Нормакс

Нормакс – antibacterial agent from group of ftorkhinolon.

Form of release and structure

• Tablets, film coated: a kapsulovidny form, almost white or white color, on one of the parties – risk (on 6 or 10 pieces in strips from aluminum foil, 1 strip in a pack cardboard);
• Drops eye and ear 0,3%: transparent, colourless or weak-yellow solution, free from any particles (on 5 ml in dark glass bottles or polyethylene bottles droppers, in a pack a cardboard 1 glass bottle complete with a cap dropper or 1 bottle dropper).

Active agent – norfloxacin, its contents:

• 1 tablet – 400 mg;
• 1 ml of drops – 3 mg.

Additional components of tablets: sodium lauryl sulfate, starch sodium the glycollate, talc purified, a gidroksipropilmetiltsellyuloza, silicon dioxide colloid, titanium dioxide, magnesium stearate, microcrystallic cellulose.

Excipients of drops: water for injections, sodium chloride, dinatrium эдетат, ice acetic acid, a benzalkoniya chloride.

Indications to use

In the form of tablets of Normaks appoint for treatment of the following infectious and inflammatory diseases caused by microorganisms, sensitive to norfloxacin:

• Ophthalmologic infections;
• Infections of skin and soft tissues;
• Intestinal infections;
• Infections of a middle ear, throat, throat, adnexal bosoms of a nose;
• Infections of bodies of a small pelvis (including adnexitis and prostatitis);
• Diseases of urinary tract.

In the form of drops of eye and ear Normaks it is applied to treatment of the following diseases of infectious and inflammatory character caused by microorganisms, sensitive to norfloxacin:

• Keratitis;
• Blepharites;
• Conjunctivitis (including gonococcal);
• Blefarokonjyunktivita;
• Keratoconjunctivites;
• Internal otitis;
• Acute and chronic average otitis;
• Outside otitis;
• Infectious eustachitis;
• Trachoma;
• Corneal ulcer.

Besides, in drops drug is used for prevention:

• Infections after removal of a foreign body from a conjunctiva or a cornea, before an operative measure, after damage by physical or chemical means;
• Infectious otitises after extraction of a foreign body from outside acoustical pass (in case of damage of tissues of ear), at injuries, before and after surgical intervention.

Contraindications

For both dosage forms:

• Period of pregnancy and lactation;
• Hypersensitivity to any component of drug or another medicinal means from group of ftorkhinolon.

In pediatrics of a tablet of Normaks do not appoint to children up to 15 years, a drop eye and ear – up to 18 years.

In the form of tablets drug should be used with care to patients with the expressed renal failures and/or a liver, epilepsy or a convulsive syndrome of other etiology.

Route of administration and dosage

Tablets, film coated
The tableted form of drug should be taken inside.

Usually appoint on 1 tablet 2 times a day. At the heavy course of an infectious disease the single dose can be increased to 2 tablets.

Therapy duration in each case is defined individually, but makes not less than 3 days.

Drops eye and ear
In the form of drops of Normaks it is intended for topical administration.

The recommended doses:

• Infectious diseases of eyes in an acute phase: in an initiation of treatment – on 1-2 drops each 15-20 minutes with gradual decrease in frequency rate of instillations;
• Infectious diseases of eyes with moderately expressed current: on 1-2 drops of 2-6 times a day;
• Acute and chronic trachoma: on 2 drops in each eye 2-4 times a day within 1 month and more;
• Ear diseases: on 5 drops 3 times a day.

At ear diseases before instillation of a drop it is necessary to warm up to body temperature. It is necessary to dig in drug in previously cleared outside acoustical passes. For convenience of holding a procedure it is recommended to lay down on one side or to throw back the head to facilitate process of an instillation. After instillation within 2 minutes the head needs to be held in the same situation. In need of an ear it is possible to enclose a wadded turunda. It is necessary to continue treatment within 48 hours after disappearance of symptoms of a disease.

Side effects

• Allergic reactions: rash, itch, Quincke's edema;
• Alimentary system: abdominal pain, heartburn, nausea, diarrhea, anorexia;
• Central nervous system: the increased fatigue, a headache, frustration of a dream, feeling of alarm, irritability, вертиго;
• Urinary system: intersticial nephrite.

Special instructions

At co-administration of the antacids or drugs containing zinc, magnesium, сукральфат, calcium or iron between administrations of drugs it is necessary to observe at least 2-hour intervals.

In the form of drops of Normaks it is intended only for topical administration. For achievement of the maximum effect at the heavy course of infectious process drug is recommended to be combined with system antimicrobic therapy.

At an instillation it is necessary to protect a dropper and solution from pollution.

Within 30 minutes after instillation of drops in eyes it is necessary to refrain from driving of the car and performance of potentially dangerous types of the works demanding the clearness of visual perception and special attention.

Medicinal interaction

Possible medicinal interactions at simultaneous use of Normaks in the tableted form along with other medicines:

• The antacids and drugs containing zinc, magnesium, сукральфат, calcium or iron: norfloxacin absorption decreases;
• Cyclosporine: its concentration in blood increases;
• Warfarin: its anticoagulating effect increases.

Eye and ear drops of Normaks are incompatible with drugs which have physically or chemically unstable value рН 3-4.

Terms and storage conditions

To store at a temperature up to 25 ºС in the place, unavailable to children, protected from light.

Period of validity – 2 years. Drops after opening of a bottle can be used within 1 month.