Drug – the representative of antagonists of calcium ions. Use of Phenihydinum has hypotensive and anti-anginal effect. Blocks calcium channels, prevents receipt of calcium ions in cells of cardiomyocytes and smooth muscles of arterial channels.

According to the instruction Phenihydinum expands peripheral and coronary vessels, reduces the need of a myocardium for oxygen, makes negative inotropic impact, reduces the arterial pressure, OPSS and an afterload upon heart.

At chronic heart failure Phenihydinum, according to reviews, improves function of heart and leads to reduction of its sizes, oppresses aggregation of thrombocytes. At atherosclerosis improves post-stenotic circulation, has anti-atherogenous properties.

Indications to use of Phenihydinum

According to the instruction Phenihydinum is shown in the following cases:

Raynaud's disease;
arterial hypertension;
pulmonary hypertensia;
prevention of hypertensive crises;
bronkhoobstruktivny syndrome;
hypertrophic cardiomyopathy (including obstructive);
prevention of attacks of stenocardia (including Printsmetal's stenocardias).

Contraindications

In the instruction to Phenihydinum the following contraindications are specified:

heavy aortal stenosis;
pregnancy and breastfeeding;
hypersensitivity to nifedipine;
acute period of a myocardial infarction (first eight days);
the expressed arterial hypotension;
cardiogenic shock;
tachycardia;
heart failure in a decompensation stage.

Route of administration of Phenihydinum and mode of dosing

Phenihydinum according to the instruction is accepted inside in time or after food.

The dosing mode individual, depending on portability and indications to drug.

The initial dosage, as a rule, makes on one tablet twice a day. If necessary the dosage is increased to two tablets at one time. The maximum daily dosage makes 12 tablets. Duration of treatment averages one-two months.

At attacks Таблетки Фенигидин of stenocardia and for stopping of hypertensive crisis drug is used sublingual. For acceleration of effect one tablet of Phenihydinum is chewed and kept under language before its dissolution. At the same time the patient needs to be within an hour in a prone position. If necessary, in half an hour administration of drug can be repeated. After stopping of an attack it is possible to pass to oral administration.

Cancellation of medicine is carried out gradually.

Phenihydinum by-effects

According to reviews Phenihydinum is well transferred by patients. Quite often face reddening and an upper part of a trunk, and also the headache caused preferential by decrease in a tone of cerebral vessels of a brain and their stretching as a result of increase in inflow of blood on an arteriovenous anastomosis can be observed. In this case it is necessary to lower a dosage of drug or to accept it after meal.

Also the reviews of Phenihydinum testimonial of such by-effects as drowsiness, dizziness, nausea, hypotension, hypostasis of the lower extremities, heartbeat arrived.

Patients with stable stenocardia at the initial stages of treatment can have severe anginal pains, and at unstable stenocardia and a cardiosclerosis Phenihydinum can lead to aggravation of ischemia of a myocardium.