anguishes of fabrics, damages of small vessels and a hematoma can be a serious etiology of Peyroni. Often at heavy exercise stresses and intensive sexual intercourse plaques of fibrous type which provoke Peyroni's disease are formed.
This disease can be caused by an autoimmune disorder and emergence of pathological reactions, and also genetic predisposition to deviations in production of collagen.
In some cases Peyroni's disease was caused by side effects of medicines for treatment of a hypertension and heart diseases, and also beta-blockers. Before drug withdrawal it is necessary to undergo full diagnostic inspection for identification of relationships of cause and effect with Peyroni's disease.
Often this male disease is caused by disturbances of connecting fabric of a generative organ or age degenerative changes after 50 years.
Treatment of a disease of Peyroni needs to be begun with observation and the general inspection as recovery in certain cases can occur without medicamentous intervention. At Peyroni's disease operation is an extreme way of treatment.
The patient can be under observation of the attending physician and undergo regular consultations within 12 months. The medical specialist has to control constantly process of formation of plaques and not pass a serious curvature of a generative organ.
The doctor appoints a type of treatment taking into account avoiding of development of erectile dysfunction. Drug treatment of a disease of Peyroni is carried out by means of intravenous administration of aminopotassium benzoate, colchicine and vitamin E. Colchicine interferes with formation of excessive amount of collagen, and vitamin E is an additional tool in therapy.
In need of affected areas of a generative organ enter injections of the immunostimulating drugs, such as interferon, a collagenase, etc. The course of treatment makes several months of an intensive care. In the absence of medical effect appoint additional researches.
Nesbit's Peyroni's disease operation allows to eliminate completely bent site of a penis, but at the same time it becomes shorter. Such operation is appointed in the absence of results of other methods of treatment and only for patients with a curvature corner by no more than 45 degrees.
At Peyroni's disease operation on prosthetics is performed for elimination of a curvature and recovery of sexual function.
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