Application instruction:
Tsiklovir – antiviral synthetic medicine.
Active component of Tsiklovir – an acyclovir, has antiviral effect.
Effect of drug is based on formation of "defective" virus DNA which leads to suppression of reproduction of new generations of viruses.
Tsiklovir shows activity concerning a cytomegalovirus, and also viruses:
• Varicella zoster;
• Herpes simplex (types 1 and 2);
• Epstein-Burra.
Tsiklovir release in the form of the tablets containing active component an acyclovir in number of 200 mg and also in the form of cream and ointment for external use and an oculentum.
Active agent an acyclovir also is a part of some other medicines, such as Vivoraks, Provirsan, Medical OVIR, Gerperaks, Atsigerpin and the Acyclovir.
According to the instruction Tsiklovir appoint for system use in the following cases:
• At treatment of the infections caused by the Varicella zoster and Herpes simplex viruses of types 1 and 2 and also as a part of preventive actions, including states against the background of reduced immunity;
• In complex treatment after transplantation of marrow at the expressed immunodeficiency;
• For prevention of a Cytomegaloviral infection after operations on transplantation of marrow.
The oculentum Tsiklovir is locally applied in ophthalmology at treatment of a keratitis, and also other damages of eyes which are caused by the Herpes simplex virus.
Outside ointment and cream Tsiklovir according to the instruction use at infections of integuments which are caused by the Herpes simplex and Varicella zoster viruses.
Tsiklovir according to the instruction it is contraindicated to apply at hypersensitivity to active component (acyclovir) or the excipients which are a part of medicine.
The possibility of use of Tsiklovir at pregnancy is established individually by the doctor proceeding from estimated advantage or harm of drug for mother and the child.
Tsiklovir's use during feeding by a breast is not recommended to avoid release of active component of medicine with breast milk.
Tsiklovir in the form of ointment or external use cream do not use for drawing on mucous membranes of eyes, an oral cavity and a vagina.
Tsiklovir adults and children of two years in a one-time dosage inside accept 1-2 tablets with frequency rate of use from three to five times a day.
To children of younger age Tsiklovir's dosage is reduced, as a rule, twice.
Treatment duration medicine – from five to ten days, however against the background of a renal failure the mode of dosing it is necessary to correct.
Most often Tsiklovir according to reviews at intake causes:
• Vomiting;
• Nausea;
• Abdominal pain;
• Diarrhea;
• Headache;
• Skin rash;
• Increased fatigue;
• Dizziness;
• Hallucinations;
• Decrease in concentration of attention;
• Fever;
• Drowsiness or sleeplessness.
Much less often at Tsiklovir's reception according to reviews can develop:
• Passing increase in concentration in bilirubin blood;
• Hair loss;
• Erythropenia;
• Lymphocytopenia;
• Leukopenia.
At topical and external use Tsiklovir according to reviews can cause:
• The burning sensation arising in the place of application;
• Conjunctivitis;
• Blepharitis;
• Superficial dot keratitis;
• Itch;
• Skin rash;
• Erythema;
• Peeling;
• Xeroderma.
At Tsiklovir's hit on mucous membranes can begin an inflammation.
The risk of development of nephrotoxic action sharply increases at simultaneous use of Tsiklovir with nephrotoxic drugs, especially against the background of renal failures.
Strengthening of effect of Tsiklovir is noted at co-administration with immunostimulators.
Tsiklovir in the form of tablets it is possible to store no more than three years, in the form of outside ointment and cream – up to two years (on condition of observance of the recommended storage mode).
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