Giporamin

Giporamin – drug of a plant origin with antiviral action, active concerning herpes simplex viruses, Varitsella-Zoster, paramyxoviruses, adenoviruses, a cytomegalovirus, a respiratory and syncytial virus, influenza viruses of A and B, the human immunodeficiency virus (HIV).

Form of release and structure

• Ointment for external and topical administration: a homogeneous consistence, from color, grayish-white to light yellow with a brownish or grayish shade, with a specific smell (on 5, 10 or 20 g in aluminum tubas, 1 tuba in a pack cardboard);
• Sublingual tablets: a biconvex form, from light gray (the pinkish shade is possible) till light brown color with lighter and more dark asperges, with risky (on 10 pieces in blister strip packagings, 1, 2, 3 or 5 packagings in a pack cardboard; on 20 or 30 pieces in blister strip packagings, 1 packaging in a pack cardboard; on 25 pieces in banks from dark glass, 1 bank in a pack cardboard).

As active ingredient the dry purified extract from leaves of a krushinovidny sea-buckthorn is used:

• 1 g of ointment – 5 mg (the maintenance of the sum of tannins in terms of beef-woods – 60%);
• 1 tablet – 20 mg.

Ointment excipients: the twin-80 (polysorbate-80), ethanol of 95%, vaseline medical, methylparahydroxybenzoate, поливинокс (vinylene), emulsifier No. 1, water cleared, oil eucalyptus.

Additional components of tablets: calcium stearate, sodium carboxymethylcellulose, cocoa powder, refined sugar, vanillin.

Indications to use

In the form of ointment Giporamin appoint for treatment and prevention:

• Acute and recurrent forms of a herpes simplex of genital and extragenital localization;
• Chicken pox;
• The surrounding herpes;
• Cytomegaloviral infection.

In the form of tablets Giporamin is applied to treatment and prevention:

• Flu A and B;
• Parainfluenza;
• Adenoviral, respiratory and syncytial and other acute respiratory viral infections (ARVI);
• The quinsy which is developing owing to a SARS and followed by rhinitis;
• Acute and recurrent forms of a herpes simplex of genital and extragenital localization;
• Cytomegaloviral infection;
• Chicken pox;
• The surrounding herpes.

Contraindications

The main contraindication to Giporamin's use is individual sensitivity to his components.

In the form of tablets drug is not appointed to children up to 3 years, in the form of ointment – up to 2 months.

There are no data on safety and efficiency of use of Giporamin in tablets at pregnancy and feeding by a breast. In the form of ointment during these periods drug can be used on doctor's orders.

Route of administration and dosage

Ointment for topical and external use

It is recommended to begin treatment as soon as possible, after emergence of the first symptoms of a disease.

In the form of ointment drug inflict on the centers defeats of mucous membranes and skin of 4-6 times a day.

Duration of treatment of envy for weight of a course of a disease: easy forms – from 3 to 10 days, severe and recurrent forms – not less than 2-3 weeks. If necessary conduct repeated courses.

Sublingual tablets

It is recommended to begin administration of drug as soon as possible, after emergence of the first symptoms of a disease.

Tablets apply sublingual – hold under language before full dissolution.

Flu, adenoviral, respiratory and syncytial and other viral infections of upper parts of respiratory tracts:

• Adults – on 1 tablet of 4-6 times a day;
• Teenagers are more senior than 12 years – on 1 tablet 3-4 times a day;
• Children of 3-12 years – on ½-1 to a tablet 2-4 times a day.

Treatment duration: flu – is not less than 3 days, in other cases – not less than 5 days.

Shingles, chicken pox, Cytomegaloviral infection, herpes infection, and also other virus damages of mucous membranes and integuments:

• Adults and teenagers are more senior than 12 years – on 1 tablet of 4-6 times a day;
• Children of 6-12 years – on 1 tablet 3-4 times a day;
• Children of 3-6 years – on ½ tablet 2-4 times a day.

Duration of therapy is defined individually depending on weight of a course of a disease: an easy current – from 3 to 10 days, a heavy and recurrent current – 2-3 weeks. If necessary conduct repeated courses.

For prevention of Cytomegaloviral and herpes infections when performing immunosuppressive therapy at postoperative patients, Giporamin appoint on 1 tablet 3 times a day within 5-7 days.

Side effects

• Ointment: allergic reactions;
• Tablets: at prolonged use – increase in coagulability of blood.

Special instructions

At Giporamin's appointment in the tableted form a sick diabetes mellitus it is necessary to consider that 1 tablet contains 529,9 mg of sucrose.

The most expressed medical effect is reached at a combination of dosage forms of Giporamin (ointment and sublingual tablets).

Phytodrug does not render a negative impact on ability to manage vehicles and to work with difficult mechanisms.

Medicinal interaction

In need of Giporamin it is possible to combine with other medicines (antimicrobic, synthetic antiviral drugs, means for symptomatic therapy).

Terms and storage conditions

To store in the dry, dark place unavailable to children, at a temperature: tablets – 15-25 ºС, ointment – 10-15 ºС.

Period of validity – 2 years.