Naksodzhin
Application instruction:
Naksodzhin – antiprotozoan drug.
Form of release and structure
Dosage form of Naksodzhin – a tablet: convex, round, white or slightly yellowish color, on one party the line of a break (on 6 pieces in bottles of dark glass, 1 bottle in a cardboard pack).
Structure of 1 tablet:
- Active ingredient: ниморазол – 0,5 g;
- Auxiliary components: starch corn, cellulose microcrystallic, methyl cellulose 400, stearic acid.
Indications to use
Drug is intended for therapy of a number of the infections caused by the following microorganisms sensitive to a nimorazol:
- Trichomonas vaginalis – urogenital trichomoniasis;
- Giardia lamblia – a lambliasis;
- Entamoeba histolytica – an amebiasis;
- Gardnerella vaginalis – vaginita;
- Candida albicans, Actinomyces israelii, Treponema pallidum – Vincent's ulitis, or an acute ulcer and necrotic ulitis.
Contraindications
- Acute neurologic pathologies;
- Diseases of the central nervous system (CNS);
- Renal and/or liver failure;
- Pregnancy;
- Lactation period;
- Children's age;
- Hypersensitivity to Naksodzhin's components and derivatives of a nitroimidazole.
Route of administration and dosage
Tablets are intended for intake.
The recommended dosing mode – 0,5 g (1 tablet) 2 times a day for 6 days or 2 g (4 tablets) of 1 times a day for 1-2 days.
Side effects
- Alimentary system: heartburn, nausea, vomiting, abnormal liver function, gastralgia;
- Central and peripheral nervous system: drowsiness, dizziness, polyneuropathy, exacerbation of mental diseases, paresthesias;
- Allergic reactions: enanthesis.
Symptoms of overdose are: dizziness, gastrointestinal discomfort (nausea, vomiting, heartburn, diarrhea), neurologic symptoms (pricking, paresthesias, catalepsy and convulsions). For improvement it is necessary to make fortunes a gastric lavage and further to carry out a symptomatic treatment.
Special instructions
In order to avoid repeated infection at therapy of trichomoniasis it is necessary to carry out treatment of both sexual partners at the same time, even in case disease symptoms at one of them are absent.
Under strict medical control it is required to carry out treatment of patients with an exacerbation of neurologic diseases.
Upon termination of a course several days can remain clinical symptoms of an inflammation at full bacteriological treatment.
Medicinal interaction
Simultaneous use of Naksodzhin with alcohol can cause disulfiramopodobny reactions.
Nimorazol can strengthen anticoagulating effect of warfarin and reduce clearance of lithium and Phenytoinum.
Cimetidinum can increase, and phenobarbital – to reduce Naksodzhin's concentration in plasma.
Terms and storage conditions
To store at a temperature up to 25 °C. To protect from children.
Period of validity – 5 years.
Name of drug
Price
Drugstore
Naksodzhin тбл 500 mg No. 6, Pharmacia & Upjohn/Pfizer
336 rub.
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