Felodip
Application instruction:
Felodip is the blocker of calcium channels having hypotensive and anti-anginal effect. Drug normalizes 
arterial pressure and improves blood circulation.
Felodip has positive reviews as effective medicine for treatment of cardiovascular diseases.
Structure and form of release
The main active ingredient – фелодипин 2,5-10 mg.
Auxiliary components: monohydrate of lactose, povidone, gipromelloza, magnesium stearate, anhydrous silicon, propyl gallate.
Felodip is issued in tablets on 2, 5 and 10 mg, film coated. Oxide of yellow iron, titanium dioxide, talc, oxide of red iron, propylene glycol is a part of a cover of each tablet.
Pharmacological action of Felodip
Felodip does not possess inotropic action, reduces probability of a myocardial infarction, normalizes a blood stream and has anti-ischemic effect. The lowering of arterial pressure occurs due to reduction of vascular resistance. Felodip has diuretic and spasolytic effect.
Drug reaches the maximum concentration in a blood plasma within 20-24 hours. It is gradually and evenly distributed in an organism, soaked up in digestive tract. The medical effect is shown within 3-6 hours after reception and lasts within a day.
Felodip forms inactive metabolites in a liver within 25-30 hours. Absorbability of drug does not depend on age of the patient, and also on functioning of a liver and kidneys. Felodip is brought from an organism with urine and a stake.
Felodip received good comments as the effective drug increasing elasticity of vessels, normalizing blood circulation in coronary arteries and reducing risk of emergence of morbid conditions. Drug does not cause orthostatic hypotonia and strengthens renal blood circulation.
Felodip's analogs
Felodipin, Plendil and Felogeksal are Felodip's analogs. Drugs have similar pharmacological effect and are applied to treatment of arterial hypertension and disturbances of blood circulation.
Indications to use
Felodip is shown to use at an arterial hypertension, stenocardia, arrhythmia, coronary heart disease, blood circulation disturbances, Reynaud's syndrome.
Application instruction of Felodip
According to the instruction 
Felodip it is necessary to accept inside 5 mg of 1 times a day, washing down with a plentiful amount of water. The maintenance dose of drug makes 10 mg a day. According to the recommendation of the attending physician for elderly patients the dosage can be lowered to 2,5 mg a day.
At stenocardia it is necessary to accept 5-10 mg of 1 times a day. The maximum daily dosage of drug should not exceed 20 mg.
During treatment it is necessary to control constantly the arterial pressure and concentration of glucose in blood. Felodip and Flekainid's concomitant use increases risk of development of side reactions.
According to the instruction Felodip it is impossible to appoint aged up to 18 years. Drug can reduce psychomotor reactions therefore the patients managing vehicles should limit the activity.
Contraindications
Felodip is contraindicated at hypersensitivity and individual intolerance of components of drug, hypotonia, bradycardia, an aortal stenosis, pregnancy and a lactation, aged up to 18 years.
With care drug is appointed to patients with a liver and renal failure, a mitral stenosis and an acute myocardial infarction.
Side effects of Felodip
Felodip can cause the following side reactions:
- from cardiovascular system – a sharp lowering of arterial pressure, stenocardia, a vazodilatation, arrhythmia;
- from the central nervous system – a headache, dizziness, a loss of consciousness, drowsiness, uneasiness, a tremor, an ataxy, a depression, an adynamy, lacks of coordination;
- from system of digestion – vomiting, nausea, diarrhea, dyspepsia, a lock, a meteorism, hepatitis, disturbances of appetite, disturbance of functioning of a liver;
- from circulatory system – anemia, a leukopenia, thrombocytopenia;
- allergic reactions – urticaria, dermatitis, skin rash, eczema, the raised photosensitivity, a Quincke's disease.
Name of drug
Price
Drugstore
Felodip тбл п / about pro-longum. 2.5mg No. 30, IVAX Corporation
449 rub.
Network of the Moscow drugstores of IFCFelodip тбл п / about pro-longum. 5 mg No. 30, IVAX Corporation
515 rub.
Network of the Moscow drugstores of IFCFelodip тбл п / about pro-longum. 10 mg No. 30, IVAX Corporation
865 rub.
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