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Clemastinum

Clemastinum – medicine of the expressed antipruritic and antiallergic action, a blocker histamine H1 receptors.

Form of release and structure

Dosage form of Clemastinum – a tablet: flat, round, 7 mm in the diameter, almost white or white color, on one of the parties – a notch (on 10 pieces in blisters, 2 blisters in a cardboard pack).

Structure of 1 tablet:

  • Active ingredient: Clemastinum (in the form of a fumarat) – 1 mg;
  • Auxiliary components: monohydrate of lactose, talc, corn starch, magnesium stearate.

Indications to use

  • Pruritic dermatosis;
  • Skin itch;
  • Contact dermatitis;
  • Small tortoiseshell;
  • Acute and chronic eczema;
  • The reactions connected with stings of insects;
  • Rhinopathies of allergic genesis;
  • Hay fever.

Contraindications

Absolute:

  • Diseases of lower parts of respiratory tracts (including bronchial asthma);
  • Lactation period;
  • Children's age till 1 year;
  • Use along with monoamine oxidase inhibitors (MAO);
  • Hypersensitivity to Clemastinum components, and also to other blockers histamine H1 receptors.

Relative (drug is taken with caution in connection with the increased probability of side effects):

  • Closed-angle glaucoma;
  • The stenosing stomach ulcer;
  • The obstructive phenomena in peloric and duodenal areas;
  • The prostatauxe which is followed by disturbances of an urination;
  • The obstructive phenomena in a bladder neck;
  • Children's age up to 6 years.

At pregnancy it is possible to use Clemastinum only according to vital indications.

Route of administration and dosage

Pill is taken inside.

The recommended dosing mode depending on age:

  • Adults and children are more senior than 12 years: on 1 mg 2 times a day, in the morning and in the evening; in case of need about 6 mg are allowed to increase a daily dose;
  • Children aged from 6 up to 12 years: on 0,5-1 mg 2 times a day.

Side effects

  • Central Nervous System (CNS): drowsiness, feeling of fatigue; seldom – a tremor, dizziness; in isolated cases (it is preferential at children) – a promoting effect on TsNS;
  • Alimentary system: the dispeptic phenomena, including nausea, pains in epigastriums, vomiting, a lock, dryness in a mouth; in isolated cases – diarrhea, anorexia;
  • Cardiovascular system (CCC): seldom – a lowering of arterial pressure (it is preferential at elderly patients), premature ventricular contraction, heartbeat;
  • Urinary system: seldom – a dysuria;
  • Respiratory system: seldom – a condensation of a bronchial secret with difficulty of department of a phlegm;
  • Dermatological reactions: seldom – a photosensitization;
  • Allergic answers: seldom – urticaria, skin rash;
  • Others: seldom – feeling of squeezing in a thorax.

Special instructions

It is not necessary to apply Clemastinum at the same time with somnolent medicines and/or alcohol.

Drug exerts impact on concentration of attention and speed of psychomotor reactions therefore during therapy it is not recommended to work with difficult mechanisms and to manage motor transport.

Medicinal interaction

Clemastinum in case of simultaneous use has exponential effect on medicines, the oppressing TsNS (sedative, somnolent, tranquilizers), and also on ethanol and etanolsoderzhashchy drugs.

Terms and storage conditions

To store in the place unavailable to children, at a temperature of 15-25 °C.

Period of validity – 4 years.

 
 
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