Erespal

Erespal – the medicine entering into the H1 antihistamines group.

Pharmacological action of Erespal

Erespal is the means possessing spasmolytic, antihistaminic and antiinflammatory effects.

Antiinflammatory effect of drug is caused by activity of the fenspirid which is contained in its structure which promotes reduction of products of some biologically active agents (first of all, cytokines, free radicals and some other) playing a role in development of a bronchospasm and inflammation. Also фенспирид blocks alpha adrenoceptors at which stimulation there is an increase in secretion of bronchial glands. In general, the effect of a fenspirid which had on an organism can be described as follows: interferes with development of an inflammation and obstruction of bronchial tubes, promotes spasmolytic activity.

Release form

According to the instruction to Erespal, there are two forms of release of medicine now:

• round tablets of white color. Tablets have the biconvex form, are covered with a cover. Content of active agent (a hydrochloride of a fenspirid) makes 80 mg. One packaging contains 30 pieces;
• the transparent syrup possessing in orange color. Formation of a deposit which after agitation vanishes is admissible. The volume of syrup makes 150 ml. It is packed into dark bottles from plastic.

Indications to Erespal's use

Numerous reviews of Erespala noted efficiency of drug at fight against various diseases of the lower and upper parts of respiratory tracts. First of all, Erespal is effective at the following diseases:

• at a nasopharyngitis and laryngitis;
• at otitis and sinusitis of various genesis (including seasonal allergic and allergic, having constant character);
• at a rinotrakheobronkhita;
• at bronchitis;
• at the isolated or complicated bronchial asthma as a maintenance therapy;
• at the respiratory phenomena accompanying measles, flu, whooping cough.

Contraindications

The instruction to Erespal warns about existence of contraindications to drug. Among them:

• age less than 14 years (in this case syrup is recommended);
• hypersensitivity to Erespal's components. It is necessary to consider that the allergy is caused most often фенспирид, yellow dye sanst CFC, spent on drink - and methylparabens.

Application instruction of Erespal

Erespal it is necessary to accept to food, carefully shaking up. The dosage of drug depends on age of the patient.

So, the adult appoint 1 tablet of Erespal (that corresponds to 80 mg of a fenspirid) from 2 to 3 times a day. Erespal in the form of syrup accept in number from 3 to 6 tablespoons a day, the content of syrup makes at the same time from 45 to 90 ml. It is also necessary to mean that one tablespoon of syrup contains 9 g of sucrose and to 30 mg of a fenspirid.

Erespal in the form of tablets is not recommended to children, drug should be accepted in a syrupy form.

For teenagers and children whose age less than 14 years, the dosage is calculated according to the following scheme: 4 mg of medicine on 1 kg of body weight a day.

To kids from the birth up to 2 years (if their weight does not exceed 10 kg) appoint from 2 to 4 teaspoons of syrup (about 10-20 ml) a day. Drug can be added to a small bottle with nutritious mix. It is important to consider that one teaspoon contains 3 g of sucrose and 10 mg of active agent – a fenspirid.

As a rule, the course of treatment according to the instruction to Erespal does not exceed 20-30 days. In need of repetition of a course of treatment it is necessary to get advice of the attending physician.

Side effects of Erespal

Erespal's use is capable to entail emergence of side reactions. It is recommended to see a doctor at the following types of indispositions:

• when developing moderate tachycardia (decrease in a dosage of drug most often is a solution);
• at nausea, pain in epigastriums, gastrointestinal frustration, vomiting and diarrheas;
• at drowsiness, dizziness;
• at the increased fatigue and an adynamy;
• at an allergy in the form of an erythema, rash, small tortoiseshells, a skin itch and a Quincke's disease.

Special instructions

At purpose of syrup Erespal patients with a diabetes mellitus should mean that drug contains sucrose in the ratio: 1 its tsp contains 3 g, in 1 tablespoon – 9 g.

According to medical reviews of Erespala, administration of drug during pregnancy and during feeding by a breast is not recommended since now there are no sufficient clinical data about influence of medicine on the child.

Erespal and analogs of drug are capable to cause drowsiness owing to what are not recommended for use during implementation of the activity demanding the increased concentration.

Analogs

Medicine, therapeutic effect of which reception it is equal to effect of Erespal's reception – Fenspirid.

Storage conditions

Syrup Erespal is stored not longer than 3 years, a tablet – no more than 2 years. Both forms of drug are recommended to be stored at a temperature which is not exceeding a mark of 25 °C far from children.